DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31636 and Sec14l2

DIOPT Version :9

Sequence 1:	NP_001285685.1	Gene:	CG31636 / 318865	FlyBaseID:	FBgn0051636	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_446253.2	Gene:	Sec14l2 / 116486	RGDID:	621779	Length:	403	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	67/296 - (22%)
Similarity:	110/296 - (37%)	Gaps:	88/296 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 DDQFLLAFLRGTKFSLERA-----------KEK-FDRFYTLQRSIPEVFNE----RRLATD---- 92
            ||.|||.:||...|.|:::           |:| .|:..:.|.  |||..:    .|...|
  Rat    34 DDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDKIISWQP--PEVIQQYLSGGRCGYDLDGC 96

  Fly    93 PQVLDIVRMGVLLQIPMDADDPGPRVTIIRAGSYDTSKHKFQDIIRVGSMFGEIMMFEDDNAT-- 155
            |...||:.       |:||          :...:..||   ||::|......|:::.|..:.|
  Rat    97 PVWYDIIG-------PLDA----------KGLLFSASK---QDLLRTKMRDCELLLQECTHQTAK 141

  Fly   156 ----VSGYVEIMDMAGVTGSHLFALQPQLLSKFSTYADEAMPTRQKGIHFINVPAAFETGFNSLR 216
                :.....|.|..|:...||:....:...:|.|..:|..|...|.:..:..|..|...:|.::
  Rat   142 LGKKIETITMIYDCEGLGLKHLWKPAVEAYGEFLTMFEENYPETLKRLFVVKAPKLFPVAYNLIK 206

  Fly   217 SFFPAKIKSRISVSSDPAAIYELVRRKY-----LPQEYGGT----GGNLQDISHTMEAKLSSYGP 272
            .|.....:.:|.|.   .|.::.|..|:     ||.|||||    .||                |
  Rat   207 PFLSEDTRKKIMVL---GANWKEVLLKHISPDQLPVEYGGTMTDPDGN----------------P 252

  Fly   273 YFRESQNFGAN--------DKLREFGDH----KRGN 296
            ..:...|:|.:        |::::..:|    .||:
  Rat   253 KCKSKINYGGDIPKQYYVRDQVKQQYEHSVQISRGS 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31636	NP_001285685.1	CRAL_TRIO_N	27..72	CDD:215024	11/35 (31%)
CG31636	NP_001285685.1	SEC14	96..252	CDD:238099	37/166 (22%)
Sec14l2	NP_446253.2	CRAL_TRIO_N	13..59	CDD:215024	9/24 (38%)
		SEC14	76..244	CDD:214706	43/192 (22%)
		GOLD_2	300..381	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900