DRSC/TRiP Functional Genomics Resources

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Protein Alignment His2A:CG31618 and MACROH2A1

DIOPT Version :10

Sequence 1:NP_724343.1 Gene:His2A:CG31618 / 318855 FlyBaseID:FBgn0051618 Length:124 Species:Drosophila melanogaster
Sequence 2:NP_613258.2 Gene:MACROH2A1 / 9555 HGNCID:4740 Length:372 Species:Homo sapiens


Alignment Length:123 Identity:79/123 - (64%)
Similarity:93/123 - (75%) Gaps:2/123 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MSGRGKGGKVKGKAKSRSNRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLEL 65
            ||.|  |||.|....|||.:||:.|||||:.|.::||:...|:|.|||||:|||:|||.||:|||
Human     1 MSSR--GGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILEL 63

  Fly    66 AGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKK 123
            ||||||||||.|:.|||:.||:.||||||:||.|||||.|||||||...||.||...|
Human    64 AGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSK 121

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
His2A:CG31618NP_724343.1 PTZ00017 16..124 CDD:185399 72/108 (67%)
MACROH2A1NP_613258.2 H2A 14..119 CDD:197711 71/104 (68%)
Macro_H2A-like 178..368 CDD:394875
Blue background indicates that the domain is not in the aligned region.

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