DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31636 and Clvs1

DIOPT Version :9

Sequence 1:	NP_001285685.1	Gene:	CG31636 / 318865	FlyBaseID:	FBgn0051636	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_001342112.1	Gene:	Clvs1 / 74438	MGIID:	1921688	Length:	354	Species:	Mus musculus

Alignment Length:	275	Identity:	77/275 - (28%)
Similarity:	132/275 - (48%)	Gaps:	43/275 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSVRPLNAALQEICIR----ELNELPARMAQDIEALRDWVLKQP---HLRACTDDQFLLAFLRG 58
            ::.:..|.|.|....|.    ||||.|..:.|||:.:||.::.:|   .||  |||.|:|.|||.
Mouse    20 LAKMTHLQAGLSPDTIEKARLELNENPDILHQDIQQVRDMIITRPDIGFLR--TDDAFILRFLRA 82

  Fly    59 TKFSLERAKEKFDRFYTLQRSIPEVFNERRL---------ATDPQVLDIVRM------GVLLQIP 108
            .||      .:.|.|    |.:.:.|..|:|         |.||   .|.|.      |||
Mouse    83 RKF------HQADAF----RLLAQYFQYRQLNLDMFKNFKADDP---GIKRALIDGFPGVL---- 130

  Fly   109 MDADDPGPRVTIIRAGSYDTSKHKFQDIIRVGSMFGEIMMFEDDNATVSGYVEIMDMAGVTGSHL 173
            .:.|..|.::.::.|.::|.|::.|.||:|...:..|::: ||....::|::.|:|.:..:....
Mouse   131 ENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLI-EDPELQINGFILIIDWSNFSFKQA 194

  Fly   174 FALQPQLLSKFSTYADEAMPTRQKGIHFINVPAAFETGFNSLRSFFPAKIKSRISV-SSDPAAIY 237
            ..|.|.:|........::.|.|..|:||:|.|......:..::.|...|.:.||.: .::..:::
Mouse   195 SKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLH 259

  Fly   238 ELVRRKYLPQEYGGT 252
            :|:..::||.|:|||
Mouse   260 QLIHPEFLPSEFGGT 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31636	NP_001285685.1	CRAL_TRIO_N	27..72	CDD:215024	18/47 (38%)
CG31636	NP_001285685.1	SEC14	96..252	CDD:238099	39/162 (24%)
Clvs1	NP_001342112.1	CRAL_TRIO_N	51..97	CDD:215024	21/57 (37%)
		CRAL_TRIO	125..274	CDD:366224	37/153 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	317..354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835970
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4693
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.790