DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zdhhc8 and zdhhc6

DIOPT Version :9

Sequence 1:	NP_001259382.1	Gene:	Zdhhc8 / 31887	FlyBaseID:	FBgn0085478	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001191086.1	Gene:	zdhhc6 / 324468	ZFINID:	ZDB-GENE-030131-3189	Length:	412	Species:	Danio rerio

Alignment Length:	207	Identity:	60/207 - (28%)
Similarity:	87/207 - (42%)	Gaps:	60/207 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 GVITFFVLANFTL--------ATFMDPGIIP---KASPDEDCEEELRAPLYKNAEINGITVKMKW 100
            |.|.|.:|.|:|:        |.|:.||.||   |....:|.       :|           :::
Zfish    54 GSINFIMLINWTVLILYNYFNAMFVGPGYIPLEWKPEKQQDI-------MY-----------LQF 100

  Fly   101 CVTCKFYRPPRCSHCSVCNHCIETFDHHCPWVNNCIGRRNYRFF--FFFLVSLS-IHMLSIFSLC 162
            |..|:.|:.||..||..||.|:...||||||:|||.|..|:.:|  |..|..|. ||...||.:.
Zfish   101 CRLCQGYKAPRSHHCRKCNRCVMKMDHHCPWINNCCGHLNHAYFTSFLLLAPLGCIHAALIFIMT 165

  Fly   163 LVYVL-----------------------KIMP-NIKDTAPIVAIILMGLVTILAIPIFGLTGF-H 202
            :...|                       .||| :|...|..:..:.:.|.|.:|:   |:..| .
Zfish   166 MYTQLYDRISFGWSSVKIDMSAARHIHHPIMPFSIAAFAATLFALGLALGTTIAV---GMLFFIQ 227

  Fly   203 MVLVSRGRTTNE 214
            |.::.|.||:.|
Zfish   228 MKVILRNRTSIE 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	zf-DHHC	94..219	CDD:279823	45/149 (30%)
zdhhc6	NP_001191086.1	DHHC	95..241	CDD:396215	46/166 (28%)
zdhhc6	NP_001191086.1	Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9H6R6	409..412
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900