DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31636 and Sec14l5

DIOPT Version :9

Sequence 1:	NP_001285685.1	Gene:	CG31636 / 318865	FlyBaseID:	FBgn0051636	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_001129182.2	Gene:	Sec14l5 / 287060	RGDID:	1564638	Length:	696	Species:	Rattus norvegicus

Alignment Length:	323	Identity:	55/323 - (17%)
Similarity:	113/323 - (34%)	Gaps:	76/323 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LNAALQEICIRELNELPARMAQDIEALRDWVLKQPHLRACTDDQFLLAFLRGTKFSLERAKEKFD 71
            |:|...|.|:..|:.:   ....:..||.| |::.|......|:.:|.|||...|.|::|::...
  Rat   226 LDADYIERCLGHLSPM---QESCLVQLRRW-LQETHKGKIPKDEHILRFLRARDFHLDKARDMLC 286

  Fly    72 RFYTLQRSIPEVFNERRLATDPQVLDIVRMGVLLQ-----IPMD---------ADDPGPRVTIIR 122
            :..:.::.                   .::.:|||     .|:.         .|..|..:.|:|
  Rat   287 QSLSWRKQ-------------------HQVDLLLQTWRPPAPLQEFYAGGWHYQDIDGRPLYILR 332

  Fly   123 AGSYDT--------SKHKFQDIIRVGS-----------MFGEIMMFEDDNATVSGYVEIMDMAGV 168
            .|..||        .:...|.::.|..           .||.         .:|.:..::|:.|:
  Rat   333 LGQMDTKGLMKAVGEEALLQHVLSVNEEGQKRCEGNTRQFGR---------PISSWTCLLDLEGL 388

  Fly   169 TGSHLFALQPQLLSKFSTYADEAMPTRQKGIHFINVPAAFETGFNSLRSFFPAKIKSRISVSS-- 231
            ...||:....:.|.:.....::..|.....:..:..|..|...:..:..|.....:.:..:.|
  Rat   389 NMRHLWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINENTRRKFLIYSGS 453

  Fly   232 ---DPAAIYELVRRKYLPQEYGGTGGNLQDISHTMEAKLSSYGPYFRESQNFGANDKLREFGD 291
               .|..:.:.:.:..:|...||     :.:.:..|..:.....|..|.:...| |:||::.:
  Rat   454 NYQGPGGLVDYLDKDVIPDFLGG-----ESVCNVPEGGMVPKSLYLTEEEQEQA-DQLRQWSE 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31636	NP_001285685.1	CRAL_TRIO_N	27..72	CDD:215024	13/44 (30%)
CG31636	NP_001285685.1	SEC14	96..252	CDD:238099	29/193 (15%)
Sec14l5	NP_001129182.2	PRELI	17..173	CDD:309720
		Amidase	<179..309	CDD:327489	21/105 (20%)
		CRAL_TRIO_N	243..288	CDD:215024	13/45 (29%)
		CRAL_TRIO	314..477	CDD:306996	26/176 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900