Protein Alignment dpy and TNXB

DIOPT Version :9

• Sequence 1: NP_001260032.1
• Gene: dpy / 318824
• FlyBaseID: FBgn0053196
• Length: 22949
• Species: Drosophila melanogaster
• Sequence 2: NP_001352205.1
• Gene: TNXB / 7148
• HGNCID: 11976
• Length: 4244
• Species: Homo sapiens
• Alignment Length: 5211
• Identity: 996/5211 - (19%)
• Similarity: 1399/5211 - (26%)
• Gaps: 2251/5211 - (43%)

  Fly  2410 NLPGSYSCQCPEG----LIGDPLQA-------------GCRDPNECLSDADCPASASCQNSR--C 2455
            |||.|..|.||.|    ::...:||             |.::  :|.... |||||.....:  .
Human    78 NLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKE--QCTGGC-CPASAQAGTGQTDV 139

  Fly  2456 RSPCERQNACGLNANCQAQAHQAICTCPLN-SRGDPTIECVHIECADNDDCSGEKACLDSKCIDP 2519
            |:.|.......|:.          |||... ..|.||       |:|..|..          |.|
Human   140 RTLCSLHGVFDLSR----------CTCSCEPGWGGPT-------CSDPTDAE----------IPP 177

  Fly  2520 CSLPNACGALARCSVQNHIGVCSCEAGSTGDAKLGCVQLQYCQQDGQCAQG-SICSHGICSPLC- 2582
            .|.|:|.|              ||.              ..|...|:|.:| .:|..|...|.|
Human   178 SSPPSASG--------------SCP--------------DDCNDQGRCVRGRCVCFPGYTGPSCG 214

  Fly  2583 --STNRDCISEQLCLQGVCQGTCKSNSSCPQFQFCSNNICTKELECRSDSECGEDETCLSDAYGR 2645
              |...||.....|:||||  .|::..|.|.   ||...|.:        .|.:          |
Human   215 WPSCPGDCQGRGRCVQGVC--VCRAGFSGPD---CSQRSCPR--------GCSQ----------R 256

  Fly  2646 AKCESVCLGRAACGRNAECVARSHAPDCLCKEGFFGDAKSGCRKIECTSDDDCSNDKSCDNHMCK 2710
            .:||.        ||            |:|..|:.|              |||.. :||.
Human   257 GRCEG--------GR------------CVCDPGYTG--------------DDCGM-RSCP----- 281

  Fly  2711 IACLIGQPCGENALCTTEHHQQVCHCQPGFSGDPRVRCDVIDFCRDAP--CGPGARCRNARGSYK 2773
                  :.|.:...|....    |.|.||::|:.   |.|    |..|  |....||::.|
Human   282 ------RGCSQRGRCENGR----CVCNPGYTGED---CGV----RSCPRGCSQRGRCKDGR---- 325

  Fly  2774 CTCPPGLVGDPYNEGCRSSVECETNEDCPPHAACTKTNGVAKCRDVCAQLQCGPNAECVPKGHVA 2838
            |.|.||..|                |||          |...|     ...||....||.    .
Human   326 CVCDPGYTG----------------EDC----------GTRSC-----PWDCGEGGRCVD----G 355

  Fly  2839 QCACRSGYDGQPADRVAGCKPLPSPCQVTGDCPTNTYCSDSVCKPACVLDTECGAFEVCQG-GQC 2902
            :|.|..||.|:                   ||.|.|          |..|        |:| |:|
Human   356 RCVCWPGYTGE-------------------DCSTRT----------CPRD--------CRGRGRC 383

  Fly  2903 FNPCLQPQACGQNAECVMQNHLKQCHCPEGFTGDSAKEC-VRVPVACDGECGPGYTCRDSMCLPV 2966
                       ::.||:         |..|::||   :| ||   :|.|:|.....|.|..|:
Human   384 -----------EDGECI---------CDTGYSGD---DCGVR---SCPGDCNQRGRCEDGRCV-- 420

  Fly  2967 CHNDLECASNEKCLKGSCMLTCRVDNDCFLGHVCLHNKCVYGCHVDDDCSASESCRNDKCVNPCL 3031
                        |..|            :.|..|....|      ..||.....|.|..||
Human   421 ------------CWPG------------YTGTDCGSRAC------PRDCRGRGRCENGVCV---- 451

  Fly  3032 ENPCGPNAACSVSNHRASCSCLESMVPNPTPQVGCVRSPPLECRENRDCGNGLACFESVCRPLCA 3096
                     |:.......|.               |||.|.:||     |.|
Human   452 ---------CNAGYSGEDCG---------------VRSCPGDCR-----GRG------------- 474

  Fly  3097 DDAGCLTNERCQQGVCKPLCRHDNECGHGELCLGLNCVPGCRSDQGCPPELSCVGQQCVDPCADP 3161
                     ||:.|.|.                   |.||            ..|:.
Human   475 ---------RCESGRCM-------------------CWPG------------YTGRD-------- 491

  Fly  3162 TACGTNAHCQTIDHRKQCLCPEGLDGNANVACKVPRIACGRNEDCQSNQLCYAGSCQGKCRNDQN 3226
              |||.|            ||                                |.|:|:
Human   492 --CGTRA------------CP--------------------------------GDCRGR------ 504

  Fly  3227 CLADERCMRGTCRTVCNTDEACAQGQICENRMCQTGCRTDLSCATDEACVNKKCQNPCRTPGQCG 3291
                .||:.|.|  |||..                        .|.|.|.:::|...||..|.|
Human   505 ----GRCVDGRC--VCNPG------------------------FTGEDCGSRRCPGDCRGHGLC- 538

  Fly  3292 QCADCLVVNHGVQCQCPAAFMGDGLTGCQLPPERCHPDCECDENGAYCAPKCSRTEDCACG---- 3352
                    ..|| |.|.|.:.|:              ||.              |..|..|
Human   539 --------EDGV-CVCDAGYSGE--------------DCS--------------TRSCPGGCRGR 566

  Fly  3353 QQCARGKCRNKCGPKRQCTVGQLCERGACIAGCKSNGDCAADQSCVNGKCSDPCANEKACGRNAL 3417
            .||..|:|              :||.|      .|..||...|          |.|:  |.::.:
Human   567 GQCLDGRC--------------VCEDG------YSGEDCGVRQ----------CPND--CSQHGV 599

  Fly  3418 CTVSEHRMLCYCPDGYEGEPSKECVQFECRVDT---DCDSNKRCDQGKCR-NPCLEYGACGTN-- 3476
            |...    :|.|.:||..|        :|.:.|   :|....||::|:|. :|......|.|.
Human   600 CQDG----VCICWEGYVSE--------DCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMC 652

  Fly  3477 -AQCRVVGRKAQ--CSCPPDFFGNPTSECRPLEGGCSSKPCGENSKCTEVPGGYECACMDGCIGD 3538
             |.||..||..|  |.|               ..|...:.||:.    |.|..   ||..||
Human   653 PADCRGRGRCVQGVCLC---------------HVGYGGEDCGQE----EPPAS---ACPGGC--- 692

  Fly  3539 AHQGCLCGGPLVNACRDQPCGLNAACHVLENNQAECYCPEDFPNGDAYVQCYLTTPKQDCRTLG- 3602
                    ||. ..||                ..:|.|.|.|...|    |.:.|...|||..|
Human   693 --------GPR-ELCR----------------AGQCVCVEGFRGPD----CAIQTCPGDCRGRGE 728

  Fly  3603 CEVGGCVRQGYEYVCQQDTEQCYSDTDCPSEKSCLQGHCSDPCTMRGVCGLNALCKTVLHRPRCS 3667
            |..|.|       ||:..    |:..||..|...::|       ||    ::.|.:|.:......
Human   729 CHDGSC-------VCKDG----YAGEDCGEEVPTIEG-------MR----MHLLEETTVRTEWTP 771

  Fly  3668 CPSCHIGRPEIECKSDPKCVAEDTDPKTKEQIPCSTDSECPETLQCGQYGQCTDPCNNPLFICES 3732
            .|. .:...||:...    ..|...|....::|.|..:.....|..||..|.|
Human   772 APG-PVDAYEIQFIP----TTEGASPPFTARVPSSASAYDQRGLAPGQEYQVT------------ 819

  Fly  3733 NKKCETRRHQPVCICKSGFIVNEYGELTCAPDKRECYRDDDCASNMACSDGKCRNPCIVPLGRAA 3797
                                                                             
Human   820 ----------------------------------------------------------------- 819

  Fly  3798 ICAENKSCEVQNHKPVCICMRDCQPSISICLRDA--GCPASQACRKLKCVDPCEFATCAPNSPCI 3860
                               :|        .||..  |.|||:....:  :|..:.......:|..
Human   820 -------------------VR--------ALRGTSWGLPASKTITTM--IDGPQDLRVVAVTPTT 855

  Fly  3861 VE-----DHKPICKFCPAGFIADAKNGCQKAK----PGGNCTSNTDCSQAHQCGSSGKCIDPCLT 3916
            :|     ....:.:|    .::....|.|:.:    |..:.|                    .||
Human   856 LELGWLRPQAEVDRF----VVSYVSAGNQRVRLEVPPEADGT--------------------LLT 896

  Fly  3917 SCAGGVKCV--VSAHRVTICTCPATLTNNTDSNCTSTDITVGTTTQRIETTTDFINVKYTVMQLA 3979
            ....||:.|  |:|.|....:.||::..||           |::...:..|||
Human   897 DLMPGVEYVVTVTAERGRAVSYPASVRANT-----------GSSPLGLLGTTD------------ 938

  Fly  3980 NQTEMRTRFTDIEAENETTGPYTTTTESYKTTKQLSSNPETETPTTLPSRP-------------- 4030
                          |...:||.||         |.:..|      .|..||
Human   939 --------------EPPPSGPSTT---------QGAQAP------LLQQRPQELGELRVLGRDET 974

  Fly  4031 -------TTRPFTDQTTEFTSEIPTITPMEGSTPTPSHLETTVASITSESTTREVYTIKPFD-RS 4087
                   |.:|.|....:....:|     ||   ..:|.|                 :.|.| |.
Human   975 GRLRVVWTAQPDTFAYFQLRMRVP-----EG---PGAHEE-----------------VLPGDVRQ 1014

  Fly  4088 TPTPVSPDTTVPSITFETTTN-IPIGTTRGQ------VTEQTTSSPSEKRTTIRVEESTLPSRST 4145
            ...|..|    |...:|.:.: :|.|.....      :.::....|.:.....|:.|.|:..|::
Human  1015 ALVPPPP----PGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTS 1075

  Fly  4146 D---------------------------RTTPSESPETPTILPSDSTTRTYS------------- 4170
            |                           :..|.|.|:...::.|....|.|.
Human  1076 DSLLLRWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHG 1140

  Fly  4171 ---------DQTTESTRDVPTTRPFEASTPSPASLET--TVPSVTLETTTNDPIGSTGGQVTEQT 4224
                     .|:..|....|.......:.|:|.||..  |||....:|.          .|..:.
Human  1141 PLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTF----------MVQYRD 1195

  Fly  4225 TSSPSEVRTTIGLEESTLPSR-----------------------STDRTTPSESPETPTTLPSDF 4266
            .....:|....|.|.|.:.|.                       :.|.||..|..|.|..  .:|
Human  1196 RDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPR--PEF 1258

  Fly  4267 ITRPHSDQTTESTRDVPTTRPFEASTPSSASLETTVPSVTLET-----------TTNVPIGSTGG 4320
            :.:|...:.|.:           ..||.|..|..||.....::           ...||:.....
Human  1259 LEQPLLGELTVT-----------GVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDEN 1312

  Fly  4321 QVTEQTTSSPSEVRTTI-------RVEESTLPSRSADRTTPSESPETPTTLPSDFTTRPHSEQTT 4378
            :||........:.:..:       ||...::.:::|.:....|:| :||.|.::....|......
Human  1313 EVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETP-SPTELGTEAPESPEEPLLG 1376

  Fly  4379 ESTRDVPTTRPFEASTPSPASLETTVPSVTLETTT-----------NVPIGSTGGQVT------- 4425
            |.|        ...|:|...||..|||..:.::.|           .|.:|....:||
Human  1377 ELT--------VTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPG 1433

  Fly  4426 ------------GQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTTLPSDFITRPHSEK 4478
                        ||.....|.|..|...:|.|.|:        :|||..|..          .|.
Human  1434 HKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPA--------TESPLEPRL----------GEL 1480

  Fly  4479 TTESTRDVPTTRPFEASTPSSASLETTVPSVTLET-----------TTNVPIGSTGGQVTEQTTS 4532
            |   ..||         ||:|..|..|||....::           ...||:.:...:||.....
Human  1481 T---VTDV---------TPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLE 1533

  Fly  4533 SPSEVRTT------------IRVEESTLPSRSADRTTLSESPETPTTLPSDFTIRPHSEQTTEST 4585
            ...:.:..            :.|...|.|...|..|..|:.|           :.|...:.|  .
Human  1534 PERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPP-----------LEPRLGELT--V 1585

  Fly  4586 RDVPTTRPFEASTPSPASLETTVPSVTSET-----------TTNVPIGSTGGQVT---------- 4629
            .|:         ||....|..|||....::           ...||:.:...:||
Human  1586 TDI---------TPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKY 1641

  Fly  4630 ---------GQTTAPPS-EFRTTIRVEES------------------------TLPSRSTD---- 4656
                     |:..:|.| |.:|..|.:.|                        |:|....|
Human  1642 KFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVV 1706

  Fly  4657 --------RTTPSESPE-TPTILPSDSTTRTY-----------------SDQTTESTR---DVPT 4692
                    :..|.|..| :.|:.|.|: .|.|                 :|.|||:..   |..|
Human  1707 QFKDKDGPQVVPVEGHERSVTVTPLDA-GRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGT 1770

  Fly  4693 TRPFEASTPSPASLE----TTVPSVTLETTTNVPIGSTGGQVTE--QTTSSPSEVRTTIRVEEST 4751
            .||     |.|...|    |||...::..:..||.|.....|.:  .....|..|.....:.|.:
Human  1771 KRP-----PKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVS 1830

  Fly  4752 LPSRS-ADR----------------------TTPSESPETPTTLPSDFITRPHSEKTTESTRDVP 4793
            :|... |.|                      |...|..||.||.|:.....||..:.|
Human  1831 VPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELT------- 1888

  Fly  4794 TTRPFEASTPSSASL-----ETTVPSVTLETTTN------VPIGSTGGQVTEQTTSSPSEVRTT- 4846
                .|.:|..:..|     |....|..::.|..      |.||.....:|.....|......|
Human  1889 ----VEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTL 1949

  Fly  4847 -----------IRVEESTLPSRSADRTTPSESPETPTTLPSDFITRPHSEKTTESTRDVPTTRPF 4900
                       :.||..|:|........|:.:||.|        .:|...:.|.:.
Human  1950 YGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPP--------IKPRLGELTVTD--------- 1997

  Fly  4901 EASTPSSASLETTVPSVTLE-------------TTTNVP---------------------IGSTG 4931
              :||.|.||..|||....:             ....||                     .|..|
Human  1998 --ATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHG 2060

  Fly  4932 GQVTEQTTSSPSEVRTTIRVEESTLPSR-STDRTTPSESPETPTTLPSDFTTRPHSEQTTESTRD 4995
            |    |.....|.|..|...||:..|:. |.:...|:|.|     |..:.|.
Human  2061 G----QRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEP-----LLGELTV------------- 2103

  Fly  4996 VPTTRPFEASTPSPASLETTVPSVTLETTT--------NVPIGSTGGQVTEQTTSSPSEVRT--- 5049
                   ..|:|...||..|||....::.|        ...:...||:.:|.|.......|.
Human  2104 -------TGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKM 2161

  Fly  5050 ---TIRVEESTLPSRSADRTTP-SESPETPTTLPSDFITRTYSDQTTESTRDVPTTRPFEASTPS 5110
               .:.......|..:...|.| .|||:.|       :.:....|.|  .||:         |..
Human  2162 HLYGLHEGRRVGPVSAVGVTAPEEESPDAP-------LAKLRLGQMT--VRDI---------TSD 2208

  Fly  5111 PASLETTVPSVTSE-------------TTTNVP---------------------IGSTGGQVTGQ 5141
            ..||..|||....:             ....||                     .|..|||..|.
Human  2209 SLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGP 2273

  Fly  5142 TTAPPSEFRTTIRVEESTLPSRSTDRTTPSESPETPTTLPSDFTTRPHSDQTTESTRDVPTTRPF 5206
            .:|           ...|.|.:..:....|..|.||     :...:|..::.|.:.
Human  2274 VSA-----------VGLTAPGKDEEMAPASTEPPTP-----EPPIKPRLEELTVTD--------- 2313

  Fly  5207 EASTPSPASLETTVPSVTLE-------------TTTNVP---------------------IGSTG 5237
              :||...||..|||....:             ..|.||                     .|..|
Human  2314 --ATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHG 2376

  Fly  5238 GQ-----------VTEQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTLPSDFTTRPHS 5291
            ||           ..|:.|.||:|            ||..|     .|.||.|.|         .
Human  2377 GQRVGPVSAIGVTAAEEETPSPTE------------PSMEA-----PEPPEEPLL---------G 2415

  Fly  5292 EQTTESTRDVPATRPFEASTPSPASLETTVPSVTSEATT--------NVPIGSTGGQVTEQTTSS 5348
            |.|.            ..|:|...||..|||....::.|        ...:...||:.:|.|...
Human  2416 ELTV------------TGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGG 2468

  Fly  5349 PSEVR------------------TTIRVEESTLPSRSTDRT-SPSESPETPTTLPSDFTTRPHSD 5394
            ....|                  :|:.|   |.|....|.| ||:| |.|....|      |...
Human  2469 LEPGRKYKMHLYGLHEGRRVGPVSTVGV---TAPQEDVDETPSPTE-PGTEAPGP------PEEP 2523

  Fly  5395 QTTECTRDVPTTRPFEASTPSSASLETTVPSVTLETTT--------NVPIGSTGGQVTEQTTSSP 5451
            ...|.|        ...|:|.|.||..|||....::.|        .......|||
Human  2524 LLGELT--------VTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQ--------- 2571

  Fly  5452 SEVRTTIRVEESTLPSR----------SADRTTPSESPETPTLPSDFTTRPHSEQTTESTRDVPT 5506
             |.:.|:|..|   |.|          ...|..|..:...            :|...|:|:.|||
Human  2572 -ESKVTVRGLE---PGRKYKMHLYGLHEGRRLGPVSAVGV------------TEDEAETTQAVPT 2620

  Fly  5507 TRP------------FEASTPSSASLETTVPSVTLE-------------TTTNVP---------- 5536
            ..|            ...:||.|.||..|||....:             ....||
Human  2621 MTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISG 2685

  Fly  5537 -----------IGSTGGQ-----------VTEQTTSSPSEFRTTIRVEESTLPSRSADRTTPSES 5579
                       .|..|||           ..|:.|.||:|..|                    |:
Human  2686 LEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELST--------------------EA 2730

  Fly  5580 PETPTLP--SDFTTRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTG 5642
            ||.|..|  .:.|.                    ..|:|...||..|:|....::.| |......
Human  2731 PEPPEEPLLGELTV--------------------TGSSPDSLSLSWTIPQGHFDSFT-VQYKDRD 2774

  Fly  5643 GQVTGQTTAPPSEVRTTIRVEESTLPSRSTDRTTPSESP------------ETPTILPSDSTTRT 5695
            |:        |..:|  :|.|||.:       |.....|            |...:.|..:...|
Human  2775 GR--------PQVMR--VRGEESEV-------TVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVT 2822

  Fly  5696 YSDQTTESTRDVPTTRP------------FEASTPSPASLETTVPSVTLE-------------TT 5735
            ..:...|:|:.||||.|            ...:||...||...||....:             ..
Human  2823 APEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKV 2887

  Fly  5736 TNVP---------------------IGSTGGQVTGQTTATPSEVRTTIGVEESTLPSRSTDRTSP 5779
            ..||                     .|..|||..|     |..|......||.| |:.:...|..
Human  2888 VRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVG-----PISVIGVTAAEEET-PAPTEPSTEA 2946

  Fly  5780 SESPETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGS 5844
            .|.||.|  |..:.|.                    ..|:|...||..|:|....::.|......
Human  2947 PEPPEEP--LLGELTV--------------------TGSSPDSLSLSWTIPQGRFDSFTVQYKDR 2989

  Fly  5845 TGGQVTEQTTSSPSEVRTTIGLE---------------ESTLPSRSTDRTSPSESPET----PTT 5890
            .|.....:.....||| |..|||               :...|..:...|:|.:..||    ||.
Human  2990 DGRPQVVRVRGEESEV-TVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTM 3053

  Fly  5891 LPSDFITRPHSDQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSE-------------TTTNV 5942
            .|...| :|...:.|.:.           :||...||...||....:             ....|
Human  3054 TPEPPI-KPRLGELTVTD-----------ATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRV 3106

  Fly  5943 P---------------------IGSTGGQVTGQTTAPPSEVRTTIGVEESTLPSRSTDRTSPSES 5986
            |                     .|..|||..|..:|        |||.|...||.:...|...|:
Human  3107 PGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSA--------IGVTEEETPSPTEPSTEAPEA 3163

  Fly  5987 PETPT------------------TLPS---DFITRPHSEQ------------------------- 6005
            ||.|.                  |:|.   |..|..:.::
Human  3164 PEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGR 3228

  Fly  6006 -------------------TTESTRDVPTTRPFEASTPSPASLKTTVPSVTSEAT---------- 6041
                               |...|..:||..|.|     |...:..|.:|||::.
Human  3229 KYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVE-----PRLGELAVAAVTSDSVGLSWTVAQGP 3288

  Fly  6042 ---------------TNVPIG------------------------STGQRIGTTPSESPETPTTL 6067
                           ..||:.                        ..|:|.|..|.|:...|.|.
Human  3289 FDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTK 3353

  Fly  6068 PSDFTTRPHSEKTTESTRDVPTTRPFETSTPSPASLETTVPSVTLET-----------TTNVPIG 6121
            ||     |...:.|.:           .:||....|..|||....::           ...||:.
Human  3354 PS-----PRLGELTVT-----------DATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVA 3402

  Fly  6122 STGGQVTEQTTSSPSEVRTTI--RVEESTLPSRSADRTTPSESPETPTLPSDFTTRPHSEQTTES 6184
            :...:||.|......:.|..:  ......|...|||.||.....|.|....:.|.   :|:|:.|
Human  3403 ANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTV---AEETSSS 3464

  Fly  6185 TRDVPTTR--PFEASTPSPASLE---TTVPSVTSETTTNVPIGSTG--------GQVTGQTTAPP 6236
            .|...|..  ||::........:   ..||....:.|..|.....|        |.:.|:...|.
Human  3465 LRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPV 3529

  Fly  6237 SEVRTTIGVEESTLPSRSTDRTSPSESPETPTTLPSDFITRPHSEQTTESTRDVPTTR---PFEA 6298
            |.:..|...|::..|..:.:...|.|.|.......:|  |.|.|.:.:.|....|...   .:|.
Human  3530 SALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTD--TTPDSMRLSWSVAQGPFDSFVVQYED 3592

  Fly  6299 STPSP--------------ASLKTTVP---------------SVTSEATTNV-PIGSTGGQ---- 6329
            :...|              :.|:.:.|               .:::|.||.: |.|.|..:
Human  3593 TNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPR 3657

  Fly  6330 -----VTEQTTSSPSEVRTTIRVE--------ESTL-----PSRSTDRTTPSESPETPTTLPSDF 6376
                 ||:.||||       :|:.        :|.|     ||.||....|....:....:|.
Human  3658 LSQLSVTDVTTSS-------LRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPG-- 3713

  Fly  6377 TTR-----------------------PHS-----------EKTTESTRDVPTTRPFETST----- 6402
             ||                       ||.           ....||.||:..:...|||.
Human  3714 -TRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWM 3777

  Fly  6403 PSPASLETTVPSVTLETTTSVPMGSTGG-----QVTGQTTAPPSEVRTTI---RVEESTLPSRST 6459
            |.|:..::...|..|         :.||     ||.||  |...:::..|   |.|.:.:..|..
Human  3778 PPPSRADSFKVSYQL---------ADGGEPQSVQVDGQ--ARTQKLQGLIPGARYEVTVVSVRGF 3831

  Fly  6460 DRTSP-----SESPETPTTLPSDFITRPHS------EKTTESTRDV----PTTRPFEASTPSSAS 6509
            :.:.|     :..|:.||.|.:..:|...:      .:....|.||    |...|.:|.||.||
Human  3832 EESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSA- 3895

  Fly  6510 SGNNCSISY------FRNHYKCSNRFNRSADRTTPSESPETPTL--PSDFTTRPHSEQTTESTRD 6566
                  :.|      ...:|..:.|..|..:.|:|:....|..|  |.|...:..:.:|...|..
Human  3896 ------VDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWT 3954

  Fly  6567 VPTTRP----FEASTPSPASLETTVPSVTSETTTNVPIGSTGGQVTGQTTAPPSEVRTTIRVEES 6627
            .|..||    ....||...:.|..:|.           |.|..|:.|...:.....|......:|
Human  3955 EPPVRPAGYLLSFHTPGGQNQEILLPG-----------GITSHQLLGLFPSTSYNARLQAMWGQS 4008

  Fly  6628 TLPSRSTDRTT 6638
            .||..||..||
Human  4009 LLPPVSTSFTT 4019

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpy	NP_001260032.1	EGF_3	137..166	CDD:289699
		EGF_CA	212..247	CDD:238011
		EGF_CA	255..>286	CDD:214542
		EGF_CA	298..331	CDD:238011
		EGF_CA	338..373	CDD:238011
		EGF_CA	413..456	CDD:238011
		EGF_CA	457..490	CDD:238011
		EGF_CA	497..>529	CDD:214542
		EGF_CA	580..>612	CDD:214542
		EGF_3	676..702	CDD:289699
		EGF_CA	1022..1056	CDD:214542
		EGF_CA	2227..2260	CDD:238011
		EGF_CA	2393..>2422	CDD:214542	7/11 (64%)
		DUF4758	4088..4282	CDD:292572	44/274 (16%)
		DUF4696	4127..4678	CDD:292395	133/763 (17%)
		DUF4758	4275..4448	CDD:292572	41/220 (19%)
		DUF4758	4377..4574	CDD:292572	48/249 (19%)
		DUF4758	4581..4754	CDD:292572	51/266 (19%)
		DUF4758	4683..4847	CDD:292572	45/218 (21%)
		DUF4758	4785..4964	CDD:292572	44/236 (19%)
		DUF4696	4841..5385	CDD:292395	136/711 (19%)
		DUF4758	4887..5098	CDD:292572	50/260 (19%)
		DUF4758	5193..5371	CDD:292572	48/248 (19%)
		DUF4758	5294..5487	CDD:292572	49/237 (21%)
		DUF4758	5445..5650	CDD:292572	50/273 (18%)
		DUF4758	5700..5877	CDD:292572	49/237 (21%)
		DUF4696	5756..6396	CDD:292395	173/921 (19%)
		DUF4758	5802..5979	CDD:292572	46/229 (20%)
		DUF4758	5964..6171	CDD:292572	59/333 (18%)
		DUF4758	6181..6360	CDD:292572	50/246 (20%)
		DUF4696	6339..6999	CDD:292395	82/387 (21%)
		DUF4758	6662..6839	CDD:292572
		DUF4758	6764..6941	CDD:292572
		DUF4758	6866..7045	CDD:292572
		DUF4758	6968..7179	CDD:292572
		DUF4696	7024..7569	CDD:292395
		DUF4758	7172..7383	CDD:292572
		DUF4696	7330..7964	CDD:292395
		DUF4758	7400..7587	CDD:292572
		DUF4758	7538..7707	CDD:292572
		DUF4758	7798..7979	CDD:292572
		DUF4758	7946..8126	CDD:292572
		YppG	18767..>18832	CDD:290883
		Med25_SD1	18795..18955	CDD:288132
		MISS	19026..19258	CDD:292450
		ZP	22576..22811	CDD:214579
		Zona_pellucida	<22714..22810	CDD:278526
TNXB	NP_001352205.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..57
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..189		10/57 (18%)
		EGF_2	189..213	CDD:285248	7/23 (30%)
		EGF_2	216..244	CDD:285248	11/32 (34%)
		VSP	<254..669	CDD:333463	174/873 (20%)
		EGF_2	621..647	CDD:285248	6/25 (24%)
		fn3	762..831	CDD:306538	17/177 (10%)
		fn3	843..919	CDD:306538	15/99 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	926..956		12/81 (15%)
		fn3	1061..1141	CDD:306538	11/79 (14%)
		FN3	1156..1238	CDD:238020	15/91 (16%)
		fn3	1265..1342	CDD:306538	13/87 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1340..1372		7/32 (22%)
		fn3	1376..1446	CDD:306538	14/77 (18%)
		fn3	1475..1555	CDD:306538	16/101 (16%)
		fn3	1578..1643	CDD:306538	13/75 (17%)
		Cell attachment site. /evidence=ECO:0000255	1666..1668		1/1 (100%)
		fn3	1672..1739	CDD:306538	11/67 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1752..1777		9/29 (31%)
		FN3	1773..1862	CDD:238020	17/93 (18%)
		fn3	1885..1955	CDD:306538	13/80 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1968..1990		6/29 (21%)
		fn3	1988..2061	CDD:306538	13/83 (16%)
		fn3	2099..2169	CDD:306538	14/89 (16%)
		fn3	2198..2268	CDD:306538	13/80 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2281..2304		5/27 (19%)
		fn3	2304..2377	CDD:306538	13/83 (16%)
		fn3	2418..2485	CDD:306538	14/78 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2495..2542		19/64 (30%)
		fn3	2526..2596	CDD:306538	20/90 (22%)
		fn3	2629..2709	CDD:306538	14/79 (18%)
		fn3	2743..2810	CDD:306538	18/104 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2824..2847		7/22 (32%)
		fn3	2845..2925	CDD:306538	14/84 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2933..2969		13/58 (22%)
		fn3	2959..3026	CDD:306538	16/87 (18%)
		fn3	3061..3134	CDD:306538	11/83 (13%)
		fn3	3170..3240	CDD:306538	4/69 (6%)
		fn3	3263..3328	CDD:306538	7/64 (11%)
		fn3	3354..3436	CDD:306538	17/97 (18%)
		fn3	3453..3515	CDD:306538	13/64 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	3536..3559		5/22 (23%)
		fn3	3562..3637	CDD:306538	10/76 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	3636..3662		6/25 (24%)
		fn3	3656..3738	CDD:306538	17/91 (19%)
		fn3	3758..3836	CDD:306538	21/88 (24%)
		FN3	3845..3931	CDD:238020	21/92 (23%)
		fn3	3935..4012	CDD:306538	18/87 (21%)
		Fibrinogen_C	4026..4235	CDD:278572

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910