DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpy and si:ch211-226h7.3

DIOPT Version :9

Sequence 1:NP_001260032.1 Gene:dpy / 318824 FlyBaseID:FBgn0053196 Length:22949 Species:Drosophila melanogaster
Sequence 2:XP_021336103.1 Gene:si:ch211-226h7.3 / 568241 ZFINID:ZDB-GENE-130531-9 Length:1838 Species:Danio rerio


Alignment Length:2018 Identity:360/2018 - (17%)
Similarity:519/2018 - (25%) Gaps:841/2018 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly 14588 QIIEPPVPPPRQT-C---LPS----PCGPYSQC----REVNESPSCTC----------------- 14623
            ::::|.:..|:.: |   :||    ||..|...    |..|||....|                 
Zfish   142 ELVKPDLSIPKPSYCAVVIPSISSDPCYNYEPLDRPWRANNESGDSLCDDSFTWRGWYRLFYYGM 206

  Fly 14624 ---LPEYIGAPPNC-----------RPE------------------CVTSSECPTN-QAC----- 14650
               :||......||           .|:                  |..|...|.. :||     
Zfish   207 DIRMPETCTTGLNCNTYTNLVLDGSHPQIEDGVVIREVCGSSYWSGCCDSKSIPIRVKACPGNYY 271

  Fly 14651 IQQKCRDPCPGLCGQSAECRVLSHTPSCVCPEGMEGDPFTLCKEKRIQELDQLDPCSPSPCGINA 14715
            :.:..| |..|..|...:...:|...|...|:.:.|...|          ...|||:      |.
Zfish   272 VYELVR-PQMGCSGYCIDVSTISQVVSTASPDIIPGSTIT----------SNYDPCN------NY 319

  Fly 14716 RCTSRQDAGSCQCLPDY-----FGNPYE----------GCRPECVLNSDCPSNKACQQQKCQDPC 14765
            .........:....|.|     |.|.||          |      |::..|           |.|
Zfish   320 NTLDNDWRSTYTYWPVYNDVNGFDNNYEWDGWYRLLMNG------LSAQMP-----------DWC 367

  Fly 14766 PG--TCG--------------------------QNALCNVLNHIPSCSCISGYSGDPYRSCVPEP 14802
            ..  |||                          ::.||:                 .|||     
Zfish   368 ASYMTCGGVTALWLHGSHPRLEDGVVTREVYGSRDNLCS-----------------RYRS----- 410

  Fly 14803 VKEYVNPCQPSPCGPNSQCREVNEQAICSCLPEYVGAPPVCRPECTISSECPADKACVNQKCVDP 14867
                 ||.|...|..:....:.....|....|.|          |.:|...|:         |||
Zfish   411 -----NPIQVKACAGDYYVYKFTRPPISIQAPRY----------CAVSFTTPS---------VDP 451

  Fly 14868 CPNTCGDQAICRVVNHSPICSCRAGYTGDAF---------FRCFPKPPVPPTPVQKTPVDPCV-P 14922
            |.|........|..::.      |.|.|:.|         :|.|........|      |.|| .
Zfish   452 CYNYTSLDEPWRSTDNP------ANYYGNHFDWSVAWNGWYRLFYNNQSAQMP------DSCVNE 504

  Fly 14923 TPCGPYSQCRSQGDAPACS--------CLVGYIGAPPNCRPECRINAECPSSQACINEKCRDPCP 14979
            ..||.|......|..|...        |:..:.|.             |..:...|..|.   ||
Zfish   505 GMCGTYYPLWLNGSHPELEDGVVLRQVCVSAWNGC-------------CTFTSHPIRVKA---CP 553

  Fly 14980 GSCGYGAICNVINHTPSCTCPPGYSGDPFSQCQPV-------PPPPPTPVKLDDPCNPSPCGPNA 15037
            |............|:..|.. ...|....:..||:       ||....||   ||||        
Zfish   554 GDYYVYEFVQPRTHSAYCVA-TNQSSTAVTTTQPITSEEFINPPTTAPPV---DPCN-------- 606

  Fly 15038 QCNNGVCTCIPEYH--GDPYSGCRPECITSADCSRELACSR------------NKCFDPCPGTCA 15088
                       .|.  .||:..      ||...|.:|.|.|            |......|.||.
Zfish   607 -----------NYFILDDPWRA------TSNQNSSQLMCDRAVSWSGWYRLFINGQSVQMPDTCV 654

  Fly 15089 PNAICTVLNHVPMC----------------TCPEGYNGNAFVQCKPTPPPALVQPC--------- 15128
            ....|.  .|.|:.                .|....|...:.|..|..    |:.|         
Zfish   655 DENSCG--THAPLWLSGGHPTLEDGVVTRDVCGHWSNNCCYFQSNPIQ----VKACPGGFYVYEF 713

  Fly 15129 -QPSPCGPNSQCREVNQQAVCSCV---PGYIGTPPLCRPECTSNSECLSHLACVNQKCNDPCPG- 15188
             :|:.|          ..|.|:.|   ..|....|.     |:.:|..:.::.......|||.. 
Zfish   714 VRPTTC----------NLAYCADVRFNTSYTTDTPE-----TTTTETTTTISVHTTSSFDPCHQY 763

  Fly 15189 --------------------------------SCGRNAQCSVVNHNPFCTCLPR-----FTGNPF 15216
                                            ..|::||.|.       .|:..     :||...
Zfish   764 NTLDEYWRNIRIRHYLDHDDTMVEWNGWYRLYLTGQSAQMSE-------WCMSSMGCGGYTGLYL 821

  Fly 15217 VGCQQIIEP--PRQDIVPQDPCRPSPCGP--NSECRAAGETATCTCLGDF-----------VGSP 15266
            .|....:|.  ..:|:|.:: ...:.||.  :|..|..      .|.||:           :..|
Zfish   822 NGSHPTLEDGVVTRDVVGRN-MWSNQCGKYRSSSIRVK------ACPGDYYVYELVKPDLSIPKP 879

  Fly 15267 PYCKPECVANSECPSNLACINQKCRD--------PCPGLCGSSATCR---VVSHTAMCI-----C 15315
            .||.....:.|..|    |.|.:..|        ....||..|.|.|   .:.:..|.|     |
Zfish   880 SYCAVVIPSISSDP----CYNYESLDRPWRANNESGDSLCDDSFTWRGWYRLFYFGMDIRMPETC 940

  Fly 15316 DAGLTGDPFTQC-----QPIVQDVEIINPCQPSPCGANAECIQRNGAGACQ----------CLTD 15365
            ..||..:.:|..     .|.::|..:..    ..||::      ..:|.|.          |..:
Zfish   941 TTGLNCNTYTNLVLDGPHPQIEDGVVTR----EVCGSS------YWSGCCDSKSIPIRVKACPGN 995

  Fly 15366 YF----GNPYEGCRPECVLNSDCPSNRACQQQKCRDPCPGSCGQNAECNVVNHTPMCNCFAGFIG 15426
            |:    ..|..||...|:   |..:..........|..|||       .:.::...||.: ..:.
Zfish   996 YYVYELVRPQMGCSGYCI---DVSTISQVVSTASPDIIPGS-------TITSNYDPCNNY-NTLD 1049

  Fly 15427 DPYR--YCSQPPEPIVHEYVNPCQ----------------PSPCGPNSNCREVN----------- 15462
            :.:|  |...|....|:.|.|..:                |..|.....|..|.           
Zfish  1050 NDWRSTYTYWPVYNDVNGYDNNYEWDGWYRLFMNGLSAQMPDWCASYMTCGGVTALWLHGSHPRL 1114

  Fly 15463 EQAVCSCRSEFEGAPPNCRPQCTSSSECASNRACINQKCVDPCPGVCGQQAICEVRNHSPICRCP 15527
            |..|.:  .|..|:..|.         |:..|:  |...|..|||..                  
Zfish  1115 EDGVVT--REVYGSRDNL---------CSRYRS--NPIQVKACPGYY------------------ 1148

  Fly 15528 TAMIGDPFVRCIPRPTIA-PPPLRDVAPYRDPCLPSPCGLYASC----RNQQNQAVCSCLPNYFG 15587
                   :|....||.|: ..|......:..|.: .||..|.|.    |:..|.|      ||:|
Zfish  1149 -------YVYKFTRPPISIQAPRYCAVSFTTPSV-DPCYNYTSLDEPWRSTDNPA------NYYG 1199

  Fly 15588 TPPHCRPECSIN-----------AECPSHLACIGERCRDPCPGACGQQTECRVISHVPSC----- 15636
            .  |.....:.|           |:.|.  :|:.|       |.||......:....|..     
Zfish  1200 N--HFDWSVAWNGWYRLFYNSQSAQMPD--SCVNE-------GMCGTYYPLWLNGSHPELEDGVV 1253

  Fly 15637 ---VCLRGYVGDAFLACHP----APP--------------------------------------- 15655
               ||:..:.|......||    |.|                                       
Zfish  1254 LRQVCVSAWNGCCTFTSHPIRVKACPGDYYVYEFVQPRTHSAYCVATNQSSTAVTTTQPITSEEF 1318

  Fly 15656 --PPSREEPRDPCN-------PSPCGSNAICSNQGECKCVADYQG-------DPYVACRPECVLS 15704
              ||:.:.|.||||       |....||. .|:|..|.....:.|       ...|.....||..
Zfish  1319 INPPTTDPPVDPCNNYIILDEPWRATSNQ-NSSQLMCDSAVSWSGWYRLFINGQSVQMPDTCVDE 1382

  Fly 15705 SECPR---------------------------NLAC------IQQKCTDPCPG-----------T 15725
            :.|..                           |..|      ||.|.   |||           |
Zfish  1383 NSCGTHAPLWLSGGHPTLEDGVVTRDVCGHWGNNCCYFQSNPIQVKA---CPGGFYVYEFVRPTT 1444

  Fly 15726 CGTNAICDVVNHIAMCHCPDRMTGNAFVQCTP--------VQLDVYRNPCNPSPCGSYAECREQN 15782
            |.            :.:|.|.....::...||        ..:...||||:...|.....|..:|
Zfish  1445 CN------------LAYCADVRFNTSYTTDTPETTTTETTTTISDDRNPCSELNCSKEERCGMKN 1497

  Fly 15783 GQAVCSCLPNYFGVPPSCRPECSTNYDCSPSLACQNQRCVDPCPGACGAYAECRTVNHSPFCSCR 15847
            |...|.|...:..     ......::|.:           :.|..:.|:.:..|           
Zfish  1498 GVYGCLCNKGHHK-----HRAAQDSFDFN-----------ETCESSSGSMSVSR----------- 1535

  Fly 15848 PGYTGNPIVQCHMIIEPQRDITPKDPCQPSPCGPNSECRRVGETPSCSCLSNFFGTPPNCRPECV 15912
                                      ||....|.::|...:.: |||.      ||..|.|.|  
Zfish  1536 --------------------------CQLFEAGFSAEHLHLND-PSCR------GTVQNGRVE-- 1565

  Fly 15913 SNSECSQVHVCSNNRCKD-----------PCPGLCGTDAVCRVISHSAMCYCQPGYSGDPFVRCA 15966
            .|.:..| |:|..|...:           ..||..|..:..|::..|..|.              
Zfish  1566 FNFDNDQ-HICGTNLVANGSHFIYSNYIVGTPGTEGLISRVRILKLSFSCV-------------- 1615

  Fly 15967 PHIQRESIEIVQPCNPNPCGAFAECRQQNGVGSCQCLP---EYFGNPYEGCRPECVLDSDCPSQL 16028
             :.|.:::.:....||.............||...:.:|   |.|..|:.| |.:..||.:...::
Zfish  1616 -YPQTQTLSMNVEINPLQSTVHKVLPSGEGVYQVRMVPYVDEEFTQPFTG-RVDAELDQEMHVEV 1678

  Fly 16029 ACVNQKCR------DPCPGSCGQNAECFVRNHLPTCNCLSGYVGDPYRYCSIEPKPIREYVNPCQ 16087
            .......|      |.|..:...:.:..:|..|.|..|               |.|..:.|... 
Zfish  1679 GVEGVDSRQFALVMDTCWATPVNDPDYSLRWDLITEGC---------------PNPEDDTVKLL- 1727

  Fly 16088 PSPCGPNSQCREQNGVATCS--CLPEFVGTPPGCRPECTVSSECNLDKACVRHKCL---DPCPGA 16147
                        ||||:|.|  ....|:.|          ::...|...|..|.||   :.|..:
Zfish  1728 ------------QNGVSTSSRFSFRMFIFT----------ANSTKLYLHCAVHLCLLSSEQCSTS 1770

  Fly 16148 CGS 16150
            |.|
Zfish  1771 CDS 1773

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpyNP_001260032.1 EGF_3 137..166 CDD:289699
EGF_CA 212..247 CDD:238011
EGF_CA 255..>286 CDD:214542
EGF_CA 298..331 CDD:238011
EGF_CA 338..373 CDD:238011
EGF_CA 413..456 CDD:238011
EGF_CA 457..490 CDD:238011
EGF_CA 497..>529 CDD:214542
EGF_CA 580..>612 CDD:214542
EGF_3 676..702 CDD:289699
EGF_CA 1022..1056 CDD:214542
EGF_CA 2227..2260 CDD:238011
EGF_CA 2393..>2422 CDD:214542
DUF4758 4088..4282 CDD:292572
DUF4696 4127..4678 CDD:292395
DUF4758 4275..4448 CDD:292572
DUF4758 4377..4574 CDD:292572
DUF4758 4581..4754 CDD:292572
DUF4758 4683..4847 CDD:292572
DUF4758 4785..4964 CDD:292572
DUF4696 4841..5385 CDD:292395
DUF4758 4887..5098 CDD:292572
DUF4758 5193..5371 CDD:292572
DUF4758 5294..5487 CDD:292572
DUF4758 5445..5650 CDD:292572
DUF4758 5700..5877 CDD:292572
DUF4696 5756..6396 CDD:292395
DUF4758 5802..5979 CDD:292572
DUF4758 5964..6171 CDD:292572
DUF4758 6181..6360 CDD:292572
DUF4696 6339..6999 CDD:292395
DUF4758 6662..6839 CDD:292572
DUF4758 6764..6941 CDD:292572
DUF4758 6866..7045 CDD:292572
DUF4758 6968..7179 CDD:292572
DUF4696 7024..7569 CDD:292395
DUF4758 7172..7383 CDD:292572
DUF4696 7330..7964 CDD:292395
DUF4758 7400..7587 CDD:292572
DUF4758 7538..7707 CDD:292572
DUF4758 7798..7979 CDD:292572
DUF4758 7946..8126 CDD:292572
YppG 18767..>18832 CDD:290883
Med25_SD1 18795..18955 CDD:288132
MISS 19026..19258 CDD:292450
ZP 22576..22811 CDD:214579
Zona_pellucida <22714..22810 CDD:278526
si:ch211-226h7.3XP_021336103.1 ZP 1535..1773 CDD:214579 62/338 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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