DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33057 and TRPT1

DIOPT Version :9

Sequence 1:	NP_001286980.1	Gene:	CG33057 / 318833	FlyBaseID:	FBgn0053057	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001153861.1	Gene:	TRPT1 / 83707	HGNCID:	20316	Length:	255	Species:	Homo sapiens

Alignment Length:	214	Identity:	81/214 - (37%)
Similarity:	124/214 - (57%)	Gaps:	17/214 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QQINTQLSKKLSWLLRHGAKTEGITIRADGFVSVPDLQKHPRYLCFTLEKLKEIAAADAKQRYTL 69
            |..:.||||.||:.|||||...|:.:.|||||.:..|.:.|::..|:.|.::.:...:.|||:.|
Human    25 QDRDVQLSKALSYALRHGALKLGLPMGADGFVPLGTLLQLPQFRGFSAEDVQRVVDTNRKQRFAL 89

  Fly    70 R-WNPELGVHEIRANQGHSLAVLEGEAGGLENI------THVSQVPLAVHGTYYRHWGAIRSQGL 127
            : .:|..|: .|||||||||.|      |:..:      |..:..|:.||||:::||.:|..:||
Human    90 QLGDPSTGL-LIRANQGHSLQV------GVPKLELMPLETPQALPPMLVHGTFWKHWPSILLKGL 147

  Fly   128 SRMNRNHVHFACS-DETNSTLSGFRSDCQILIYLNVEKVLADGIPIYRSSNNVLLCPG-IEGFIH 190
            |...|.|:|.|.. ......:||.||.|:|.::::....||||||.:||:|.|:|.|| .:||:.
Human   148 SCQGRTHIHLAPGLPGDPGIISGMRSHCEIAVFIDGPLALADGIPFFRSANGVILTPGNTDGFLL 212

  Fly   191 SSYFQRVVD-KKTGQPLQI 208
            ..||:..:. :.|.:||.:
Human   213 PKYFKEALQLRPTRKPLSL 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33057	NP_001286980.1	PTS_2-RNA	11..183	CDD:280125	70/179 (39%)
TRPT1	NP_001153861.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..29		1/3 (33%)
		PTS_2-RNA	31..204	CDD:280125	70/179 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	227..255		2/5 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141424
Domainoid	1	1.000	129	1.000	Domainoid score	I5292
eggNOG	1	0.900	-	-		E1_COG1859
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12878
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4540
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54974
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005232
OrthoInspector	1	1.000	-	-		oto88613
orthoMCL	1	0.900	-	-		OOG6_102028
Panther	1	1.100	-	-	LDO	PTHR12684
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1542
SonicParanoid	1	1.000	-	-		X4245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.790