DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Bsg and hmcn2

DIOPT Version :9

Sequence 1:NP_723346.2 Gene:Bsg / 318841 FlyBaseID:FBgn0261822 Length:648 Species:Drosophila melanogaster
Sequence 2:XP_031747766.1 Gene:hmcn2 / 100490941 XenbaseID:XB-GENE-6034990 Length:4625 Species:Xenopus tropicalis


Alignment Length:650 Identity:132/650 - (20%)
Similarity:210/650 - (32%) Gaps:200/650 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 PTIYYGD----PVVNLGQPFSITCI---IPITDQIHWLKNGEPITRHNLRHGRDDHAYVLSESAI 96
            |.:..|:    ..|....|..::|.   .| |..|.||:|     .|:|.|  :|...||:...:
 Frog  1707 PKVVIGEGSEHVTVTANDPLDLSCHATGYP-TPTIQWLRN-----NHSLSH--EDGVEVLNGGKM 1763

  Fly    97 EGEKHKIEAHLSVRHALKVHEGRYQCNRRRGSYILHVRDPKGVGAGAGEPTESGYQTIDELTPNS 161
                      |::|.....|.|:|:|.....|             |..|                
 Frog  1764 ----------LTIRQIQPEHAGKYKCKAEGDS-------------GTAE---------------- 1789

  Fly   162 ADDFFTRAWLEQQQQQQQLPHQS---------HKLHKSHLGYGNASLSGSQP-----WHPS---- 208
                   ||:|  .:.|:||..:         :.|.:..|   ...:|||.|     |...    
 Frog  1790 -------AWVE--VEVQELPSVTIAGGTTMVVNFLKRVVL---ECDVSGSPPPSVTWWKDGFLLP 1842

  Fly   209 --------------------------AGGGGIHRVYSA-TPPDFPPPRLNLLEQTVAPPEPPTI- 245
                                      ||.|....|.:. ..|:..|..:|   |||....|.:. 
 Frog  1843 VQGPKLQIDSVSIDDEGVYTCVATNFAGEGRQDVVLTVLVSPNIEPSDVN---QTVIENLPASFE 1904

  Fly   246 -LYNPNPTHPTASATATETSVLLTTAHHHAHHQQQLQQQSQHTLNAFQLPLPPRPNPGQNERYQT 309
             |.:.:|. |..|....|..:.........:..:.||.:|..:.::.:.........|..|....
 Frog  1905 CLASGSPL-PLVSWYRGEQLLSAAPGITLLNEGKTLQIESAKSSDSGEYRCVASNTAGSTELQYN 1968

  Fly   310 YAPHYVPPVVVS--------------GAGAGAGADPGAGASGEQTTISAATSTRAMMGGG----- 355
            ...:..|.:|..              ...|....:|......:|..:|.|.:...:|..|     
 Frog  1969 LLVNVAPRIVSMMDFATFLVNEQVWLECNATGVPEPAIMWLKDQVPVSTAIAGLQIMEQGRILSL 2033

  Fly   356 --GGVAGAG-FSAGASGPMLGAGGHMLMGGQGHQVHLQHQTLLPVKMDKLVPNYDNAEHQMKFYD 417
              ..|:.:| :|..|..|         .|...|.:.||          ..||.....|.......
 Frog  2034 RAAHVSDSGIYSCVAVNP---------AGEDSHHIALQ----------VFVPPTIMGEELNSSIA 2079

  Fly   418 IRSPLVLSCNVKDGTPGGVLIWKKNGTAVTDVPSLRGRFKLIADENKFI-IDKTDTNDDGKYSCE 481
            :..||:|.|. ....|..::.|.|:|..:...|.::     :.|:..:: ||:....|.|:|:||
 Frog  2080 VNQPLLLECQ-STAIPPPLITWLKDGRPLLQRPGVQ-----VIDDGHYLQIDQAQLRDAGRYTCE 2138

  Fly   482 FDGVSKEIEVIARVVVRVP--------SNTAVVEGEKMSVTCSVVGT-KPELTWTFANVTLTNAT 537
            ....:...|....|::.||        .:.:::||:.:|.||...|. .|.||||...:.||   
 Frog  2139 ASNDAGRTEKHYNVIIWVPPSFPEPSAPHHSIIEGQPVSFTCECTGVPPPTLTWTKNGLPLT--- 2200

  Fly   538 DRFILKPDDNGVPNA---ILTLDNVTLDDRGEYKCIGRNAA---------NVY-----GGNTTTP 585
                  .:|:|:.:|   :|.:..|.|.|.|.|.|...|.|         .||     .|::.||
 Frog  2201 ------VEDSGLVSAGGRLLQIGKVQLSDEGSYICECSNQAGSNKKEYWLEVYAQPMIAGSSNTP 2259

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
BsgNP_723346.2 IG_like 420..497 CDD:214653 19/77 (25%)
Ig 423..497 CDD:299845 17/74 (23%)
IG_like 500..583 CDD:214653 29/108 (27%)
Ig 512..575 CDD:143165 22/66 (33%)
hmcn2XP_031747766.1 vWFA 29..165 CDD:238119
IG_like 434..503 CDD:214653
Ig strand B 434..438 CDD:409353
Ig strand C 447..451 CDD:409353
Ig strand E 469..473 CDD:409353
Ig strand F 483..488 CDD:409353
Ig 514..592 CDD:416386
Ig strand A' 515..518 CDD:409353
Ig strand B 524..531 CDD:409353
Ig strand C 537..542 CDD:409353
Ig strand C' 544..546 CDD:409353
Ig strand D 551..555 CDD:409353
Ig strand E 558..563 CDD:409353
Ig strand F 571..579 CDD:409353
Ig strand G 582..592 CDD:409353
I-set 596..681 CDD:400151
Ig strand B 613..617 CDD:409353
Ig strand C 626..630 CDD:409353
Ig strand E 648..652 CDD:409353
Ig strand F 662..667 CDD:409353
Ig strand G 676..679 CDD:409353
Ig 695..770 CDD:416386
Ig strand B 703..707 CDD:409353
Ig strand C 716..720 CDD:409353
Ig strand E 736..740 CDD:409353
Ig strand F 750..755 CDD:409353
Ig strand G 763..766 CDD:409353
Ig strand A 774..778 CDD:409353
IG_like 780..864 CDD:214653
Ig strand A' 781..786 CDD:409353
Ig strand B 790..798 CDD:409353
Ig strand C 804..809 CDD:409353
Ig strand C' 812..815 CDD:409353
Ig strand D 822..825 CDD:409353
Ig strand F 843..851 CDD:409353
I-set 870..957 CDD:400151
Ig strand A' 878..881 CDD:409353
Ig strand B 887..895 CDD:409353
Ig strand C 901..906 CDD:409353
Ig strand C' 909..911 CDD:409353
Ig strand D 917..921 CDD:409353
Ig strand E 923..927 CDD:409353
Ig strand F 936..944 CDD:409353
Ig strand G 947..957 CDD:409353
I-set 961..1048 CDD:400151
Ig strand A' 969..973 CDD:409353
Ig strand B 977..984 CDD:409353
Ig strand C 991..996 CDD:409353
Ig strand C' 998..1001 CDD:409353
Ig strand D 1007..1011 CDD:409353
Ig strand E 1014..1020 CDD:409353
Ig strand F 1027..1035 CDD:409353
Ig strand G 1038..1048 CDD:409353
Ig 1065..1146 CDD:416386
Ig strand A' 1067..1070 CDD:409353
Ig strand B 1076..1083 CDD:409353
Ig strand C 1089..1094 CDD:409353
Ig strand C' 1096..1098 CDD:409353
Ig strand D 1105..1109 CDD:409353
Ig strand E 1112..1117 CDD:409353
Ig strand F 1125..1133 CDD:409353
Ig strand G 1136..1146 CDD:409353
Ig 1157..1237 CDD:416386
Ig strand B 1167..1174 CDD:409353
Ig strand C 1180..1185 CDD:409353
Ig strand C' 1187..1189 CDD:409353
Ig strand D 1196..1200 CDD:409353
Ig strand E 1203..1208 CDD:409353
Ig strand F 1216..1224 CDD:409353
Ig strand G 1227..1237 CDD:409353
Ig 1241..1329 CDD:416386
Ig strand A 1241..1244 CDD:409353
Ig strand A' 1250..1253 CDD:409353
Ig strand B 1259..1266 CDD:409353
Ig strand C 1272..1277 CDD:409353
Ig strand C' 1280..1282 CDD:409353
Ig strand D 1289..1293 CDD:409353
Ig strand E 1295..1299 CDD:409353
Ig strand F 1308..1316 CDD:409353
Ig strand G 1319..1329 CDD:409353
I-set 1342..1420 CDD:400151
Ig strand A' 1343..1346 CDD:409353
Ig strand B 1352..1359 CDD:409353
Ig strand C 1365..1370 CDD:409353
Ig strand C' 1373..1375 CDD:409353
Ig strand D 1381..1385 CDD:409353
Ig strand E 1387..1392 CDD:409353
Ig strand F 1401..1409 CDD:409353
Ig strand G 1412..1420 CDD:409353
I-set 1434..1516 CDD:400151
Ig strand A' 1436..1439 CDD:409353
Ig strand B 1445..1452 CDD:409353
Ig strand C 1458..1463 CDD:409353
Ig strand C' 1465..1467 CDD:409353
Ig strand D 1474..1478 CDD:409353
Ig strand E 1481..1487 CDD:409353
Ig strand F 1495..1503 CDD:409353
I-set 1538..1609 CDD:400151
Ig strand B 1539..1546 CDD:409353
Ig strand C 1552..1557 CDD:409353
Ig strand C' 1559..1561 CDD:409353
Ig strand D 1567..1571 CDD:409353
Ig strand E 1574..1580 CDD:409353
Ig strand F 1588..1596 CDD:409353
Ig strand G 1599..1609 CDD:409353
Ig 1621..1703 CDD:416386
Ig strand A' 1624..1628 CDD:409353
Ig strand B 1632..1639 CDD:409353
Ig strand C 1646..1651 CDD:409353
Ig strand C' 1653..1656 CDD:409353
Ig strand D 1661..1665 CDD:409353
Ig strand E 1668..1675 CDD:409353
Ig strand F 1682..1690 CDD:409353
I-set 1717..1796 CDD:400151 27/134 (20%)
Ig strand C 1739..1743 CDD:409353 1/3 (33%)
Ig strand E 1762..1766 CDD:409353 1/13 (8%)
Ig strand F 1776..1781 CDD:409353 2/4 (50%)
Ig 1796..1880 CDD:416386 14/86 (16%)
Ig strand A' 1801..1804 CDD:409353 0/2 (0%)
Ig strand B 1818..1825 CDD:409353 1/9 (11%)
Ig strand C 1831..1836 CDD:409353 0/4 (0%)
Ig strand C' 1838..1840 CDD:409353 0/1 (0%)
Ig strand F 1859..1867 CDD:409353 0/7 (0%)
Ig strand G 1870..1880 CDD:409353 3/9 (33%)
I-set 1886..1964 CDD:400151 15/81 (19%)
Ig strand A' 1892..1895 CDD:409353 2/5 (40%)
Ig strand B 1901..1908 CDD:409353 1/6 (17%)
Ig strand C 1914..1919 CDD:409353 1/4 (25%)
Ig strand C' 1920..1922 CDD:409353 0/1 (0%)
Ig strand D 1929..1933 CDD:409353 0/3 (0%)
Ig strand E 1936..1942 CDD:409353 2/5 (40%)
Ig strand F 1950..1958 CDD:409353 0/7 (0%)
Ig 1984..2063 CDD:416386 16/97 (16%)
Ig strand B 1992..1999 CDD:409353 0/6 (0%)
Ig strand C 2005..2010 CDD:409353 0/4 (0%)
Ig strand C' 2012..2014 CDD:409353 1/1 (100%)
Ig strand D 2022..2025 CDD:409353 0/2 (0%)
Ig strand E 2029..2035 CDD:409353 0/5 (0%)
Ig strand F 2042..2049 CDD:409353 2/6 (33%)
Ig strand G 2055..2063 CDD:409353 3/17 (18%)
Ig_3 2066..2141 CDD:404760 19/80 (24%)
Ig strand B 2084..2088 CDD:409353 2/3 (67%)
Ig strand C 2097..2101 CDD:409353 0/3 (0%)
Ig strand E 2120..2124 CDD:409353 0/3 (0%)
Ig strand F 2134..2139 CDD:409353 2/4 (50%)
Ig strand A 2158..2161 CDD:409353 0/2 (0%)
Ig strand A' 2167..2170 CDD:409353 0/2 (0%)
Ig 2170..2246 CDD:416386 25/84 (30%)
Ig strand B 2176..2183 CDD:409353 3/6 (50%)
Ig strand C 2189..2194 CDD:409353 3/4 (75%)
Ig strand C' 2197..2199 CDD:409353 0/1 (0%)
Ig strand E 2204..2216 CDD:409353 3/11 (27%)
Ig strand F 2225..2233 CDD:409353 3/7 (43%)
Ig strand G 2236..2246 CDD:409353 0/9 (0%)