DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31636 and Sec14l1

DIOPT Version :9

Sequence 1:	NP_001285685.1	Gene:	CG31636 / 318865	FlyBaseID:	FBgn0051636	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_083053.2	Gene:	Sec14l1 / 74136	MGIID:	1921386	Length:	719	Species:	Mus musculus

Alignment Length:	280	Identity:	57/280 - (20%)
Similarity:	97/280 - (34%)	Gaps:	86/280 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LQEICIRELNELPARMAQDIEALRDWVLKQPHLRACTDDQFLLAFLRGTKFSLERAKEKFDRFYT 75
            |||.|:..              ||.| |::.|......|:.:|.|||...|::::|:|...:..|
Mouse   254 LQESCLIR--------------LRQW-LQETHKGKIPKDEHILRFLRARDFNIDKAREIMCQSLT 303

  Fly    76 --LQRSIPEVFNERRLATDPQVLDIVRMGVLLQIPMD--------ADDPGPRVTIIRAGSYDTSK 130
              .|..:..:.:   ..|.||||            :|        .|..|..:.::|.|..||
Mouse   304 WRKQHQVDYILD---TWTPPQVL------------LDYYAGGWHHHDKDGRPLYVLRLGQMDT-- 351

  Fly   131 HKFQDIIRVGSMFGEIMMFE-------------DDNATV-----SGYVEIMDMAGVTGSHLFALQ 177
               :.::|.   .||..:..             ::|..|     |.:..::|:.|:...||:...
Mouse   352 ---KGLVRA---LGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPG 410

  Fly   178 PQLLSKFSTYADEAMPTRQKGIHFINVPAAFETGFNSLRSFFPAKIKSRISVSSDPAAIYELVRR 242
            .:.|.:.....:...|.....:..:..|..|...:..:..|                 |.:..||
Mouse   411 VKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPF-----------------IDDNTRR 458

  Fly   243 KYL---PQEYGGTGGNLQDI 259
            |:|   ..:|.|.||.|..|
Mouse   459 KFLIYAGNDYQGPGGLLDYI 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31636	NP_001285685.1	CRAL_TRIO_N	27..72	CDD:215024	13/44 (30%)
CG31636	NP_001285685.1	SEC14	96..252	CDD:238099	29/184 (16%)
Sec14l1	NP_083053.2	Required for interaction and inhibitory function toward DDX58. /evidence=ECO:0000250\|UniProtKB:Q92503	1..510		57/280 (20%)
		PRELI	17..173	CDD:282550
		CRAL_TRIO_N	256..301	CDD:215024	15/59 (25%)
		CRAL_TRIO	326..490	CDD:279044	32/178 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900