Protein Alignment lz and AgaP_AGAP002506

DIOPT Version :9

• Sequence 1: NP_511099.2
• Gene: lz / 31883
• FlyBaseID: FBgn0002576
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: XP_312433.5
• Gene: AgaP_AGAP002506 / 1273456
• VectorBaseID: AGAP002506
• Length: 674
• Species: Anopheles gambiae
• Alignment Length: 757
• Identity: 267/757 - (35%)
• Similarity: 326/757 - (43%)
• Gaps: 239/757 - (31%)

  Fly   197 TASTGATAAEVLAVSSSASVGSSSPTGGASNGTAHSGHSGHTGGHSSSTASNNNNNGASNSNSNN 261
            ||.||             .:.:.:.|.|...||...|...::||......|.||    ..|::.:
Mosquito    30 TAGTG-------------MLETGTATSGGDAGTQPGGSCRNSGGTGVLQPSQNN----GGSHATD 77

  Fly   262 NNAVHQDLLWMERLVQKRQQEHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAEVGDGT 326
            :||:..||.||||:|.:.:|::|||||||.:|||||||||.|||||||||.||||::|.:|.|||
Mosquito    78 DNAIPADLRWMERMVMEAEQQYPGELVRTDSPYFLCSALPNHWRSNKTLPSAFKVISLGDVSDGT 142

  Fly   327 YVTIRAGNDENCCAELRNFTTQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVATYAKAI 391
            .||||||||||.||||||.|..|:|.||||||||||||||||||||||||:.|:.|||.||.|||
Mosquito   143 MVTIRAGNDENFCAELRNCTAVMRNQVAKFNDLRFVGRSGRGKSFTLTITICTTMPQVTTYCKAI 207

  Fly   392 KVTVDGPREPRSKTSP------------------TGGPHYRALGLGQRPYIDGFPSTKALHELES 438
            |||||||||||||||.                  .||..|  :...:.|.:..|....|.:....
Mosquito   208 KVTVDGPREPRSKTSKLNCIRSSWSRRVLVWGCVNGGTTY--MPQMRPPPLHRFLEQPAFNHHHY 270

  Fly   439 LRRSAKVAAVTTAAAAAATAASAAN----------AVAAAAAAVAVTPTGGGGGVAAGGVAGGAG 493
            ..|.....    ....:.|.:|::|          .:.:.......|.:.||||.|..|...|.|
Mosquito   271 PGRPGSFG----GTGGSNTGSSSSNNNNNNNNNGGGLGSNGLGTGSTGSLGGGGTAGTGHGNGNG 331

  Fly   494 AGLVQQLSSNYSSPNSTINSDCQVYKPNAPHIQAAEMMGAGEWTNGSSSSAAAYYHSHAHHPHAH 558
                :..|.|||:.:||                       |..||           .|.||||.|
Mosquito   332 ----KSSSVNYSAVSST-----------------------GSTTN-----------LHTHHPHHH 358

  Fly   559 HAHAHLQHQMALPPPPPPPAAAPVSVGVGGNGATMGMGMGVGVGMGMN-------HYGGGYDSAN 616
            |.|.|  |                  |.||.|     |.|.|..|.:|       .|.......:
Mosquito   359 HHHHH--H------------------GSGGGG-----GGGGGGNMAINTSAESSSDYKPNLAFTD 398

  Fly   617 SLEAGQ--Y----------AAHLPAVLPEMHGHGFATDPYQTAGYGGGNTGGGSA--SKS-ELDY 666
            :|:..|  |          |..:.||.|..     .|...||...||....|||:  ||: ||..
Mosquito   399 NLQPYQDYYGLSGPPPPPPAPTVAAVAPPT-----GTSTVQTGPLGGQLAAGGSSYVSKTGELVE 458

  Fly   667 GGS---------YNQAWSNGY-------QNYQY-----------GSC---LATAQYGP------- 694
            ..:         ::..|:|||       .::||           |.|   ||.|...|
Mosquito   459 AAATTTTYPSYPHHTQWTNGYHGSYHHHHHHQYNHPAAAAAASAGGCASSLAVAAQSPVSFHPPV 523

  Fly   695 --QAAPPPQ----PPPPPPVVLCPQLYSTVNQNQIHLHLH--SSEKLEQYLGTATSADHLTIGSL 751
              .|||.|.    ||||||:|||||::|||||||||:|||  .|:|.|.|.|:|.:.  .||.|.
Mosquito   524 ATVAAPAPSSVPAPPPPPPMVLCPQMFSTVNQNQIHVHLHGTGSDKFEHYFGSADNG--FTINSF 586

  Fly   752 TGSSRSSIEIGQ------------------DQYHQ--------------QVHHAQQQQQQQQQQQ 784
            .|.|..|:..|.                  ..:||              ..||...|.....:|
Mosquito   587 PGPSIRSVASGPIASTLHAGTAVDIGGIAGAHHHQDSGGGANDTLTALLSAHHDDPQHSGGSEQ- 650

  Fly   785 QVHHPQQQQVESAGEVGGSGAGGVESAREEDVGDLSQVWRPY 826
                 ||||.|..||             |...||.|.|||||
Mosquito   651 -----QQQQDEGRGE-------------ESVSGDPSSVWRPY 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lz	NP_511099.2	Runt	283..404	CDD:279225	97/120 (81%)
AgaP_AGAP002506	XP_312433.5	Runt	99..220	CDD:279225	97/120 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3982
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	316	1.000	Inparanoid score	I4894
OMA	1	1.010	-	-		QHG26716
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	1	1.000	-	-		oto106530
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
TreeFam	1	0.960	-	-
	8	7.920