DRSC/TRiP Functional Genomics Resources

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Protein Alignment Zdhhc8 and ZDHHC22

DIOPT Version :9

Sequence 1:NP_001259382.1 Gene:Zdhhc8 / 31887 FlyBaseID:FBgn0085478 Length:1052 Species:Drosophila melanogaster
Sequence 2:NP_001351101.1 Gene:ZDHHC22 / 283576 HGNCID:20106 Length:263 Species:Homo sapiens


Alignment Length:237 Identity:57/237 - (24%)
Similarity:93/237 - (39%) Gaps:64/237 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 PATFAWIVLLLTTF---LFFFYPCQFYVKSHPWV------LAYQGVITFFVLANFTLATFMDPGI 67
            ||.|  :.:.|.||   ||.|.|.   ::..|..      ....|.:..|:.|| .|..::   :
Human    12 PAYF--LCISLVTFVLQLFLFLPS---MREDPAAARLFSPALLHGALFLFLSAN-ALGNYV---L 67

  Fly    68 IPKASPDE--DCEEELRAPLYKNAEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHCP 130
            :.:.|||:  .|:              |.:.:...|.:      |....|.||.......||||.
Human    68 VIQNSPDDLGACQ--------------GASARKTPCPS------PSTHFCRVCARVTLRHDHHCF 112

  Fly   131 WVNNCIGRRNYRFFFFFLVSLSIHMLSIFSLCLVYVLKIMPNIKDTAPIVAIILM---------G 186
            :..||||.||.|.|..|.:..|:..|......:.|:..:: :|....|:..:.|:         |
Human   113 FTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVAYISAVL-SISFAHPLAFLTLLPTSISQFFSG 176

  Fly   187 LV------TILAIPIF---GL--TGF---HMVLVSRGRTTNE 214
            .|      .||.:.::   ||  .||   .::|:.||:|.::
Human   177 AVLGSEMFVILMLYLWFAIGLACAGFCCHQLLLILRGQTRHQ 218

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zdhhc8NP_001259382.1 zf-DHHC 94..219 CDD:279823 36/144 (25%)
ZDHHC22NP_001351101.1 DHHC 92..218 CDD:366691 35/126 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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