Protein Alignment CG31636 and CLVS1

DIOPT Version :10

• Sequence 1: NP_723200.1
• Gene: CG31636 / 318865
• FlyBaseID: FBgn0051636
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: NP_775790.1
• Gene: CLVS1 / 157807
• HGNCID: 23139
• Length: 354
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 77/275 - (28%)
• Similarity: 132/275 - (48%)
• Gaps: 43/275 - (15%)

  Fly     1 MSSVRPLNAALQEICIR----ELNELPARMAQDIEALRDWVLKQP---HLRACTDDQFLLAFLRG 58
            ::.:..|.|.|....|.    ||||.|..:.|||:.:||.::.:|   .||  |||.|:|.|||.
Human    20 LAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMIITRPDIGFLR--TDDAFILRFLRA 82

  Fly    59 TKFSLERAKEKFDRFYTLQRSIPEVFNERRL---------ATDPQVLDIVRM------GVLLQIP 108
            .||      .:.|.|    |.:.:.|..|:|         |.||   .|.|.      |||
Human    83 RKF------HQADAF----RLLAQYFQYRQLNLDMFKNFKADDP---GIKRALIDGFPGVL---- 130

  Fly   109 MDADDPGPRVTIIRAGSYDTSKHKFQDIIRVGSMFGEIMMFEDDNATVSGYVEIMDMAGVTGSHL 173
            .:.|..|.::.::.|.::|.|::.|.||:|...:..|::: ||....::|::.|:|.:..:....
Human   131 ENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLI-EDPELQINGFILIIDWSNFSFKQA 194

  Fly   174 FALQPQLLSKFSTYADEAMPTRQKGIHFINVPAAFETGFNSLRSFFPAKIKSRISV-SSDPAAIY 237
            ..|.|.:|........::.|.|..|:||:|.|......:..::.|...|.:.||.: .::..:::
Human   195 SKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLH 259

  Fly   238 ELVRRKYLPQEYGGT 252
            :|:..::||.|:|||
Human   260 QLIHPEFLPSEFGGT 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31636	NP_723200.1	CRAL_TRIO_N	27..72	CDD:215024	18/47 (38%)
		SEC14	115..252	CDD:469559	33/137 (24%)
CLVS1	NP_775790.1	CRAL_TRIO_N	51..97	CDD:215024	21/57 (37%)
		SEC14	123..274	CDD:469559	37/155 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	333..354