DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lz and AgaP_AGAP001094

DIOPT Version :9

Sequence 1:	NP_511099.2	Gene:	lz / 31883	FlyBaseID:	FBgn0002576	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	XP_001689117.2	Gene:	AgaP_AGAP001094 / 5666824	VectorBaseID:	AGAP001094	Length:	477	Species:	Anopheles gambiae

Alignment Length:	436	Identity:	152/436 - (34%)
Similarity:	201/436 - (46%)	Gaps:	115/436 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   281 QEHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAEVGDGTYVTIRAGNDENCCAELRNF 345
            ||:.||||:|.:|..||||||.||||||:||.||||:||.::.|||.|||:||||||..|||||.
Mosquito    32 QEYHGELVQTGSPAVLCSALPTHWRSNKSLPCAFKVIALDDIQDGTLVTIKAGNDENFHAELRNA 96

  Fly   346 TTQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVATYAKAIKVTVDGPREPRSKTSPTGG 410
            |..|||.|||||||||||||||||||::|||:::.|.|:|||.||||||||||||||||.:...|
Mosquito    97 TAVMKNQVAKFNDLRFVGRSGRGKSFSITITISSYPCQIATYTKAIKVTVDGPREPRSKQNFAYG 161

  Fly   411 ------PHYRALGLGQRPYI-----DGF-----------PSTKALHELESLRRSAKVAAVTTAAA 453
                  |.....|.....|:     |.|           |.:.|:.. .::.....:::.||||.
Mosquito   162 HPGPFNPFILNAGWLDAAYMNYAWSDYFRQHQQQQVMQVPPSSAVSN-GTISNGHVISSTTTAAG 225

  Fly   454 AAATA-------ASAANAVAAAAAAVAVTPTGGGGGVAAGGVAGGAGAGLVQQLSSN--YSSPNS 509
            .|..|       .|::.:|.|...|..:.|...|                   |.|.  .:||.|
Mosquito   226 IAEPAKDIVPVRTSSSQSVPAPTMAPGINPPSKG-------------------LPSPALLASPTS 271

  Fly   510 T----------INSDCQVYKPNAPHI-----------QAAEMMGAGEWTNG------SSSSAAAY 547
            |          |:||.|:.||  |.:           .||....|...|||      .|::.|.:
Mosquito   272 TYPPRAISSLEIHSDPQLVKP--PFLPYDIAAFRSTAAAAAAAAAAAATNGILRPAELSTTIALH 334

  Fly   548 YHSHAHHPHAHHAHAHLQHQMALPPPPPPPAAAPVSVGVGGNGATMGMGMGVGVGMGMNHYGGGY 612
            ..::.....:..:.|..::....|||       .:|..:|.:.:                 .|..
Mosquito   335 QSTNIDSASSRLSPASSRNSNNSPPP-------VLSSSIGNDTS-----------------NGDL 375

  Fly   613 DSANSLEAGQ------YAAHLPAVLP--EMHGHGFATDPYQTAGYG 650
            .|||..|:..      .:|.:|.:.|  .:.....|..|   |.||
Mosquito   376 SSANEDESDDEQIDVVKSAFIPILRPPAALSSETTANSP---ARYG 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lz	NP_511099.2	Runt	283..404	CDD:279225	88/120 (73%)
AgaP_AGAP001094	XP_001689117.2	Runt	34..155	CDD:279225	88/120 (73%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3982
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D109070at6656
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X738
TreeFam	0	0.000	Not matched by this tool.
	6	5.920