DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zdhhc8 and Zdhhc19

DIOPT Version :9

Sequence 1:	NP_001259382.1	Gene:	Zdhhc8 / 31887	FlyBaseID:	FBgn0085478	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001034348.1	Gene:	Zdhhc19 / 288045	RGDID:	1309014	Length:	359	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	86/252 - (34%)
Similarity:	127/252 - (50%)	Gaps:	30/252 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 YIPATFAWIVLLLTTF---LFFFYPCQFYVKSHPWVL-AYQG---VITFFVLANFTLATFMDPGI 67
            :.|:.||...:.|..|   |||.:||::.|::..||. |..|   ::|||.|.:.   .|.||||
  Rat    28 FFPSLFAAFNVSLLVFLSGLFFGFPCRWLVQNGEWVFPAVTGPLFILTFFSLVSL---NFSDPGI 89

  Fly    68 IPKASPDEDCEEELRAPLYKN-AEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHCPW 131
            :.:.|..||       |...: ..:|....:::||..|.|:||||..||..||.|:|.|||||.|
  Rat    90 LHRGSVSED-------PRTVHVVRVNQRAFRLEWCPKCLFHRPPRTYHCPWCNICVEDFDHHCKW 147

  Fly   132 VNNCIGRRNYRFFFFFLVSLSIHMLSIFSLCLVYVLKI--MPNIKDTAP--IVAIILMGLVTILA 192
            ||||||.||:|.|...::.|.::..::...||::::..  :|...|.|.  :||:...|.:
  Rat   148 VNNCIGHRNFRLFVLLILFLCLYSGALLVTCLMFLIHTSHLPFSLDKAMAILVAVPAAGFL---- 208

  Fly   193 IPIFGLTGFHMVLVSRGRTTNEQVTGKFKGGYNPFSRGC---WHNCCYTQFGPQYPS 246
            ||:|.|.....:.|||...:.|......: .||||.:|.   |:.......||.|.|
  Rat   209 IPLFLLMLIQALSVSRAERSYESKCRDHE-EYNPFDQGFAKNWYLTMCAPLGPNYMS 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	zf-DHHC	94..219	CDD:279823	47/128 (37%)
Zdhhc19	NP_001034348.1	zf-DHHC	112..230	CDD:279823	46/121 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264614at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.780