Protein Alignment lz and runx2a

DIOPT Version :9

• Sequence 1: NP_511099.2
• Gene: lz / 31883
• FlyBaseID: FBgn0002576
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_998023.1
• Gene: runx2a / 405784
• ZFINID: ZDB-GENE-040629-3
• Length: 467
• Species: Danio rerio
• Alignment Length: 416
• Identity: 147/416 - (35%)
• Similarity: 188/416 - (45%)
• Gaps: 102/416 - (24%)

  Fly   282 EHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAEVGDGTYVTIRAGNDENCCAELRNFT 346
            :||.|||||.:|.||||.||:|||.|||||:|||||||.:|.|||.||:.||||||..|||||.:
Zfish    69 DHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNAS 133

  Fly   347 TQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVATYAKAIKVTVDGPREPRSKTSPTGGP 411
            ..|||.||:||||||||||||||||||||||.|:|||||||.:|||||||||||||.
Zfish   134 AVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR-------- 190

  Fly   412 HYRALGLGQRPYIDGFPSTKALHELESLRRSAKVAAVTTAAAAAATAASAANAVAAAAAAVAVTP 476
            |.:.|....:|.:    .::.|.|||.||::....||.|.:...:..|:..          :..|
Zfish   191 HRQKLEDPPKPPL----FSERLSELERLRQTTMRVAVQTQSPRPSLNATPN----------SFNP 241

  Fly   477 TGGGGGVAAGGVAGGAGAGLVQQLSSNYSSPNSTINSDCQVYKP-----NAPHIQAAEMMGAGEW 536
            .|                  ..|:|....:.:|...|..|.|.|     .:|.|.:
Zfish   242 QG------------------QTQISDPRQAQSSPPWSYEQPYPPYLSQMTSPSIHS--------- 279

  Fly   537 TNGSSSSAAAYYHSHAHHPHAHHAHAHLQHQMALPPP----------------PPPPAAAPVSVG 585
            |...||:.|....:.:..|......:.|....|.|..                |.|....|.:..
Zfish   280 TTPLSSTRATGLPTISDVPRRLSGTSELSPFSADPRQFERQFPSLSSLTDSRFPSPRMHYPATFT 344

  Fly   586 VGGNGATMGMGMGVGVGMGMNHYGGGYDSANSLEAGQYAAHLPAVLPEMHGHGFATDPYQTAG-- 648
            ......|.||.:|:..                  ...|..:||...|....:  .:.|:||:.
Zfish   345 YTPTPVTSGMSLGMST------------------TTHYHTYLPPPYPGSTQN--QSGPFQTSSTP 389

  Fly   649 --YGGGNTG--------GGSASKSEL 664
              |.|.::|        ||..|.|.:
Zfish   390 YLYYGASSGSYQFPMVPGGDRSPSRM 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lz	NP_511099.2	Runt	283..404	CDD:279225	94/120 (78%)
runx2a	NP_998023.1	Runt	70..191	CDD:279225	94/128 (73%)
		RunxI	376..467	CDD:285676	10/42 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3982
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.870