DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31643 and K12C11.1

DIOPT Version :9

Sequence 1:	NP_001285652.1	Gene:	CG31643 / 318867	FlyBaseID:	FBgn0051643	Length:	899	Species:	Drosophila melanogaster
Sequence 2:	NP_490843.1	Gene:	K12C11.1 / 171704	WormBaseID:	WBGene00019673	Length:	498	Species:	Caenorhabditis elegans

Alignment Length:	413	Identity:	89/413 - (21%)
Similarity:	132/413 - (31%)	Gaps:	134/413 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   324 HQEPAALIEPLKKALEK---LLQEEGTADALFCAVP-FA--TPLQRDQYLHQFKELLYSEEAWQQ 382
            :.:...:.|.||:...|   ||:.|.|......|.| ||  ...|.|      .||||.|.|
Worm   123 NDKTTTIAEKLKELSAKHVYLLRAENTDSGDVLAEPKFAGSGDFQLD------TELLYKEMA--- 178

  Fly   383 PNASGHLFSVLRALKVSDIEFCNTYWSGVVKELESCPEKHL-------HLRFL-RHCQRYMNFNN 439
                     .||.:|.........|.|.:..|......||:       .|..| ||...|.....
Worm   179 ---------ELRVVKTEKEIGVMRYASKIASEAHRAAMKHMRPGLYEYQLESLFRHTSYYHGGCR 234

  Fly   440 NLGGT-------------YRHLELER----KLSRMCM-------NAIEHDIAGRLPA--KFARLA 478
            :|..|             |.|.....    |...||:       |....||....|:  ||....
Worm   235 HLAYTCIAATGCNGSVLHYGHANAPNDKFIKDGDMCLFDMGPEYNCYASDITTSFPSNGKFTEKQ 299

  Fly   479 SFVLAYGQTPLAWKKFPNFLLSKMLAM--APQLGIQDCFLLSRGMQIASELRFRQHLPALAGMQL 541
            ..|.             |.:|:..||:  |.:.|::     ...|.|.||....:||.. ||:.:
Worm   300 KIVY-------------NAVLAANLAVLKAAKPGVR-----WTDMHILSEKVILEHLKQ-AGLIV 345

  Fly   542 STMDSI----------------LIG-----CAERHLRDA-EKDPLNASELSMIVRTLSHRKKLKN 584
            ..:|..                |||     |. .::.|| .:..|...:.....|||..|..:
Worm   346 GDIDKAVEARVGAVFMPHGLGHLIGLDVHDCG-GYMGDATPRSTLPGLKSLRTTRTLMERMAI-- 407

  Fly   585 TV---------VYNQALA--------------QYKNLHCNDLNSRVVRDMAYNFNASNFFVPELL 626
            |:         :.|:|||              :|:......:...|:...:.|.|.|:  :|..:
Worm   408 TIEPGCYFIDFLLNEALADPKKSEFLVKSEIDKYRGSGGVRIEDDVIIRASGNENLSD--LPRTV 470

  Fly   627 ESMFAYISEQHDHVSGDTVEKVL 649
            |.:..:::.     .|:..|||:
Worm   471 EEIENFMAS-----GGEWTEKVI 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31643	NP_001285652.1	FAST_1	647..713	CDD:284217	2/3 (67%)
		FAST_2	736..816	CDD:285557
		RAP	834..894	CDD:214932
K12C11.1	NP_490843.1	AMP_N	12..152	CDD:198079	8/28 (29%)
K12C11.1	NP_490843.1	Prolidase	189..465	CDD:238520	59/297 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352329at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010