Protein Alignment Zdhhc8 and ZDHHC1

DIOPT Version :10

• Sequence 1: NP_001259382.1
• Gene: Zdhhc8 / 31887
• FlyBaseID: FBgn0085478
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_037436.1
• Gene: ZDHHC1 / 29800
• HGNCID: 17916
• Length: 485
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 67/246 - (27%)
• Similarity: 100/246 - (40%)
• Gaps: 63/246 - (25%)

  Fly    16 AWIVLLLTTFLFF--FYPCQFYVKSHPWV---LAYQGVITFFVLANFTLATFMDPGIIPKASPDE 75
            ||::.|....:.|  ..|    :..|.||   .|..|.|....|.....|..:||.       |.
Human    55 AWLLYLFFAVIGFGILVP----LLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPA-------DA 108

  Fly    76 DCEEELRA---PLYKNAEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHCPWVNNCIG 137
            :..::..|   |::..:: :...::...|..|......|..|||.||.|:..|||||.|:|||:|
Human   109 NVRDKSYAGPLPIFNRSQ-HAHVIEDLHCNLCNVDVSARSKHCSACNKCVCGFDHHCKWLNNCVG 172

  Fly   138 RRNYRFFFFFLVSLSIHMLSIFSLCLV--YV----------------LKIMPNIKD-------TA 177
            .||||   .||.|::..:|.:..|.||  ||                .:::.|..|       .|
Human   173 ERNYR---LFLHSVASALLGVLLLVLVATYVFVEFFVNPMRLRTNRHFEVLKNHTDVWFVFLPAA 234

  Fly   178 PI-----------VAIILMGLVTILAIPIFG-LTGFHMVLVSRGRTTNEQV 216
            |:           ..:||:||   |:..:.| |..||:.|:....||.|.:
Human   235 PVETQAPAILALAALLILLGL---LSTALLGHLLCFHIYLMWHKLTTYEYI 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	DHHC	99..219	CDD:396215	49/155 (32%)
ZDHHC1	NP_037436.1	Mediates interaction with STING1. /evidence=ECO:0000269|PubMed:25299331	1..271		63/233 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41
		DHHC	129..284	CDD:396215	49/160 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	324..358
		DPBB_RlpA_EXP_N-like	<362..>400	CDD:455124
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	462..485