DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpy and Vim

DIOPT Version :9

Sequence 1:NP_001260032.1 Gene:dpy / 318824 FlyBaseID:FBgn0053196 Length:22949 Species:Drosophila melanogaster
Sequence 2:NP_112402.1 Gene:Vim / 81818 RGDID:621646 Length:466 Species:Rattus norvegicus


Alignment Length:381 Identity:73/381 - (19%)
Similarity:120/381 - (31%) Gaps:125/381 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly  7737 GSTGGQVAGQTTAPPSEVRTTIRVEESTLPSRSADRTTPSESPETPTTLPSDFTTRPHSEQTTES 7801
            |.:|      |::.||..|:.:.....|....||.|         |:|..|.:::.|.....|.|
  Rat    16 GGSG------TSSRPSSNRSYVTTSTRTYSLGSALR---------PSTSRSLYSSSPGGAYVTRS 65

  Fly  7802 T-----RDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPI----------------------- 7838
            :     ..:|..|..:.|.  ..||...:.:....|.||..:                       
  Rat    66 SAVRLRSSMPGVRLLQDSV--DFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQN 128

  Fly  7839 -----------GSTGGQLTEQSTSSPSEVRTTI--------RVEESTLPSRSTDRTFPSES---- 7880
                       |....:|.:.......|:|..:        |||        .:|...:|.    
  Rat   129 KILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVE--------VERDNLAEDIMRL 185

  Fly  7881 PEKPTTLPSDFTTRPHLEQTTESTR-DVLTTRPFETSTPSPVSLETTVPSVTSETS-----TNVP 7939
            .||   |..:...|...|.|.:|.| ||      :.::.:.:.||..|.|:..|.:     .:..
  Rat   186 REK---LQEEMLQREEAESTLQSFRQDV------DNASLARLDLERKVESLQEEIAFLKKLHDEE 241

  Fly  7940 IGSTGGQVTEQTTAPPSVRTTETIVKSTHPAVSPDTTIPSEIPATR-----------VPLESTTR 7993
            |.....|:.||                 |..:..|.:.|....|.|           ..|:....
  Rat   242 IQELQAQIQEQ-----------------HVQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEE 289

  Fly  7994 LYTDQTIPPGSTDRTTSSERPDESTRLTSEESTETTRPVPTVSPR-DALETTVTSL 8048
            .|..:     ..|.:.::.|.:::.|...:||.|..|.|.:::.. |||:.|..||
  Rat   290 WYKSK-----FADLSEAANRNNDALRQAKQESNEYRRQVQSLTCEVDALKGTNESL 340

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpyNP_001260032.1 EGF_3 137..166 CDD:289699
EGF_CA 212..247 CDD:238011
EGF_CA 255..>286 CDD:214542
EGF_CA 298..331 CDD:238011
EGF_CA 338..373 CDD:238011
EGF_CA 413..456 CDD:238011
EGF_CA 457..490 CDD:238011
EGF_CA 497..>529 CDD:214542
EGF_CA 580..>612 CDD:214542
EGF_3 676..702 CDD:289699
EGF_CA 1022..1056 CDD:214542
EGF_CA 2227..2260 CDD:238011
EGF_CA 2393..>2422 CDD:214542
DUF4758 4088..4282 CDD:292572
DUF4696 4127..4678 CDD:292395
DUF4758 4275..4448 CDD:292572
DUF4758 4377..4574 CDD:292572
DUF4758 4581..4754 CDD:292572
DUF4758 4683..4847 CDD:292572
DUF4758 4785..4964 CDD:292572
DUF4696 4841..5385 CDD:292395
DUF4758 4887..5098 CDD:292572
DUF4758 5193..5371 CDD:292572
DUF4758 5294..5487 CDD:292572
DUF4758 5445..5650 CDD:292572
DUF4758 5700..5877 CDD:292572
DUF4696 5756..6396 CDD:292395
DUF4758 5802..5979 CDD:292572
DUF4758 5964..6171 CDD:292572
DUF4758 6181..6360 CDD:292572
DUF4696 6339..6999 CDD:292395
DUF4758 6662..6839 CDD:292572
DUF4758 6764..6941 CDD:292572
DUF4758 6866..7045 CDD:292572
DUF4758 6968..7179 CDD:292572
DUF4696 7024..7569 CDD:292395
DUF4758 7172..7383 CDD:292572
DUF4696 7330..7964 CDD:292395 52/283 (18%)
DUF4758 7400..7587 CDD:292572
DUF4758 7538..7707 CDD:292572
DUF4758 7798..7979 CDD:292572 40/237 (17%)
DUF4758 7946..8126 CDD:292572 24/115 (21%)
YppG 18767..>18832 CDD:290883
Med25_SD1 18795..18955 CDD:288132
MISS 19026..19258 CDD:292450
ZP 22576..22811 CDD:214579
Zona_pellucida <22714..22810 CDD:278526
VimNP_112402.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..33 6/22 (27%)
Head 2..95 21/95 (22%)
Filament_head 14..101 CDD:282575 22/101 (22%)
Coil 1A 96..131 3/34 (9%)
Filament 102..410 CDD:278467 50/278 (18%)
Linker 1 132..153 2/20 (10%)
DUF4559 <153..257 CDD:291771 27/137 (20%)
Coil 1B 154..245 23/107 (21%)
Linker 12 246..268 6/38 (16%)
Coil 2 269..407 17/77 (22%)
[IL]-x-C-x-x-[DE] motif. /evidence=ECO:0000250|UniProtKB:P08670 326..329 0/2 (0%)
Tail 408..466
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.