Protein Alignment dpy and Nolc1

DIOPT Version :9

• Sequence 1: NP_001260032.1
• Gene: dpy / 318824
• FlyBaseID: FBgn0053196
• Length: 22949
• Species: Drosophila melanogaster
• Sequence 2: NP_074060.2
• Gene: Nolc1 / 64896
• RGDID: 621578
• Length: 704
• Species: Rattus norvegicus
• Alignment Length: 778
• Identity: 157/778 - (20%)
• Similarity: 264/778 - (33%)
• Gaps: 203/778 - (26%)

  Fly  4810 TTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTTL 4874
            |..|.|.|:  :|.|:..   :..::|:||.|...::...:::.:|::.|      .:|....:|
  Rat    61 TKAPKVKLQ--SNGPVAK---KAKKETSSSDSSEDSSEEEDKAQVPTQKA------AAPAKRASL 114

  Fly  4875 PSDFITRPHSEKTTESTRDVPTTRPFEASTPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTT 4939
            |.      |:.|..             |....|:|.|.:......|.....|:        :|..
  Rat   115 PQ------HAGKAA-------------AKASESSSSEESSEEEEEEDKKKKPV--------QQKA 152

  Fly  4940 SSP--SEVRTTIRVEESTLPSRSTDRTTPSESPETPTTLPSDFTTRPHSEQTTESTRDVPTTRPF 5002
            ..|  ..||...:..||:  ...:|.::..|:|:         |.:|.:..|....       |.
  Rat   153 VKPQAKAVRPPPKKAESS--ESESDSSSEDEAPQ---------TQKPKAAATAAKA-------PT 199

  Fly  5003 EASTPSPASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTT 5067
            :|.|.:||  :...|:.......|...||:....:..::....|.:......:.|.|.:......
  Rat   200 KAQTKAPA--KPGPPAKAQPKAANGKAGSSSSSSSSSSSDDSEEEKKAAAPLKKTAPKKQVVAKA 262

  Fly  5068 PSESPETPTTLPSDFITRTYSDQTTESTRDVPTTRPFE------ASTPSPASLETTVPSVTSETT 5126
            |.:....||       .::.|.:.:.|..:....:|.:      :|.| |.|:..:..||.:::
  Rat   263 PVKVTAAPT-------QKSSSSEDSSSEEEEEQKKPMKKKAGPYSSVP-PPSVSLSKKSVGAQS- 318

  Fly  5127 TNVPIGSTGGQVTGQTTAPPSEFRTTIRVEESTLPSRSTDRTTPSESPETPTTLPSDFTTRPHSD 5191
               |..:........::|..||...:...||...|:    :|..|::|..|.  |........||
  Rat   319 ---PKKAAAQTQPADSSADSSEESDSSSEEEKKTPA----KTVVSKTPAKPA--PVKKKAESSSD 374

  Fly  5192 QT-TESTRDVPTTRPFEASTPSPASLETTV---PSVTLETTTNVPIGSTGGQVTEQTTSSPSEVR 5252
            .: ::|:.|....:|..| |.||.|.....   |:.....|...|.||.....:.:..||.||..
  Rat   375 SSDSDSSEDEAPAKPVSA-TKSPLSKPAVTPKPPAAKAVATPKQPAGSGQKPQSRKADSSSSEEE 438

  Fly  5253 TTIRVEESTLPSRSADRTTPSESPETPTLPSDFTTRPHSEQTTESTRDVPATRPFEASTPSPASL 5317
            ::...||:|..|                     .|.|.:..|.::...:||.:...|
  Rat   439 SSSSEEEATKKS---------------------VTTPKARVTAKAAPSLPAKQAPRA-------- 474

  Fly  5318 ETTVPSVTSEATTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSTDRTSPSESPETPTT 5382
                                ||..:..:.||.||      .|:.|.|.....:.:...:...||.
  Rat   475 --------------------GGDSSSDSESSSSE------EEKKTPPKPPAKKKAAGAAVPKPTP 513

  Fly  5383 LPSDFTTRPHSDQTTECTRDVPTTRPFEASTPS-SASLETTVPSVTLETTTNVPIGSTGGQVTEQ 5446
            :.........|..::|.:.:....:|...:||. .|.....||:     :.|   |..|.:..|:
  Rat   514 VKKAAAESSSSSSSSEDSSEEEKKKPKSKATPKPQAGKANGVPA-----SQN---GKAGKESEEE 570

  Fly  5447 TTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTLPSDFTTRPHSEQTTESTRDVPTTRPFE 5511
                          ||.|..::.|..|.|....:          |.|:|     |.|       |
  Rat   571 --------------EEDTEQNKKAAGTKPGSGKK----------RKHNE-----TAD-------E 599

  Fly  5512 ASTPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEFRTTIRVEESTLPSRSADRT 5574
            |:||.|       ..|.|:|....|....|    |:..|||  || .:|.||..:.||.||.:
  Rat   600 AATPQS-------KKVKLQTPNTFPKRKKG----EKRASSP--FR-RVREEEIEVDSRVADNS 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpy	NP_001260032.1	EGF_3	137..166	CDD:289699
		EGF_CA	212..247	CDD:238011
		EGF_CA	255..>286	CDD:214542
		EGF_CA	298..331	CDD:238011
		EGF_CA	338..373	CDD:238011
		EGF_CA	413..456	CDD:238011
		EGF_CA	457..490	CDD:238011
		EGF_CA	497..>529	CDD:214542
		EGF_CA	580..>612	CDD:214542
		EGF_3	676..702	CDD:289699
		EGF_CA	1022..1056	CDD:214542
		EGF_CA	2227..2260	CDD:238011
		EGF_CA	2393..>2422	CDD:214542
		DUF4758	4088..4282	CDD:292572
		DUF4696	4127..4678	CDD:292395
		DUF4758	4275..4448	CDD:292572
		DUF4758	4377..4574	CDD:292572
		DUF4758	4581..4754	CDD:292572
		DUF4758	4683..4847	CDD:292572	10/36 (28%)
		DUF4758	4785..4964	CDD:292572	30/155 (19%)
		DUF4696	4841..5385	CDD:292395	102/555 (18%)
		DUF4758	4887..5098	CDD:292572	35/212 (17%)
		DUF4758	5193..5371	CDD:292572	36/181 (20%)
		DUF4758	5294..5487	CDD:292572	33/193 (17%)
		DUF4758	5445..5650	CDD:292572	35/130 (27%)
		DUF4758	5700..5877	CDD:292572
		DUF4696	5756..6396	CDD:292395
		DUF4758	5802..5979	CDD:292572
		DUF4758	5964..6171	CDD:292572
		DUF4758	6181..6360	CDD:292572
		DUF4696	6339..6999	CDD:292395
		DUF4758	6662..6839	CDD:292572
		DUF4758	6764..6941	CDD:292572
		DUF4758	6866..7045	CDD:292572
		DUF4758	6968..7179	CDD:292572
		DUF4696	7024..7569	CDD:292395
		DUF4758	7172..7383	CDD:292572
		DUF4696	7330..7964	CDD:292395
		DUF4758	7400..7587	CDD:292572
		DUF4758	7538..7707	CDD:292572
		DUF4758	7798..7979	CDD:292572
		DUF4758	7946..8126	CDD:292572
		YppG	18767..>18832	CDD:290883
		Med25_SD1	18795..18955	CDD:288132
		MISS	19026..19258	CDD:292450
		ZP	22576..22811	CDD:214579
		Zona_pellucida	<22714..22810	CDD:278526
Nolc1	NP_074060.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..638		150/762 (20%)
		11 X 12 AA approximate repeats of an acidic serine cluster	84..570		115/620 (19%)
		PHA03247	<147..561	CDD:223021	98/523 (19%)
		SRP40_C	629..701	CDD:398615	10/23 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910