Protein Alignment lz and Runx2

DIOPT Version :9

• Sequence 1: NP_511099.2
• Gene: lz / 31883
• FlyBaseID: FBgn0002576
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: XP_038939882.1
• Gene: Runx2 / 367218
• RGDID: 2282
• Length: 652
• Species: Rattus norvegicus
• Alignment Length: 414
• Identity: 144/414 - (34%)
• Similarity: 183/414 - (44%)
• Gaps: 130/414 - (31%)

  Fly   282 EHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAEVGDGTYVTIRAGNDENCCAELRNFT 346
            :||.|||||.:|.||||.||:|||.|||||:|||||||.||.|||.||:.||||||..|||||.:
  Rat   220 DHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNAS 284

  Fly   347 TQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVATYAKAIKVTVDGPREPR--------- 402
            ..|||.||:||||||||||||||||||||||.|:|||||||.:|||||||||||||
  Rat   285 AVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDS 349

  Fly   403 ------SKTSPTGGPHYRALGLGQRP-----------------------------------YIDG 426
                  .:.|..|...:.::.:|..|                                   |...
  Rat   350 KPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQTQSSPPWSYDQS 414

  Fly   427 FPS------TKALHE---LESLR------------------------RSAKVAAVTTAAAAAATA 458
            :||      :.::|.   |.|.|                        :|:....:::.....:||
  Rat   415 YPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDSEPSTLDSQSSTTLFLSSEEPGPSTA 479

  Fly   459 ASAANAVAAAAAAVAVTPTGGGGGVAAGGVAGGAGAGLVQQLSSNY----SSPNSTINSDCQVYK 519
            |..:.:.:......:.:||.....:....:|..|.|..|.:.:..|    |||.:
  Rat   480 ALPSPSSSCEPQPFSPSPTMLPSLLQPLPIASTAPAPCVPRRTGLYTIVTSSPEA---------- 534

  Fly   520 PNAPHIQAAEMMGAGEWTNGSSSS-------------------AAAYYHSHAHHP-HAHHAHAHL 564
              |||:.        :|.....|:                   |.|....|..|| .|...||
  Rat   535 --APHLV--------DWLPSCPSATSPGVRGKDRERPQTMLAPAPALERGHNQHPGPARDGHA-- 587

  Fly   565 QHQMALPPPPPPPAAAP-VSVGVG 587
            :|....|||..|||.|| :...||
  Rat   588 EHAGTSPPPCSPPATAPTLEANVG 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lz	NP_511099.2	Runt	283..404	CDD:279225	95/135 (70%)
Runx2	XP_038939882.1	Runt	217..343	CDD:395684	95/122 (78%)
		PHA03247	<319..606	CDD:223021	67/308 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3982
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.770