Protein Alignment Bsg and BSG

DIOPT Version :9

• Sequence 1: NP_723346.2
• Gene: Bsg / 318841
• FlyBaseID: FBgn0261822
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001719.2
• Gene: BSG / 682
• HGNCID: 1116
• Length: 385
• Species: Homo sapiens
• Alignment Length: 390
• Identity: 98/390 - (25%)
• Similarity: 154/390 - (39%)
• Gaps: 106/390 - (27%)

  Fly   334 GASGEQTTISAATSTRAMMGG---------GGGVAGAGFSAGASGPMLGAGGHMLMGGQGHQVHL 389
            ||||....:.|..|.:..:||         |..|....:.....||. .....:..|.:..:||:
Human    18 GASGAAGFVQAPLSQQRWVGGSVELHCEAVGSPVPEIQWWFEGQGPN-DTCSQLWDGARLDRVHI 81

  Fly   390 Q---HQ-TLLPVKMDKLV-----------PNYDNAEH-----QMKFY------------------ 416
            .   || ....:.:|.||           .|..:..|     ::|:.
Human    82 HATYHQHAASTISIDTLVEEDTGTYECRASNDPDRNHLTRAPRVKWVRAQAVVLVLEPGTVFTTV 146

  Fly   417 -DIRSPLVLSCNVKD-GTPGGVLIWKKNGTAVTD--VPSLRGRFKLIADENKFIIDKTDTNDD-G 476
             |:.|.::|:|::.| .|......|.|.|..:.:  :|..:..||:            |::|. |
Human   147 EDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKV------------DSDDQWG 199

  Fly   477 KYSCEFDGVSKEIEVIARV-------VVRVPSNTAVVEGEKMSVTCSVVGTKPELTWTFANVT-- 532
            :|||.|   ..|....|.:       |..|.|:..:.|||...:.|......|...|.:..:|
Human   200 EYSCVF---LPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDS 261

  Fly   533 ----LTNATD-RFILKPDDNGVPNAILTLDNVTLD-DRGEYKCIGRNAANVYGGNTTTPASD--V 589
                |.|.:: ||.:.....   .:.|.::|:.:: |.|:|:|.|          |::..||  :
Human   262 EDKALMNGSESRFFVSSSQG---RSELHIENLNMEADPGQYRCNG----------TSSKGSDQAI 313

  Fly   590 TTVRVKGKFAALWPFLGICAEVLILCIIILIYEKRRNKSELEESD--------TDPQEQKKKRRN 646
            .|:||:...|||||||||.||||:|..||.||||||...::.:.|        :..|.|..|.:|
Human   314 ITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKN 378

  Fly   647  646
            Human   379  378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bsg	NP_723346.2	IG_like	420..497	CDD:214653	20/87 (23%)
		Ig	423..497	CDD:299845	19/84 (23%)
		IG_like	500..583	CDD:214653	19/90 (21%)
		Ig	512..575	CDD:143165	15/70 (21%)
BSG	NP_001719.2	IG_like	29..113	CDD:214653	15/84 (18%)
		Ig	40..114	CDD:143165	13/74 (18%)
		Essential for interaction with KDR/VEGFR2. /evidence=ECO:0000269|PubMed:25825981	195..199		1/3 (33%)
		Ig	219..317	CDD:299845	25/110 (23%)
		IG_like	228..318	CDD:214653	23/102 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	353..385		5/26 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157444
Domainoid	1	1.000	60	1.000	Domainoid score	I10589
eggNOG	1	0.900	-	-		E1_28H7W
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto91258
orthoMCL	1	0.900	-	-		OOG6_107774
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1696
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.600