DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bsg and cd22

DIOPT Version :9

Sequence 1:	NP_723346.2	Gene:	Bsg / 318841	FlyBaseID:	FBgn0261822	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	NP_001077292.1	Gene:	cd22 / 554810	ZFINID:	ZDB-GENE-050522-521	Length:	417	Species:	Danio rerio

Alignment Length:	318	Identity:	69/318 - (21%)
Similarity:	113/318 - (35%)	Gaps:	92/318 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   373 GAGGHMLMGGQGHQVHLQHQTLLPVKMDKLVPNYDNAEHQMKFYDIRSPLVLSCNVKDGTP-GGV 436
            |:||..|           ...:||:   :::.....|..|:   |....:.|:|:.::.|| ...
Zfish   128 GSGGIQL-----------KVAVLPL---RVIVKTQKASEQI---DEGDSVTLTCSAENCTPTEES 175

  Fly   437 LIWKKNGTAVTDVPSLRGRFKLIADENKFIIDKTDTNDDGKYSCEFDGVSKEIEVIARVVVR--- 498
            .:|.||...   :|...|        |:..|.....:|.|.|||.....:..:.....:.||
Zfish   176 FLWFKNHLL---LPQATG--------NELRISSVSHSDAGNYSCGLKNTNTTLSAQTLLDVRYQP 229

  Fly   499 ------VPSNTAVVEGEKMSVTCSVVGTKPELT---W---TFANVTLTNATDRFILKPDDNGVPN 551
                  |.|:..:.||..:::||. ....|.:|   |   |.||::...:              .
Zfish   230 KDVEISVSSSEEIQEGNPLTLTCK-SKANPAVTHYSWFKITDANMSSVGS--------------G 279

  Fly   552 AILTLDNVTLDDRGEYKCIGRNAANVYGGNTTTPASDVTTVRVKGK----FAALWPFLGICAEVL 612
            :.||:.:.:|.|.|.|.|   .|.|..|    |..|.|..::|...    .:|...||.:.|.:|
Zfish   280 SELTIRSASLQDAGLYFC---TATNHIG----TQKSTVKALKVASDRHFLLSASAVFLFVMAMLL 337

  Fly   613 ILCIII---------------------LIYEK-RRNKSELEESDTDPQEQKKKRRNYD 648
            :|.::.                     :|||. |:.:||...|.....:.|....|.|
Zfish   338 VLFVLFVRKKLFTSQKQTAEQMPAVTEVIYENLRKTESETNTSTVIYADLKLPPSNSD 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bsg	NP_723346.2	IG_like	420..497	CDD:214653	16/77 (21%)
		Ig	423..497	CDD:299845	16/74 (22%)
		IG_like	500..583	CDD:214653	21/88 (24%)
		Ig	512..575	CDD:143165	15/68 (22%)
cd22	NP_001077292.1	Ig	19..122	CDD:299845
		IG_like	25..136	CDD:214653	4/18 (22%)
		IG_like	156..225	CDD:214653	16/79 (20%)
		IGc2	156..208	CDD:197706	14/62 (23%)
		IG_like	237..315	CDD:214653	24/99 (24%)
		IGc2	244..304	CDD:197706	19/77 (25%)
		MSC	<307..386	CDD:286487	16/78 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910