Protein Alignment lz and runx2b

DIOPT Version :9

• Sequence 1: NP_511099.2
• Gene: lz / 31883
• FlyBaseID: FBgn0002576
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_998027.2
• Gene: runx2b / 405788
• ZFINID: ZDB-GENE-040629-4
• Length: 464
• Species: Danio rerio
• Alignment Length: 610
• Identity: 184/610 - (30%)
• Similarity: 228/610 - (37%)
• Gaps: 225/610 - (36%)

  Fly   258 NSNNNNAVHQDLLWMERLVQKRQQE----------HPGELVRTSNPYFLCSALPAHWRSNKTLPM 312
            |||......||...:.||   |.||          ||.|||||.:|.||||.||:|||.|||||:
Zfish    39 NSNAGPQQQQDGAVVPRL---RAQENRSMAEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPV 100

  Fly   313 AFKVVALAEVGDGTYVTIRAGNDENCCAELRNFTTQMKNDVAKFNDLRFVGRSGRGKSFTLTITV 377
            |||||||.||.|||.||:.||||||..|||||.:..|||.||:||||||||||||||||||||||
Zfish   101 AFKVVALGEVPDGTVVTVMAGNDENYSAELRNASGVMKNQVARFNDLRFVGRSGRGKSFTLTITV 165

  Fly   378 ATSPPQVATYAKAIKVTVDGPREPRSKTSPTGGPHYRALGLGQRPYIDGFPS----TKALHELES 438
            .|:|||||||.:|||||||||||||.                .||.:|..|.    :..|.|||.
Zfish   166 FTNPPQVATYHRAIKVTVDGPREPRR----------------HRPKLDDSPKAGLFSDRLSELER 214

  Fly   439 LRRSAKVAAVTTAAAAAATAASAANAVAAAAAAVAVTPTGGGGGVAAGGVAGGAGAGLVQQLSSN 503
            :|::.....|.|.                       ||                        ..:
Zfish   215 IRQTTMRVTVPTQ-----------------------TP------------------------RPS 232

  Fly   504 YSSPNS-TINSDCQVYKPNAPHIQAAEMMGAGEWTNGSSSSAAAYYHSHAHHPHAHHAHAHLQHQ 567
            .||||| |.....|:..|.       :...:..|   |.......|.|....|.. |:...|...
Zfish   233 LSSPNSYTPQGQTQITDPR-------QAQSSPPW---SYDQTYPSYLSPMASPSV-HSTTPLSSS 286

  Fly   568 MA--LPPPPPPPAAAPVSVGVGGNGATMGMGMGVGVGMGMNHYGGGYD----SANSLEAGQYAA- 625
            .|  ||.....|...|        |:|           .::.:.|.::    :.:||...::::
Zfish   287 RATGLPSISDVPRRLP--------GST-----------DLSPFPGQFERQFPAFSSLTESRFSSP 332

  Fly   626 --HLPAV-------------LPEMHGHGFATDPYQTAGYGGGNTGGG---SASKSELDYGGSYNQ 672
              |.||.             |...|.|.:...||.    |...:..|   |:|...|.||.|
Zfish   333 RMHYPATFTYTPTPVTTGMSLGSAHYHTYLPPPYP----GSTQSQSGPFQSSSTPYLYYGAS--- 390

  Fly   673 AWSNGYQNYQYGSCLATAQYGPQAAPPPQPPPPPPVVLCPQLYSTVNQNQIHLHLHSSEKLEQYL 737
              |..||        .:...|.:.:|....||
Zfish   391 --SGSYQ--------FSMVPGGERSPTRMMPP--------------------------------- 412

  Fly   738 GTATSADHLTIGSLTGSSRSSIEIGQDQYHQQVHHAQQQQQQQQQQQQVHHPQQQQVESAGEVGG 802
              .|||.       ||:|                             .|:.....|.:.:|.|.|
Zfish   413 --CTSAS-------TGTS-----------------------------LVNPNLPVQADGSGGVEG 439

  Fly   803 SGAGGVESAREEDVGDLSQ-VWRPY 826
            .|:...........|.:.: |||||
Zfish   440 DGSHSNSPTLLNPAGRMDEGVWRPY 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lz	NP_511099.2	Runt	283..404	CDD:279225	95/120 (79%)
runx2b	NP_998027.2	Runt	71..192	CDD:279225	95/136 (70%)
		RunxI	370..464	CDD:285676	30/177 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.010