DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bsg and Nptn

DIOPT Version :9

Sequence 1:	NP_723346.2	Gene:	Bsg / 318841	FlyBaseID:	FBgn0261822	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	XP_006510945.1	Gene:	Nptn / 20320	MGIID:	108077	Length:	397	Species:	Mus musculus

Alignment Length:	247	Identity:	76/247 - (30%)
Similarity:	111/247 - (44%)	Gaps:	47/247 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   421 PLVLSCNVKDGTPGGVLI---WKKNGTAVTDVPSLRGRFKLIADENKFIIDKTDTNDDGKYSCEF 482
            |:.|.||:...:  ..|:   |.:||..:|..       :..|...::.|:|....|.|:|.|.:
Mouse   164 PVTLQCNLTSSS--HTLMYSYWTRNGVELTAT-------RKNASNMEYRINKPRAEDSGEYHCVY 219

  Fly   483 DGVS-----KEIEVIARVVVRVPSNTA------VVEGEKMSVTCSVVG-TKPELTW------TFA 529
            ..||     ..|||.|     .|..|.      ..||:...:.|..|| ..||..|      .|.
Mouse   220 HFVSAPKANATIEVKA-----APDITGHKRSENKNEGQDAMMYCKSVGYPHPEWIWRKKENGVFE 279

  Fly   530 NVTLTNATDRFILKPDDNGVPNAILTLDNVTLDDRGEYKCIGRNAANVYGGNTTTPASDVTTVRV 594
            .:  :|::.||.:...:|....:|:.| .:| :|.|||:|   ||.|..|.     ||..|.:||
Mouse   280 EI--SNSSGRFFITNKENYTELSIVNL-QIT-EDPGEYEC---NATNSIGS-----ASVSTVLRV 332

  Fly   595 KGKFAALWPFLGICAEVLILCIIILIYEKRRNKSELEESDTDPQEQKKKRRN 646
            :...|.|||||||.||::||.:||::||||:...|:.:.|......|....|
Mouse   333 RSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEPAGPMKTNSTN 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bsg	NP_723346.2	IG_like	420..497	CDD:214653	22/83 (27%)
		Ig	423..497	CDD:299845	21/81 (26%)
		IG_like	500..583	CDD:214653	27/95 (28%)
		Ig	512..575	CDD:143165	20/69 (29%)
Nptn	XP_006510945.1	Ig	48..121	CDD:319273
		Ig	167..218	CDD:386229	14/59 (24%)
		Ig	249..332	CDD:386229	28/94 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847849
Domainoid	1	1.000	57	1.000	Domainoid score	I10828
eggNOG	1	0.900	-	-		E1_28H7W
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5184
SonicParanoid	1	1.000	-	-		X1696
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.730