Protein Alignment CG31643 and FASTKD3

DIOPT Version :10

• Sequence 1: NP_723145.1
• Gene: CG31643 / 318867
• FlyBaseID: FBgn0051643
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_076996.2
• Gene: FASTKD3 / 79072
• HGNCID: 28758
• Length: 662
• Species: Homo sapiens
• Alignment Length: 691
• Identity: 143/691 - (20%)
• Similarity: 238/691 - (34%)
• Gaps: 224/691 - (32%)

  Fly   279 IHMLNIPVWSQ--------------------------THTQLIREVMLVLRPCIHQMESADLKSI 317
            :|.|..||:||                          |.::.:...:..:......|.:..|:.|
Human    73 LHPLGGPVFSQVSDCDRLEQNVKNEESQMFYRRLSNLTSSEEVLSFISTMETLPDTMAAGALQRI 137

  Fly   318 CRTFLHHQEPAALIEPLKKALEKLLQEEGTADALFCAVPFATPLQRDQYLHQFKELLYSEEAWQQ 382
            |             |..||..::.|.:|...:::|.|:.|           ||:     :|..|.
Human   138 C-------------EVEKKDGDQGLPKEILENSIFQALCF-----------QFE-----KEPSQL 173

  Fly   383 PNASGHLFSVLRALKVSDIEFCNTYWSGVVKELESCPEKHLHLRFLRHCQRYMNFNNNL--GGTY 445
            .|.|  |.:.|:||.:..::                |:..|.|..:..||      |.|  ||
Human   174 SNTS--LVTALQALILLHVD----------------PQSSLLLNLVAECQ------NRLRKGG-- 212

  Fly   446 RHLELERKLSRMCMNAIEHDIAGRLPAKFARLASFVLAYGQTPLAWKKFPNFLLSKMLAMAPQLG 510
                  .::..:|:                                                 ||
Human   213 ------MEVRNLCI-------------------------------------------------LG 222

  Fly   511 IQDCFLLSRGMQIASELRFRQHLPALAGMQLST--------MDSILIGCAER---HLRDAEKDPL 564
            .....|.|.|. :..||...|    |.|.:|.|        :..||..|.|:   |.....|  :
Human   223 ESLITLHSSGC-VTLELIINQ----LQGEKLETFTPEDIVALYRILQACTEKVDEHQTFLNK--I 280

  Fly   565 NASELSMIVRTLSHR---KKLKNTVVYNQA--------LAQYKNLH----CNDLNSRVVRDMAYN 614
            |...|| ||..||.:   :.|...||.:|:        |.:|...|    .|:...||:....|.
Human   281 NNFSLS-IVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEELRRVLEAFIYF 344

  Fly   615 FNASNFFV---------------PELLESMFAYISE------------------QHDHVSGDTVE 646
            .:...||.               ||::..:..|.|.                  |.:..|...:.
Human   345 GHHDTFFTKALEHRVAAVCLTLDPEVVCRVMEYCSRELILSKPILNAVAETFVCQTEKFSPRQIS 409

  Fly   647 KVLTCSYNLGYMPASVEALNHASE-VLLRDFDQMSGLSVVQACLALCFYKSIPEQLINQVFCVKF 710
            .::.....|.|:|.:..||....| ||...|:.....|:::...:....:..|...:.::|...|
Human   410 ALMEPFGKLNYLPPNASALFRKLENVLFTHFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKPLF 474

  Fly   711 IQRI---EDEIQVCYSKATYPERVLNLVMQLNRTVCLDF--PEANVPWFQ-QNYIEAQISKKSLI 769
            :||:   |..:.. .|:|...:..|..|::     |..:  |:. :|.:| ::::....|.::.:
Human   475 LQRLQGKESHLDT-LSRAQLTQLFLASVLE-----CPFYKGPKL-LPKYQVKSFLTPCCSLETPV 532

  Fly   770 PSESTTEVKQLLHQLLQNDKHFRCNHTTPYGYQIDFVIHFDRDKNPIPAPPVEATMLDRITKVAI 834
            .|:....||..|..||....:|.....|||.|.||..|..|.:...:|:...|    |...::|:
Human   533 DSQLYRYVKIGLTNLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFVLPSTANE----DIHKRIAL 593

  Fly   835 LLLKLDSFCENDLTALRGPESLKMRHLEMMGYKVMQINEHD 875
            .:.....||.|. ..|.|.|::|.|||:::||:|:||..|:
Human   594 CIDGPKRFCSNS-KHLLGKEAIKQRHLQLLGYQVVQIPYHE 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31643	NP_723145.1	FAST_1	645..715	CDD:461999	15/73 (21%)
		FAST_2	735..817	CDD:462448	21/84 (25%)
		RAP	834..894	CDD:214932	16/42 (38%)
FASTKD3	NP_076996.2	RESC6-like	129..457	CDD:480594	86/445 (19%)
		FAST_2	490..580	CDD:462448	23/95 (24%)
		RAP	593..650	CDD:214932	16/42 (38%)