DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bsg and Nptn

DIOPT Version :9

Sequence 1:	NP_723346.2	Gene:	Bsg / 318841	FlyBaseID:	FBgn0261822	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	XP_006243234.1	Gene:	Nptn / 56064	RGDID:	620296	Length:	397	Species:	Rattus norvegicus

Alignment Length:	247	Identity:	77/247 - (31%)
Similarity:	110/247 - (44%)	Gaps:	47/247 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   421 PLVLSCNVKDGTPGGVLI---WKKNGTAVTDVPSLRGRFKLIADENKFIIDKTDTNDDGKYSCEF 482
            |:.|.||:...:  ..|:   |.|||..:|..       :..|...::.|:|....|.|:|.|.:
  Rat   164 PVTLQCNLTSSS--HTLMYSYWTKNGVELTAT-------RKNASNMEYRINKPRAEDSGEYHCVY 219

  Fly   483 DGVS-----KEIEVIARVVVRVPSNTA------VVEGEKMSVTCSVVG-TKPELTW------TFA 529
            ..||     ..|||.|     .|..|.      ..||:...:.|..|| ..||..|      .|.
  Rat   220 HFVSAPKANATIEVKA-----APDITGHKRSENKNEGQDAMMYCKSVGYPHPEWMWRKKENGVFE 279

  Fly   530 NVTLTNATDRFILKPDDNGVPNAILTLDNVTLDDRGEYKCIGRNAANVYGGNTTTPASDVTTVRV 594
            .:  :|::.||.:...:|.....|:.| .:| :|.|||:|   ||.|..|.     ||..|.:||
  Rat   280 EI--SNSSGRFFIINKENYTELNIVNL-QIT-EDPGEYEC---NATNSIGS-----ASVSTVLRV 332

  Fly   595 KGKFAALWPFLGICAEVLILCIIILIYEKRRNKSELEESDTDPQEQKKKRRN 646
            :...|.|||||||.||::||.:||::||||:...|:.:.|......|....|
  Rat   333 RSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEPAGPMKTNSTN 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bsg	NP_723346.2	IG_like	420..497	CDD:214653	23/83 (28%)
		Ig	423..497	CDD:299845	22/81 (27%)
		IG_like	500..583	CDD:214653	27/95 (28%)
		Ig	512..575	CDD:143165	20/69 (29%)
Nptn	XP_006243234.1	Ig	31..146	CDD:416386
		Ig strand A	32..36	CDD:409353
		Ig strand A'	37..43	CDD:409353
		Ig strand B	46..55	CDD:409353
		Ig strand C	60..68	CDD:409353
		Ig strand C'	73..77	CDD:409353
		Ig strand D	87..93	CDD:409353
		Ig strand E	96..105	CDD:409353
		Ig strand F	112..120	CDD:409353
		Ig strand G	136..146	CDD:409353
		Ig	167..218	CDD:416386	15/59 (25%)
		Ig strand C	179..184	CDD:409353	0/4 (0%)
		Ig strand E	200..204	CDD:409353	0/3 (0%)
		Ig strand F	214..218	CDD:409353	1/3 (33%)
		Ig	249..332	CDD:416386	28/94 (30%)
		Ig strand B	252..261	CDD:409353	1/8 (13%)
		Ig strand C	266..272	CDD:409353	3/5 (60%)
		Ig strand C'	275..277	CDD:409353	0/1 (0%)
		Ig strand D	288..293	CDD:409353	1/4 (25%)
		Ig strand E	296..304	CDD:409353	1/7 (14%)
		Ig strand F	312..319	CDD:409353	5/9 (56%)
		Ig strand G	322..332	CDD:409353	4/14 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351413
Domainoid	1	1.000	57	1.000	Domainoid score	I10630
eggNOG	1	0.900	-	-		E1_28H7W
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1696
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.700