DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33061 and Tmem38b

DIOPT Version :9

Sequence 1:	NP_001097620.1	Gene:	CG33061 / 318838	FlyBaseID:	FBgn0053061	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_001014213.1	Gene:	Tmem38b / 362521	RGDID:	1305703	Length:	291	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	69/243 - (28%)
Similarity:	110/243 - (45%)	Gaps:	21/243 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 FRILHY--SLISQQLRDELVVSAGSFRLKGGGNKVLEWQPFVLWLANLLLNYAGDILGNLLLGSL 78
            |.|.||  |:::.:.|...|.:|.|             .|...||:.:|..:.|.||..:||...
  Rat    21 FDIAHYLVSVMALKQRPGAVAAAWS-------------NPLSSWLSAMLHCFGGGILSCILLAEP 72

  Fly    79 PLEPLCNTADVMLSSLIWYCIFYCPFDLAHAVTSTLAFRILATAMSTISQVQLIDRGVHLAAQVY 143
            ||:.|.|..:::|:|.|||.:|:||.||.....|....::||..|..:::...|..||..|...|
  Rat    73 PLKFLTNHTNILLASSIWYIVFFCPRDLVSQGYSYQPIQLLAAGMKEVTRTWKIVGGVAHANGYY 137

  Fly   144 GNAPIPMLVVGTVMGSGAEVLKPVASLLINRCQHNQMAYLKLSNTSKVALFISLLFMLEVYKSPI 208
            .|..|.|:.||...|:|..::.....||....:.....:||:|...||.|..|::|..:..:.
  Rat   138 RNGWIVMIAVGWARGAGGAIITACEQLLKGDWKPEGDEWLKMSFPCKVTLLGSIMFTFQHTRH-- 200

  Fly   209 IMGINRHQLMVYILVMTTAFKFLSLCYRTDHIIWL--LEQHIRYTLFG 254
             :.|::|.||....:.....| :::....|..:.|  .|..:...|||
  Rat   201 -LAISKHDLMFLYTIFLVTIK-VTMMMTKDAAVTLTPFEDTLTRMLFG 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33061	NP_001097620.1	TRIC	45..231	CDD:282982	54/185 (29%)
Tmem38b	NP_001014213.1	TRIC	39..222	CDD:282982	57/199 (29%)
Tmem38b	NP_001014213.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	254..291
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3944
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1319985at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12454
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.880