DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpy and DPB

DIOPT Version :9

Sequence 1:	NP_001260032.1	Gene:	dpy / 318824	FlyBaseID:	FBgn0053196	Length:	22949	Species:	Drosophila melanogaster
Sequence 2:	NP_850757.1	Gene:	DPB / 831847	AraportID:	AT5G03415	Length:	385	Species:	Arabidopsis thaliana

Alignment Length:	445	Identity:	88/445 - (19%)
Similarity:	147/445 - (33%)	Gaps:	139/445 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  6760 HSDQTTESTRDVPTTRPF-------------EASTPSPASLET-TVPSVTSETT----TNVPI-- 6804
            |:...:.:..:.|:||.:             ...:||..|.:| ||.:.||:||    .|:.|
plant    10 HNHHESNNNNNNPSTRSWGTAVSGQSVSTSGSMGSPSSRSEQTITVVTSTSDTTFQRLNNLDIQG 74

  Fly  6805 ---GSTGGQVTE-----QTTSSP-------------------SEVRTTIG------LEESTLPSR 6836
               ||.|....:     |..:.|                   |:.|||..      :.|..||
plant    75 DDAGSQGASGVKKKKRGQRAAGPDKTGRGLRQFSMKVCEKVESKGRTTYNEVADELVAEFALP-- 137

  Fly  6837 STDRTSPSES------------PETPTTLPSDFITRPHSDQTTESTRDVPTTRPFEASTPSPASL 6889
            :.|.|||.:.            ......:..|.|::   |:.....|.:|.|           ||
plant   138 NNDGTSPDQQQYDEKNIRRRVYDALNVLMAMDIISK---DKKEIQWRGLPRT-----------SL 188

  Fly  6890 ETTVPSVTSETTTNVPIGSTGGQVTEQTTSSPSEVRTTIGLEESTLPSRSTDRTSPSESPETPTT 6954
             :.:..:.:|..      |...::.::|..|.......:||:  .|..|:....|...:|.....
plant   189 -SDIEELKNERL------SLRNRIEKKTAYSQELEEQYVGLQ--NLIQRNEHLYSSGNAPSGGVA 244

  Fly  6955 LPSDFI---TRPHSDQTTESTRDVPTTRPFEASTPSSASLETTVPSVTLETTTNVPIGSTGGQVT 7016
            ||  ||   ||||:....|.:.|:........|||    .|....:..|:|.          :..
plant   245 LP--FILVQTRPHATVEVEISEDMQLVHFDFNSTP----FELHDDNFVLKTM----------KFC 293

  Fly  7017 EQTTSSPSEVRTTIRVEESTLPSRSTDRTTPSESPET-PTTLPSDFTTRPHSDQTTESSRDVPTT 7080
            :|....|:....:..|..:..|.      .|::.|.| ||.....:.|...|.|..:.|:
plant   294 DQPPQQPNGRNNSQLVCHNFTPE------NPNKGPSTGPTPQLDMYETHLQSQQHQQHSQ----- 347

  Fly  7081 QPFEASTPRPVTLQTAVLPVTSETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVE 7135
                        ||...:|.|:..|      |:......::.|.|..:.::::.|
plant   348 ------------LQIIPMPETNNVT------SSADTAPVKSPSLPGIMNSSMKPE 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpy	NP_001260032.1	EGF_3	137..166	CDD:289699
		EGF_CA	212..247	CDD:238011
		EGF_CA	255..>286	CDD:214542
		EGF_CA	298..331	CDD:238011
		EGF_CA	338..373	CDD:238011
		EGF_CA	413..456	CDD:238011
		EGF_CA	457..490	CDD:238011
		EGF_CA	497..>529	CDD:214542
		EGF_CA	580..>612	CDD:214542
		EGF_3	676..702	CDD:289699
		EGF_CA	1022..1056	CDD:214542
		EGF_CA	2227..2260	CDD:238011
		EGF_CA	2393..>2422	CDD:214542
		DUF4758	4088..4282	CDD:292572
		DUF4696	4127..4678	CDD:292395
		DUF4758	4275..4448	CDD:292572
		DUF4758	4377..4574	CDD:292572
		DUF4758	4581..4754	CDD:292572
		DUF4758	4683..4847	CDD:292572
		DUF4758	4785..4964	CDD:292572
		DUF4696	4841..5385	CDD:292395
		DUF4758	4887..5098	CDD:292572
		DUF4758	5193..5371	CDD:292572
		DUF4758	5294..5487	CDD:292572
		DUF4758	5445..5650	CDD:292572
		DUF4758	5700..5877	CDD:292572
		DUF4696	5756..6396	CDD:292395
		DUF4758	5802..5979	CDD:292572
		DUF4758	5964..6171	CDD:292572
		DUF4758	6181..6360	CDD:292572
		DUF4696	6339..6999	CDD:292395	64/306 (21%)
		DUF4758	6662..6839	CDD:292572	28/131 (21%)
		DUF4758	6764..6941	CDD:292572	47/241 (20%)
		DUF4758	6866..7045	CDD:292572	35/181 (19%)
		DUF4758	6968..7179	CDD:292572	30/169 (18%)
		DUF4696	7024..7569	CDD:292395	20/113 (18%)
		DUF4758	7172..7383	CDD:292572
		DUF4696	7330..7964	CDD:292395
		DUF4758	7400..7587	CDD:292572
		DUF4758	7538..7707	CDD:292572
		DUF4758	7798..7979	CDD:292572
		DUF4758	7946..8126	CDD:292572
		YppG	18767..>18832	CDD:290883
		Med25_SD1	18795..18955	CDD:288132
		MISS	19026..19258	CDD:292450
		ZP	22576..22811	CDD:214579
		Zona_pellucida	<22714..22810	CDD:278526
DPB	NP_850757.1	E2F_TDP	101..182	CDD:280479	14/85 (16%)
		coiled coil	187..233	CDD:271217	10/54 (19%)
		DP	189..>295	CDD:285934	26/129 (20%)
		Neural_ProG_Cyt	276..>320	CDD:284080	10/63 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000