DRSC/TRiP Functional Genomics Resources

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Protein Alignment dtr and NUD1

DIOPT Version :9

Sequence 1:NP_724335.2 Gene:dtr / 318856 FlyBaseID:FBgn0023090 Length:1483 Species:Drosophila melanogaster
Sequence 2:NP_015018.3 Gene:NUD1 / 854555 SGDID:S000005900 Length:851 Species:Saccharomyces cerevisiae


Alignment Length:264 Identity:70/264 - (26%)
Similarity:106/264 - (40%) Gaps:56/264 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MSNSNRKEITGLNRMTPKGLKELCKKDKLYQTPRLNDVLYLHYQGFQCIESL-EEYTELKCLWLE 64
            :|....|.:.|:.|:.|..|                 ||.|.......:|.: ....:|.|   .
Yeast   484 LSRGKLKNMFGMQRLLPNVL-----------------VLNLSDNEMNTLEGIPSNVVQLFC---S 528

  Fly    65 CNAISEIQ-GLEKLSKLKCLFLQNNLI-TKIENLDPCRELDTLNLSSNHIRKIQNIGTNVLPVLN 127
            .|.|:... .|.....|:||.|..||: |.::.|..|..|..:|||.|.|:.::.||::.:..||
Yeast   529 NNKITSAHCSLAGFHDLECLDLSYNLLNTSLKFLSLCHHLQEVNLSYNSIQSLEGIGSSRMKKLN 593

  Fly   128 TLTISSNYLKDSESLSDLIQCK--------TLSVLDLSNNRIDDILIVKIFEQMLNLKVLVLQGN 184
               :|:|.:........||...        |:.|||||||   :|:.|:....:..||||.|.||
Yeast   594 ---LSNNEINGIIDFEQLILTNNSVVGGWLTVEVLDLSNN---NIIGVRNINCLPRLKVLNLNGN 652

  Fly   185 PVVS------------RLPQYRKTLILACKELTY-LDSRPVFPRDRACAEAWKRDGYEGERKENN 236
            |:||            |....:.|.....|...| ||.:..||...  .:..|.||:    .:.:
Yeast   653 PLVSIVESSKMENGTLRALSIKNTGGALSKLQNYKLDDQFTFPYQN--LKILKLDGF----AQLS 711

  Fly   237 RWNR 240
            :|.:
Yeast   712 KWQK 715

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dtrNP_724335.2 leucine-rich repeat 38..57 CDD:275380 4/19 (21%)
LRR_8 56..112 CDD:290566 19/57 (33%)
LRR_4 56..98 CDD:289563 13/43 (30%)
LRR_RI 58..>184 CDD:238064 43/135 (32%)
leucine-rich repeat 58..79 CDD:275380 5/21 (24%)
leucine-rich repeat 80..101 CDD:275380 9/21 (43%)
LRR_8 100..161 CDD:290566 22/68 (32%)
leucine-rich repeat 102..125 CDD:275380 8/22 (36%)
leucine-rich repeat 126..147 CDD:275380 5/20 (25%)
leucine-rich repeat 151..175 CDD:275380 9/23 (39%)
NUD1NP_015018.3 LRR <440..662 CDD:227223 58/203 (29%)
leucine-rich repeat 522..544 CDD:275380 5/24 (21%)
leucine-rich repeat 545..567 CDD:275380 9/21 (43%)
PPP1R42 557..784 CDD:411060 49/171 (29%)
leucine-rich repeat 568..588 CDD:275380 8/19 (42%)
leucine-rich repeat 589..621 CDD:275380 6/34 (18%)
leucine-rich repeat 622..643 CDD:275380 9/23 (39%)
leucine-rich repeat 699..738 CDD:275380 4/21 (19%)
leucine-rich repeat 739..768 CDD:275380
leucine-rich repeat 794..806 CDD:275378
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4530
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

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