DRSC/TRiP Functional Genomics Resources

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Protein Alignment Bsg and CDON

DIOPT Version :9

Sequence 1:NP_723346.2 Gene:Bsg / 318841 FlyBaseID:FBgn0261822 Length:648 Species:Drosophila melanogaster
Sequence 2:NP_001230526.1 Gene:CDON / 50937 HGNCID:17104 Length:1287 Species:Homo sapiens


Alignment Length:600 Identity:109/600 - (18%)
Similarity:169/600 - (28%) Gaps:252/600 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 LASALSFLSIFLAIYAQSLANDLSKESTEFEESPTIYYGDPVVNLGQPFSITCII-PITDQIHWL 69
            |....:.|.:.|.|...|:::||   :..|...|.    ..|..||.|..:.|.. |:|.:|.||
Human     5 LGPLCTLLYVTLTILCSSVSSDL---APYFTSEPL----SAVQKLGGPVVLHCSAQPVTTRISWL 62

  Fly    70 KNGEPITRHNLRHGRDDHAYVLSESAIEGEKHKIEAHLSVRHALKVHE---GRYQC--NRRRGSY 129
            .||:                     .::|....::.|......|.::.   |.|||  |...|:.
Human    63 HNGK---------------------TLDGNLEHVKIHQGTLTILSLNSSLLGYYQCLANNSIGAI 106

  Fly   130 ILHVRDPKGVGAG-------------AGEPTESGY--QTIDELTPNSADDFFTRA-WLEQQQQQQ 178
               |..|..|...             ..|...:|:  ..:.|..|.:...:..|. |||...:..
Human   107 ---VSGPATVSVAVLGDFGSSTKHVITAEEKSAGFIGCRVPESNPKAEVRYKIRGKWLEHSTENY 168

  Fly   179 QLPHQSHKLHKSHLGYGNASLSGSQPWHPSAGGGGIHRVYSATPPDFPPPRLNLLEQTVAPPEPP 243
            .:      |...:|...|.||.....:..:|                                  
Human   169 LI------LPSGNLQILNVSLEDKGSYKCAA---------------------------------- 193

  Fly   244 TILYNPNPTHPTASATATETSVLLTTAHHHAHHQQQLQQQSQHTLNAFQLPLPPRPNPGQNERYQ 308
               ||| .||                         ||:                           
Human   194 ---YNP-VTH-------------------------QLK--------------------------- 202

  Fly   309 TYAPHYVPPVVVSGAGAGAGADPGAGASGEQTTISAATSTRAMMGGGGGVAGAGFSAGASGPMLG 373
                  |.|:                  |.:..:|..:|...                       
Human   203 ------VEPI------------------GRKLLVSRPSSDDV----------------------- 220

  Fly   374 AGGHMLMGGQGHQVHLQHQTLLPVKMDKLVPNYDNAEHQMKFYDIRSPLVLSCNVKDGTPGGVLI 438
               |:|     |..|.|...:|.                      |||:.|.| |..|.|...:.
Human   221 ---HIL-----HPTHSQALAVLS----------------------RSPVTLEC-VVSGVPAPQVY 254

  Fly   439 WKKNGTAVTDVPSLRGRFKLIADENKFIIDKTDTNDDGKYSCEFDGVSKEIEVIARVVVRVPSNT 503
            |.|:|..:....:.|..:..:|      .|..|..|.|.|||.....|.:::.:. .:|.|..:.
Human   255 WLKDGQDIAPGSNWRRLYSHLA------TDSVDPADSGNYSCMAGNKSGDVKYVT-YMVNVLEHA 312

  Fly   504 AVVEGEKMSV---------TCSVVGT-KPELTWTFANVTLTNATDRFILKPDDNGVPNAILTLDN 558
            ::.:|.:..:         ||.|.|. .|..|| |.|....:.:.|.:..  .||     |.:..
Human   313 SISKGLQDQIVSLGATVHFTCDVHGNPAPNCTW-FHNAQPIHPSARHLTA--GNG-----LKISG 369

  Fly   559 VTLDDRGEYKCIGRN 573
            ||::|.|.|:|:..|
Human   370 VTVEDVGMYQCVADN 384

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BsgNP_723346.2 IG_like 420..497 CDD:214653 20/76 (26%)
Ig 423..497 CDD:299845 18/73 (25%)
IG_like 500..583 CDD:214653 20/83 (24%)
Ig 512..575 CDD:143165 19/71 (27%)
CDONNP_001230526.1 Ig 30..115 CDD:299845 26/112 (23%)
IG_like 41..115 CDD:214653 23/97 (24%)
Ig 139..195 CDD:299845 12/98 (12%)
IG_like 141..195 CDD:214653 12/96 (13%)
IGc2 237..297 CDD:197706 19/66 (29%)
IG_like 319..397 CDD:214653 19/73 (26%)
IGc2 326..387 CDD:197706 19/66 (29%)
I-set 405..517 CDD:254352
Ig 422..514 CDD:143165
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 531..553
FN3 577..673 CDD:238020
FN3 721..811 CDD:238020
FN3 836..923 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 933..955
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1268..1287
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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