DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zdhhc8 and zdhhc13

DIOPT Version :9

Sequence 1:	NP_001259382.1	Gene:	Zdhhc8 / 31887	FlyBaseID:	FBgn0085478	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	XP_002942880.3	Gene:	zdhhc13 / 100493145	XenbaseID:	XB-GENE-997024	Length:	612	Species:	Xenopus tropicalis

Alignment Length:	294	Identity:	83/294 - (28%)
Similarity:	120/294 - (40%)	Gaps:	73/294 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RYIPA-TFAWIV--LLLTTFLFFFYPCQFYVKSHPWV--LAYQ--GVITFFVLANFTLATF-MDP 65
            |.:|| .|:..:  :.||.|::|.          |.:  :|:|  .:|:..:|..|...|: .||
Frog   335 RSLPAIIFSCCIFWMFLTWFIYFL----------PGLARVAFQLPFIISMLLLFYFFYKTWCTDP 389

  Fly    66 GIIPKASPDEDCEEELRAPLYKNAEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHCP 130
            |.| |:|     |||.|..:...||...:..:: :|.:|...:|.|..||..||.|:..||.||.
Frog   390 GYI-KSS-----EEESRQTIITLAEAGCLDARL-FCTSCLVKKPLRSMHCHACNSCVARFDQHCV 447

  Fly   131 WVNNCIGRRNYRFFFFFLVSLSI---------------H------------MLSIFSLCLVYVLK 168
            |...|||..|..||..||.||::               |            .||....|..:||.
Frog   448 WTGQCIGAGNQHFFVLFLASLAVVGNWMIYATSVYWSDHCGMGSRKDGIWATLSQIVNCSPWVLY 512

  Fly   169 IMPNIKDTAPIVAIILMGLVTILAIPIFGLTGFHMV-LVSRGRTTNEQVTGKFKGGYNPFSRGCW 232
            |...:  :|..|...||.||.:..|...|||....: |..:.|....||:.:    ..||:|||.
Frog   513 IFCLV--SAFTVWATLMLLVQLFQISFLGLTTQERISLQVQNRHLKHQVSLR----RTPFNRGCL 571

  Fly   233 HN------C-CY-------TQFGPQYPSLLNPKK 252
            .|      | |:       ..:..||...:.|.:
Frog   572 QNLADFFHCQCFGLIKSQPIDWTKQYHGAIPPSR 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	zf-DHHC	94..219	CDD:279823	45/152 (30%)
zdhhc13	XP_002942880.3	Ank_2	46..136	CDD:372319
		ANK repeat	71..102	CDD:293786
		PHA03095	82..>246	CDD:222980
		ANK repeat	104..136	CDD:293786
		ANK repeat	138..169	CDD:293786
		ANK repeat	171..237	CDD:293786
		DHHC	327..>549	CDD:388695	68/232 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910