Protein Alignment dpy and MUC2

DIOPT Version :9

• Sequence 1: NP_001260032.1
• Gene: dpy / 318824
• FlyBaseID: FBgn0053196
• Length: 22949
• Species: Drosophila melanogaster
• Sequence 2: NP_002448.4
• Gene: MUC2 / 4583
• HGNCID: 7512
• Length: 5289
• Species: Homo sapiens
• Alignment Length: 7210
• Identity: 1709/7210 - (23%)
• Similarity: 2319/7210 - (32%)
• Gaps: 2600/7210 - (36%)

  Fly  2755 RDAPCGPGARCRNARG--SYKCTCPPGLVGDPYNEG-----CRSSVECETNED------CPPH-A 2805
            |:..||   .|.:..|  ||......|::..|...|     .:..|.||..|:      |..| |
Human   162 RNHTCG---LCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRA 223

  Fly  2806 ACTK---TNGVAKCRDV---------CAQLQCGPNAECVPKGHVAQCACRSGYDGQPADRVAGCK 2858
            .|.:   ....|.|:|:         |.|.:|    .| |.|....|:..:.:..|.:.  ||.:
Human   224 ECERLLTAEAFADCQDLVPLEPYLRACQQDRC----RC-PGGDTCVCSTVAEFSRQCSH--AGGR 281

  Fly  2859 PLPSPCQVTGDCPTNTYCSDSVCKPACVLDTECGAFEVCQGGQCFNPCLQPQACGQNAECVMQNH 2923
            |        |:..|.|.| ...| |..::..|.|           :||:...:..:.:....::.
Human   282 P--------GNWRTATLC-PKTC-PGNLVYLESG-----------SPCMDTCSHLEVSSLCEEHR 325

  Fly  2924 LKQCHCPEGFTGDSAKECVRVPVACDGECGPGYTCRDSMCLPV--CH---------------NDL 2971
            :..|.||||...|              :.|      ||.|:||  ||               ||.
Human   326 MDGCFCPEGTVYD--------------DIG------DSGCVPVSQCHCRLHGHLYTPGQEITNDC 370

  Fly  2972 E-CASNE---KCLKGSCMLTCRVDNDCFLGHV--------CLHNKCVY----GCHVDDDCSASES 3020
            | |..|.   .|....|..||.::..   .|:        ..|..|.|    |.|.|......|.
Human   371 EQCVCNAGRWVCKDLPCPGTCALEGG---SHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGEL 432

  Fly  3021 CRNDKCVNPCLENPCGPNAACSVSNHRASCSCLESMVPNPTPQVGCVRSPPLECRENRDCGNGLA 3085
            .            |||                       .|.:..|:::..|...:.::    :.
Human   433 A------------PCG-----------------------STDKQTCLKTVVLLADKKKN----VV 458

  Fly  3086 CFESVCRPLCADDAGCLTNE--------RCQQGVCKPLCRHDNECGHGELCLGLNCVPGCRSDQG 3142
            .|:|        |...|.||        .....|.:|...|          :.::...|.|
Human   459 VFKS--------DGSVLLNELQVNLPHVTASFSVFRPSSYH----------IMVSMAIGVR---- 501

  Fly  3143 CPPELSCVGQQCVDPCADPTACGTNAHCQTIDHRKQCLCPEGLDGNANVACKVPRIACGRNEDCQ 3207
            ...:|:.|.|..|                |:|...|
Human   502 LQVQLAPVMQLFV----------------TLDQASQ----------------------------- 521

  Fly  3208 SNQLCYAGSCQGKCRNDQNCLADERCMRGTCRTVCNTDEACAQGQICENRMCQTGCRTDLSCATD 3272
                   |..||.|.|......|:      .:|.....||...| .......|:.|...|....|
Human   522 -------GQVQGLCGNFNGLEGDD------FKTASGLVEATGAG-FANTWKAQSSCHDKLDWLDD 572

  Fly  3273 EACVN--------------KKCQNPCRTPGQCGQCADCLVVNHGVQCQCPAAFMGDGLTGCQLPP 3323
            ...:|              ||.:.|.   |:|....|            ||.:.
Human   573 PCSLNIESANYAEHWCSLLKKTETPF---GRCHSAVD------------PAEYY----------- 611

  Fly  3324 ERCHPD-CECDENGAYCAPKCSRTEDCAC------GQQC-ARG---------KCRNKCG--PKRQ 3369
            :||..| |.|..|           |||.|      .:.| |:|         .|....|  |..|
Human   612 KRCKYDTCNCQNN-----------EDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQ 665

  Fly  3370 CTVGQLCERGACIAGCKSNGDCAADQSCVNGKCSDPCANEKACGRNALCTVSEHRMLCYCPDGYE 3434
            ..:..|.   .|...|:|..:  ||..|:.|     .|....||               |||...
Human   666 VFLYNLT---TCQQTCRSLSE--ADSHCLEG-----FAPVDGCG---------------CPDHTF 705

  Fly  3435 GEPSKECVQF-ECRV----------DTDCDSNKRCDQGKCRNPCLEYGACGTNAQCRVVGRKAQC 3488
            .:....||.. :|..          |......:||   .||:..|.   |   .|.|::|:  .|
Human   706 LDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERC---VCRDGRLH---C---RQIRLIGQ--SC 759

  Fly  3489 SCPPDFFGNPTSECRPLEGGCSSKPCGENSKCTEVPGGY-------ECACMDGCIGDAHQGCLCG 3546
            :.|....     :|..|....:|||  ....|..:..||       .|.|.||.:.|...||:.
Human   760 TAPKIHM-----DCSNLTALATSKP--RALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVV- 816

  Fly  3547 GPLVNACRDQPCGLNAACHVLENNQAECYCPEDFPNGDAYVQCYLTTPKQDCRTLGCEVGGCVRQ 3611
                                    :.||.|..   |.|.|...  ...|.||.|..|:.|
Human   817 ------------------------EKECPCVH---NNDLYSSG--AKIKVDCNTCTCKRG----- 847

  Fly  3612 GYEYVCQQDTEQC------------------YSDTDCPSEKSCLQGHCSDPCTMRGVCGLN-ALC 3657
              .:||.|..  |                  |.|.|         |||| ...::..||.| :|.
Human   848 --RWVCTQAV--CHGTCSIYGSGHYITFDGKYYDFD---------GHCS-YVAVQDYCGQNSSLG 898

  Fly  3658 KTVLHRPRCSCPSCHIGRPEIECKSDPKCVAEDTDPK--TKEQIPCSTDS---ECPETLQCGQY- 3716
            ...:......|     |...:.|....|.....|:.|  .|.::....|.   ....|.:.|||
Human   899 SFSIITENVPC-----GTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYL 958

  Fly  3717 ---------------------------GQCTDPCNNPLFICESNKKCETRRHQPVCICKSGFIVN 3754
                                       |.....|.|  |...||....||.|..|.
Human   959 VVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGN--FDHRSNNDFTTRDHMVVS--------- 1012

  Fly  3755 EYGELTCAPDKRECYRDDDCASNMACSDGKCRNPCIVPLGRAAICAENKSCEVQNHKPVCICMR- 3818
              .||......:|.....|.::|        ..||.:...|.: .|| |.|.:.......||..
Human  1013 --SELDFGNSWKEAPTCPDVSTN--------PEPCSLNPHRRS-WAE-KQCSILKSSVFSICHSK 1065

  Fly  3819 -DCQPSISICLRDA-GCPASQACRKLKCVDPCEFA-TCAPNSPCIVEDHKPICK-FCPAGFIADA 3879
             |.:|....|:.|: .|.....| :..|.....:| .|.....|:......:|. ||.   ..:.
Human  1066 VDPKPFYEACVHDSCSCDTGGDC-ECFCSAVASYAQECTKEGACVFWRTPDLCPIFCD---YYNP 1126

  Fly  3880 KNGCQ-KAKPGGNCTSNTDCSQAHQCGS--SGKCIDPCLTSCAGG--------VKCVVSAHRVTI 3933
            .:.|: ..:|.||.:..| |...:...|  |...::.|...|...        .|||.:..
Human  1127 PHECEWHYEPCGNRSFET-CRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADK---- 1186

  Fly  3934 CTC-------PATLTNNTDSNCTSTDITVGTTTQRIETTTDFINVKYTVMQLANQTEMRTRFTDI 3991
            |.|       |...:..|:..|.|.          :.|.:..:..:....::.|||:     ...
Human  1187 CGCYVEDTHYPPGASVPTEETCKSC----------VCTNSSQVVCRPEEGKILNQTQ-----DGA 1236

  Fly  3992 EAENETTGPYTTTTESYKTTKQLSSNPE---TETPTTLPSRPTTRPFTDQTTEFTSEIPTITPME 4053
            ....|..|| ..|.|.:.....:::.|.   |.|..|||:.|||  ||..||..|   ||.:.:.
Human  1237 FCYWEICGP-NGTVEKHFNICSITTRPSTLTTFTTITLPTTPTT--FTTTTTTTT---PTSSTVL 1295

  Fly  4054 GSTPT-----PSHLETTVASITSESTTREVY---TIKPFD---RSTPTP----------VSPDTT 4097
            .:||.     ...:.....|..|:...||.:   ...|.|   ||...|          |..|.:
Human  1296 STTPKLCCLWSDWINEDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQCDVS 1360

  Fly  4098 VPSI--TFETTTNIPIGTTRGQVTEQTTSSPSEKRTTIRVEESTLPSRSTDRTTPSESPETPTIL 4160
            |..|  ..:...|.|.|.............|.:|..       |.||..|  ||||..|.:.|.|
Human  1361 VGFICKNEDQFGNGPFGLCYDYKIRVNCCWPMDKCI-------TTPSPPT--TTPSPPPTSTTTL 1416

  Fly  4161 PSDSTTRTYSDQTTESTRDVPTTRPFEASTPSPASLETTVPSVTLETTTNDPIGSTGGQVTEQTT 4225
            |   .|.|.|..||.:|...|||      ||||....||.|..|  ||.:.||.:|       ||
Human  1417 P---PTTTPSPPTTTTTTPPPTT------TPSPPITTTTTPPPT--TTPSPPISTT-------TT 1463

  Fly  4226 SSPSEVRTTIGLEESTLPSRSTDRTTPSESPETPTTLPSDFITRPHSDQTTESTRDVPTTRPFEA 4290
            ..|:                    ||||    .|||.||...|.| |..||.:|...|||.|
Human  1464 PPPT--------------------TTPS----PPTTTPSPPTTTP-SPPTTTTTTPPPTTTP--- 1500

  Fly  4291 STPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTTPS 4355
            |.|      ||.|.....:||.:|..:|....|..||:.|              |:     ||||
Human  1501 SPP------TTTPITPPASTTTLPPTTTPSPPTTTTTTPP--------------PT-----TTPS 1540

  Fly  4356 ESPETPTTLPSDFTTRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTLETTTNVPIGST 4420
            ....||.|.|:..||.|.:  ||.|.....||.|...:||||.:  ||.||....|||..|
Human  1541 PPTTTPITPPTSTTTLPPT--TTPSPPPTTTTTPPPTTTPSPPT--TTTPSPPTITTTTPP---- 1597

  Fly  4421 GGQVTGQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTTLPSDFITRPHSEKTTESTRD 4485
                   .|::||...||     :|.|..:   ||||....||.|.|:...|.|.:  ||.|...
Human  1598 -------PTTTPSPPTTT-----TTTPPPT---TTPSPPTTTPITPPTSTTTLPPT--TTPSPPP 1645

  Fly  4486 VPTTRPFEASTPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPS 4550
            ..||.|...:|||..:  ||.||..:.|||..|           .|::||...||
Human  1646 TTTTTPPPTTTPSPPT--TTTPSPPITTTTTPP-----------PTTTPSSPITT---------- 1687

  Fly  4551 RSADRTTLSESPETPTTLPSDFTIRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSET 4615
                      :|..|||     |:...|..||.|:....||.|...:||||.....|.||.|  |
Human  1688 ----------TPSPPTT-----TMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT--T 1735

  Fly  4616 TTNVPIGSTGGQVTGQTTAPPSEFRTTIRVEESTLPSRSTDRTTPSESPETPTILPSDSTTRTYS 4680
            |.:.|       .|..||.||                      |.:.||.|.|.||...|..|:|
Human  1736 TPSPP-------TTTMTTLPP----------------------TTTSSPLTTTPLPPSITPPTFS 1771

  Fly  4681 DQTTESTRDVPTTRPFEASTPSPASLETTVPSVTLETTT-------------------------- 4719
                          ||..:||       |.|.|.|...|
Human  1772 --------------PFSTTTP-------TTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGP 1815

  Fly  4720 --------------NVPIGSTG---------GQVTEQTTSSPSEV-------RTTIRV---EEST 4751
                          :||||..|         |.:.:.....|..|       ...|.|   |..|
Human  1816 GWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVT 1880

  Fly  4752 LPSRSADRTTPSESPETPTTLPSDFITRPHSEKTTESTRDVPTTRPFEASTPSSASLETTVPSVT 4816
            .|:...  ||.:|:| |||.:             |.:|...||      .||:|....|..|..|
Human  1881 QPTTMT--TTTTENP-TPTPI-------------TTTTTVTPT------PTPTSTQSTTPTPITT 1923

  Fly  4817 LETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTTPS---ESPETPTTLPSDF 4878
            ..|.|..|. .||.|     |.:|:.:.||..:            .||:   .|.:|||..|.
Human  1924 TNTVTPTPT-PTGTQ-----TPTPTPITTTTTM------------VTPTPTITSTQTPTPTPI-- 1968

  Fly  4879 ITRPHSEKTTESTRDVPTTRPFEASTPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPS 4943
                    ||.:....||....:.:||:|.:..|||      |.|..|.|      |:..|::|.
Human  1969 --------TTTTVTPTPTPTSTQRTTPTSITTTTTV------TPTPTPTG------TQTPTTTPI 2013

  Fly  4944 EVRTTIRVEESTLPSRSTDRTTPSESP---ETPTTLPSDFTTRPHSEQTTESTRDVPTTRPFEAS 5005
            ...||:               ||:.:|   :||||.|.         .||......||....:..
Human  2014 TTTTTV---------------TPTPTPTGTQTPTTTPI---------STTTMVTPTPTPTGTQTL 2054

  Fly  5006 TPSPASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTTPSE 5070
            ||:|.:..|||      |.|..|.|      |:..||:|....||:               ||:.
Human  2055 TPTPITTTTTV------TPTPTPTG------TQTPTSTPISTTTTV---------------TPTP 2092

  Fly  5071 SP---ETPTTLPSDFITRTYSDQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIG 5132
            :|   :|||..|           .|.:|...||..|....||      ||.|..|:.|.|..|
Human  2093 TPTGTQTPTLTP-----------ITTTTTVTPTPTPTGTQTP------TTTPITTTTTVTPTP-- 2138

  Fly  5133 STGGQVTGQTTAPPSEFRTTIRVEESTLPSRSTDRTTPSESPETPTTLPSDFTTRPHSDQTTEST 5197
                ..||..:..|:...||..|..          |.|....:||||.|           .|.:|
Human  2139 ----TPTGTKSTTPTSITTTTMVTP----------TPPPTGTQTPTTTP-----------ITTTT 2178

  Fly  5198 RDVPTTRPFEASTPSPASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTL 5262
            ...||..|....||:|..:.||    |..|.|..|.|      |:..||:|....||:
Human  2179 TVTPTPTPTGTQTPTPTPITTT----TTVTPTPTPTG------TQTPTSTPITTNTTV------- 2226

  Fly  5263 PSRSADRTTPSESPETPTLPSDFTTRPHSEQTTESTRDVPATRPFEAS-----TPSPASLETTVP 5322
                ....||:.:|.|...|...||......|...|: .|.:.|...:     ||:|...:|..|
Human  2227 ----TPTPTPTGTPSTTLTPITTTTMVTPTPTPTGTQ-TPTSTPISTTTTVTPTPTPTGTQTPTP 2286

  Fly  5323 SVTSEATTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSTDRTSPSESP---ETPTTLP 5384
            :..|..||..|            |.:|:..:|     .:|.|..:|...:|:.:|   :||||.|
Human  2287 TPISTTTTVTP------------TPTPTSTQT-----PTTTPITTTTTVTPNPTPTGTQTPTTTP 2334

  Fly  5385 SDFTTRPHSDQTTECTRDVPTTRPFEASTPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTS 5449
              .||      ||..|   ||..|....||::..:.||    |..|.|..|.|:       ||
Human  2335 --ITT------TTTVT---PTPTPTGTQTPTTTPISTT----TTVTPTPTPTGT-------QT-- 2375

  Fly  5450 SPSEVRTTIRVEESTLPSRSADRTTPSESPETPTLPSDFTTRPHSEQTTESTRDVPTTRPFEAST 5514
                            |:.:|..||.:.:| ||| |:. |..|.|...|.:|...||..|....|
Human  2376 ----------------PTTTAITTTTTVTP-TPT-PTG-TQTPTSTPITTTTTVTPTPTPTGTQT 2421

  Fly  5515 PSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEFRTTIRVEESTLPSRSADRTTPSES 5579
            |:|    |.:.:.|..|.|..|.|:....||..||:      ||:               ||:.:
Human  2422 PTS----TPISNTTTVTPTPTPTGTQTPTVTPITTT------TTV---------------TPTRT 2461

  Fly  5580 P--ETPTLPSDFTTRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTG 5642
            |  ...|.|:..||         :|...||..|....||      ||.|..|:.|.|..|
Human  2462 PTGTKSTTPTSITT---------TTMVTPTPTPTGTHTP------TTTPITTTTTVTPTP----- 2506

  Fly  5643 GQVTGQTTAPPSEVRTTIRVEESTLPSRSTDRTTPSESP---ETPTILPSDSTTRTYSDQTTEST 5704
             ..||..|..|:.:.||..|             ||:.:|   :|||..|. :||.|.:...|.:.
Human  2507 -TPTGTQTPTPTPITTTTTV-------------TPTPTPTGTQTPTSTPI-TTTTTVTPTPTPTG 2556

  Fly  5705 RDVPTTRPFEAS---TPSPASLETTVPSVTLETTTNVPIGSTGGQVTGQTTATPSEVRTTI---- 5762
            ...|||.|...:   ||:|....|..|:..|.|||.....:.....|..||.||....||:
Human  2557 TQTPTTTPITTNTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTPTP 2621

  Fly  5763 ---GVEESTL-PSRSTDRTSPSESP---ETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFEASTP 5820
               |.:.:|| |..:|...:|:.:|   :||||.|...||..           :||..|....||
Human  2622 TPTGTQSTTLTPITTTTTVTPTPTPTGTQTPTTTPISTTTTV-----------IPTPTPTGTQTP 2675

  Fly  5821 SPASLETTVPSVTSETTTNVPIGSTGGQVTEQTTSSPSEVRTTIGLEESTLPSRSTDRTSPSESP 5885
            :...:.||    |:.|.|..|.|      |:..||:|....||:               :|:.:|
Human  2676 TSTPITTT----TTVTPTPTPTG------TQTPTSTPISTTTTV---------------TPTATP 2715

  Fly  5886 ---ETPTTLPSDFITRPHSDQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGST 5947
               :|||..|   ||      ||.:....||....:..||:|.:..|||....:.|:|..|   |
Human  2716 TGTQTPTLTP---IT------TTTTVTSTPTPTGTQTPTPTPITTTTTVTPTPTPTSTQTP---T 2768

  Fly  5948 GGQVTGQTTAPPSEVRTTIGVEESTLPSRSTDRTSPSESPETPTTLPSDFITRPHSEQTTESTRD 6012
            ...:|..||..|:...|                     ..:||||        .|...||..|
Human  2769 STPITTTTTVTPTPTPT---------------------GTQTPTT--------THITTTTTVT-- 2802

  Fly  6013 VPTTRPFEASTPSPASLKTTVPSVTSEATTNVPIGSTGQRIGTTPSESPETPTTLPSDFTTRPHS 6077
             ||..|.....|:|.::.||    |:...|..|.|:             :||||.|
Human  2803 -PTPTPTGTQAPTPTAITTT----TTVTPTPTPTGT-------------QTPTTTP--------- 2840

  Fly  6078 EKTTESTRDVPTTRPFETSTPSPASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTI 6142
              .|.:|...||..|..|.:|:|.::.||    |..|.|..|.|      |:..|::|....||:
Human  2841 --ITTTTTVTPTPTPTGTQSPTPTAITTT----TTVTPTPTPTG------TQTPTTTPITTTTTV 2893

  Fly  6143 RVEESTLPSRSADRTTPSESPETPTLPSDFTTRPHSEQTTESTRDVPTTRPFEASTPSPASLETT 6207
                           ||     |||        |...|:|..|....||......||:.....|:
Human  2894 ---------------TP-----TPT--------PTGTQSTTLTPITTTTTVTPIPTPTGTQTPTS 2930

  Fly  6208 VPSVTSETTTNVPIGSTGGQVTGQTTAPPSEVRTTIGVEESTLPSRSTDRTSPSESPETPTTLPS 6272
            .|..|:.|.|..|      ..||..|..|:.:.||..|..:..|:          ..:||||.|
Human  2931 TPITTTITVTPTP------TPTGTQTPTPTPISTTTTVTPTPTPT----------GTQTPTTTP- 2978

  Fly  6273 DFITRPHSEQTTESTRDVPTTRPFEASTPSPASLKTTVPSVTSEATTNVPIGSTGGQVTEQTTSS 6337
                      .|.:|...||..|....||:...:.||    |:...|..|.|      |:..||:
Human  2979 ----------ITTTTTVTPTPTPTGTQTPTTTPISTT----TTVTPTPTPTG------TQTPTST 3023

  Fly  6338 PSEVRTTIRVEESTLPSRSTDRTTPSESP---ETPTTLPSDFTTRPHSEKTTESTRDVPTTRPFE 6399
            |....||:               ||:.:|   :|||..|           .|.:|...||..|..
Human  3024 PITTTTTV---------------TPTPTPTGTQTPTPTP-----------ITTTTTVTPTPTPTG 3062

  Fly  6400 TSTPSPASLETTVPSVTLETTTSVPMGSTGGQVTGQTTAPPSEVRTTIRVEESTLPSRSTDRTSP 6464
            |.||      |:.|..|..|.|..|      ..||..|..|:.:.||..|..:..|:
Human  3063 TQTP------TSTPITTTTTVTPTP------TPTGTQTPTPTPITTTTTVTPTPTPT-------- 3107

  Fly  6465 SESPETPTTLPSDFITRPHSEKTTESTRDVPTTRPFEASTPSSASSGNNCSISYFRNHYKCSNRF 6529
              ..:|||:.|           .|.:|...||..|....||:
Human  3108 --GTQTPTSTP-----------ITTTTTVTPTPTPTGTQTPT----------------------- 3136

  Fly  6530 NRSADRTTPSESPETPTLPSDFTTRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSET 6594
                  |||..:..|.| |   |..|...|:|..|....||......||:.....|:.|..|:.|
Human  3137 ------TTPITTTTTVT-P---TPTPTGTQSTTLTPITTTTTVTPTPTPTGTQTPTSTPITTTTT 3191

  Fly  6595 TTNVPIGSTGGQVTGQTTAPPSEVRTTIRVEESTLPSRSTDRTTPSESP---ETPTILPSDFTTR 6656
            .|..|        ||..|..|:.:.||..|             ||:.:|   :|||:.|
Human  3192 VTPTP--------TGTQTPTPTPISTTTTV-------------TPTPTPTGTQTPTMTP------ 3229

  Fly  6657 PHSDQTTESTRDVPTTRPFEASTPRPVTLETAVPSVTLETTTNVPIGSTGGQVTGQTTATPSEVR 6721
                 .|.:|...||..|....||               |||  ||.:|       ||.||:...
Human  3230 -----ITTTTTVTPTPTPTGTQTP---------------TTT--PISTT-------TTVTPTPTP 3265

  Fly  6722 TTIRVEESTLPSRSTDRTTPSESP---ETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFEASTPS 6783
            |..:...|| |..:|...||:.:|   :||||.|...||               |..|    ||:
Human  3266 TGTQTPTST-PITTTTTVTPTPTPTGTQTPTTTPITTTT---------------TVTP----TPT 3310

  Fly  6784 PASLETTVPSVTSETTTNVPIGSTGGQVTEQTTSSPSEVRTTIGLEESTLPSRSTDRTSPSESP- 6847
            |...::|..:..:.|||..|..:..|  |:..|.:|....||:               :|:.:|
Human  3311 PTGTQSTTLTPITTTTTVTPTPTPTG--TQTPTPTPISTTTTV---------------TPTPTPT 3358

  Fly  6848 --ETPTTLPSDFITRPHSDQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTG 6910
              :||||.|           .|.:|...||..|....||:...:.||    |:.|.|..|.|
Human  3359 GTQTPTTTP-----------ITTTTTVTPTPTPTGTQTPTTTPISTT----TTVTPTPTPTG--- 3405

  Fly  6911 GQVTEQTTSSPSEVRTTIGLEESTLPSRSTDRTSPSESP---ETPTTLPSDFITRPHSDQTTEST 6972
               |:..||:|....||:               :|:.:|   :||||.|   ||      ||.:.
Human  3406 ---TQTPTSTPITTTTTV---------------TPTPTPTGTQTPTTTP---IT------TTTTV 3443

  Fly  6973 RDVPTTRPFEASTPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTL 7037
            ...||....:|.||::.:..|||      |.|..|.|      |:..|::|  :.||..|..:..
Human  3444 TPTPTPTGTQAPTPTAITTTTTV------TPTPTPTG------TQTPTTTP--ITTTTMVTPTPT 3494

  Fly  7038 PSRSTDRTTPSESPETPTTLPSDFTTRPHSDQTTESSRDVPTTQPFEASTPRPVTLQTAVLPVTS 7102
            |   |...||:.:|.|.||     |..|           .||....:..||.|::..|.|.|..:
Human  3495 P---TGTQTPTSTPITTTT-----TVTP-----------TPTPTGTQTPTPTPISTTTTVTPTPT 3540

  Fly  7103 ETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSTDRTTPSESP---ETPTTLPSDFT 7164
            .|.|..|            |::|....||:               ||:.:|   :||||.|...|
Human  3541 PTGTQTP------------TTTPITTTTTV---------------TPTPTPTGTQTPTTTPISTT 3578

  Fly  7165 TRPHSDQTTESSRDVPTTQPFESSTP--RPVTLETAVPPVTSETTTNVPIGSTGGQVTEQTTPSP 7227
            |..           .||..|..:.||  .|:|..|.|.|..:.|.|..|   |...:|..||.:|
Human  3579 TTV-----------TPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTP---TPTPITTTTTVTP 3629

  Fly  7228 SEVRTTIRIEESTFPSRSTDRTTPSESP---ETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFES 7289
            :...|..:...|| |..:|...||:.:|   :||||.|.         .||.:....||....:|
Human  3630 TPTPTGTQTPTST-PITTTTTVTPTPTPTGTQTPTTTPI---------TTTTTVTPTPTPTGTQS 3684

  Fly  7290 STPRPVTLEIAVPPVTSETTTNVAIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSTDRTTPS 7354
            :|..|:|....|.|..:.|.|..   .|...:|..||.:|:...|..:....| |..:|...||:
Human  3685 TTLTPITTTTTVTPTPTPTGTQT---PTSTPITTTTTVTPTPTPTGTQTPTPT-PISTTSTVTPT 3745

  Fly  7355 ESP---ETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFEAS---TPSPASLETTVPSVT-LETTT 7412
            .:|   :|||..|...||......|...|: .||:.|...:   ||:|....|..|::| :.|||
Human  3746 PTPTGTQTPTMTPITTTTTVTPTPTPTGTQ-TPTSTPITTTTTVTPTPTPTGTQTPTMTPITTTT 3809

  Fly  7413 SVPMGSTGGQVTGQTTAPPSEVRTTIRVEESTLPSRSTDRTPPSESPETPTTLPSDFTTRPHSDQ 7477
            :|....|   .||.....|:.:.||..|..          ||.....:||||.|.         .
Human  3810 TVTPTPT---PTGTQAPTPTAITTTTTVTP----------TPTPTGTQTPTTTPI---------T 3852

  Fly  7478 TTESSRDVPTTQPFESSTPRPVTLEIAVPPVTSETTTNVPIGSTGGQVTGQTTATPSEVRTTIGV 7542
            ||.:....||....:|:|..|:|....|.|..:.|.|..|   |...::..||.||:.  |..|.
Human  3853 TTTTVTPTPTPTGTQSTTLTPITTTTTVTPTPTPTGTQTP---TPTPISTTTTVTPTP--TPTGT 3912

  Fly  7543 EESTL-PSRSTDRTTPSESP---ETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFEAS---TPSP 7600
            :..|: |..:|...||:.:|   :||||.|...||......|...|: .|||.|...:   ||:|
Human  3913 QTPTMTPITTTTTVTPTPTPTGTQTPTTTPISTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTP 3976

  Fly  7601 ASLETTVPSVTLETTTNVPIGSTGGQVTGQTTATPSEVRTTIGVE-ESTLPSRSTDRTTPSESP- 7663
            ....|..|:.|       ||.:|       ||.||:.  |..|.: .:|.|..:|...||:.:|
Human  3977 TPTGTQTPTTT-------PISTT-------TTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPT 4025

  Fly  7664 --ETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFEAS---TPRPVTLETAVPSVTSETTTNVPIG 7723
              :||||.|...||......|...|: .||:.|...:   ||.|....|..|:.|..|||
Human  4026 GTQTPTTTPISTTTTVTPTPTPTGTQ-TPTSTPITTTTTVTPTPTPTGTQTPTTTPITTT----- 4084

  Fly  7724 STVTSETTTNVPIGSTGGQVAGQTTAP-PSEVRTTIRVEESTLPSRSADRTTPSESP---ETPTT 7784
               |:.|.|..|.|         |.|| |:.:.||..|             ||:.:|   :||||
Human  4085 ---TTVTPTPTPTG---------TQAPTPTAITTTSTV-------------TPTPTPTGTQTPTT 4124

  Fly  7785 LPSDFTTRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTGGQLTEQS 7849
            .|           .|.:|...||..|....:|:|.::.||    |:.|.|..|.|      |:..
Human  4125 TP-----------ITTTTTVTPTPTPTGTQSPTPTAITTT----TTVTPTPTPTG------TQTP 4168

  Fly  7850 TSSPSEVRTTIRVEESTLPSRSTDRTFPSESPEKPTTLPSDFTTRPHLEQTTESTRDVLTTRPFE 7914
            |.:|....||:                      .||..|:.                      .:
Human  4169 TLTPITTTTTV----------------------TPTPTPTG----------------------TQ 4189

  Fly  7915 TSTPSPVSLETTVPSVTSETSTNVPIGSTGGQVTEQTTAPPSVRTTETIVKSTHPAVSPDTTIPS 7979
            |.||:|:|..|||....:.|.|..|           ||.|.:..||.|      |..:|..|
Human  4190 TPTPTPISTTTTVTPTPTPTGTQTP-----------TTTPITTTTTVT------PTPTPTGT--- 4234

  Fly  7980 EIPATRVPLESTTRLYTDQTIPPGSTDRTTSSERPDESTRLTSEESTETTRPVPTVSPRDALETT 8044
            :.|.| |.:.:||.:....|  |.||..||.:  |..:|...:...|.|....||:.|   :.||
Human  4235 QTPTT-VLITTTTTMTPTPT--PTSTKSTTVT--PITTTTTVTATPTPTGTQTPTMIP---ISTT 4291

  Fly  8045 VTSLITETTKTTSGGTPRGQVTERTTKSVSELTTGRSSDVVTERTMPSNISSTTTVFNNSEPVSD 8109
            .|  :|.|...|:|.|  |..|..:|..::||||   |:...|.:.|....||::....|..:..
Human  4292 TT--VTPTPTPTTGST--GPPTHTSTAPIAELTT---SNPPPESSTPQTSRSTSSPLTESTTLLS 4349

  Fly  8110 NLPTTISITVTDSPTTVPVPTCKTDYDCLDEQTCIGGQCISPCEYFTNLCTVQNLTICRTLNHTT 8174
            .||..|.:|.|..|:|...||           |..||..:||
Human  4350 TLPPAIEMTSTAPPSTPTAPT-----------TTSGGHTLSP----------------------- 4380

  Fly  8175 KCYCDTDDDVNRPDCSMKAEIGCASSDECPSQQACINALCVDPCTFNNPCSRNEDCRVFNHQPLC 8239
                                                                             
Human  4381 ----------------------------------------------------------------- 4380

  Fly  8240 SAEHGRTPGCEHCPPGANCDPTTGACIKANVTITTITTKNSTSTKIPTKPRTTANPNTGVKTTPT 8304
                  .|.....|||.   ||.|            ||..|:|...|:..:||    |....|||
Human  4381 ------PPSTTTSPPGT---PTRG------------TTTGSSSAPTPSTVQTT----TTSAWTPT 4420

  Fly  8305 TTRVTTRNTTTTTTTTTTSSTSTESSTITSATNQTSKNQKPDTE---STTSHT--------DATR 8358
            .|.::|.:...||......|    |..|....|.|  ...|..|   .|...|        ..|.
Human  4421 PTPLSTPSIIRTTGLRPYPS----SVLICCVLNDT--YYAPGEEVYNGTYGDTCYFVNCSLSCTL 4479

  Fly  8359 RYRDGENNITDTPTPRPTIQTTTLRGEGVMGDSQRRSTTTPKMKTTRLDTSNEVPDTTSPWPIEL 8423
            .:.:.....|.:|||.|:                 :||.||..           |.:|...|
Human  4480 EFYNWSCPSTPSPTPTPS-----------------KSTPTPSK-----------PSSTPSKP--- 4513

  Fly  8424 PTTEGTTTEVYNTMFAPVVNTTDTSLINPCTVDTNCAPNEHCKLGHCRKKEPPGSPKTPEPCQSN 8488
              |.||                                            :||..|....|.|.|
Human  4514 --TPGT--------------------------------------------KPPECPDFDPPRQEN 4532

  Fly  8489 ND---CIESEACYMGLCQ--DPCEFAKICAATAKCTAKSHRPVCTCPQGHEGNPMVKCVTTQTSI 8548
            ..   |    .|:|..|:  :..|..|:     :|...   |:.||..|.:
Human  4533 ETWWLC----DCFMATCKYNNTVEIVKV-----ECEPP---PMPTCSNGLQ-------------- 4571

  Fly  8549 ECTDDSDCGVTEACINQLCQHPCDVHDP--CATNAVCINSNHAADCSCA----------DG---- 8597
                                 |..|.||  |..:..|       ||.|.          ||
Human  4572 ---------------------PVRVEDPDGCCWHWEC-------DCYCTGWGDPHYVTFDGLYYS 4608

  Fly  8598 FQGNGFVGCQPARSHVCQY--NEDCPPTKLCDRL-----NRRCINPCQEDSCGENAECIPVNHGT 8655
            :|||            |.|  .|:..|:  .|..     |..| :|..:.||   ...:.|.|.|
Human  4609 YQGN------------CTYVLVEEISPS--VDNFGVYIDNYHC-DPNDKVSC---PRTLIVRHET 4655

  Fly  8656 ECRCLPGFLGNAYVQCLPSQGCRSDSECDSSQACINGKCSS---------PCQCGAYALCDV--- 8708
            :...:      ..|..:|.|          .|..:|.:..:         ..|.|...:.|:
Human  4656 QEVLI------KTVHMMPMQ----------VQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPEL 4704

  Fly  8709 ---VNHRGV---CKCPPGYNGNPKVGCSPPQDPCDPNPCG--LNAL---CELDNGNPICYC---- 8758
               |::.|:   .:.|....||...|           .||  .|..   |.|.:|..:..|
Human  4705 GVLVSYNGLSFSVRLPYHRFGNNTKG-----------QCGTCTNTTSDDCILPSGEIVSNCEAAA 4758

  Fly  8759 PKGLTGNPFKNCIPEGDECTPNPCGPNSGCRRVGGNPVCFCLPEYEGQPPSIPCELPSNPCDPSP 8823
            .:.|..:|.|...|.....|..|.....|    ||...                  |...|.|||
Human  4759 DQWLVNDPSKPHCPHSSSTTKRPAVTVPG----GGKTT------------------PHKDCTPSP 4801

  Fly  8824 CGPNTQCSVLSNG-FSKCTCL--PNYVESPNTIRGCVEPINPCDPNPCGT----GAICDSSR--- 8878
            .     |.::.:. |::|..|  |.:.........|..|.:..:   |.:    .|:|....
Human  4802 L-----CQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGSSLE---CASLQAYAALCAQQNICL 4858

  Fly  8879 ------HPVCY--CPDNKIGNPFRLC---DKPAVTIELCQPGPCGRNAECYVAGNREECYCRSGY 8932
                  |..|.  ||.::   .::.|   ::|.     |:.....:|....|.|    |:|..|.
Human  4859 DWRNHTHGACLVECPSHR---EYQACGPAEEPT-----CKSSSSQQNNTVLVEG----CFCPEGT 4911

  Fly  8933 VGDAYQGCREPSRTVCDPNPCGPNANCVVAGDGQTACVCPDGLSGDPTSVIGCHGYECQVDADCP 8997
            :..|      |...|| ...||              ||.||.:..:    .|.|     .:.||.
Human  4912 MNYA------PGFDVC-VKTCG--------------CVGPDNVPRE----FGEH-----FEFDCK 4946

  Fly  8998 NSKACM----GYRCYDPCPGACGQG--AHCQVE-------EHHP--------VCSCNSGLTGNPG 9041
            |. .|:    |..|.   |..|.|.  .|| ||       |.:|        ||.||:.|
Human  4947 NC-VCLEGGSGIICQ---PKRCSQKPVTHC-VEDGTYLATEVNPADTCCNITVCKCNTSL----- 5001

  Fly  9042 IRCYALDHPKKNPCVPSPCGRNSECKLLNNRAVCSCIPGYLGDPQSGC-------QPECDINSDC 9099
              |      |:.|.| .|.|...:.|::..|    |.|.|..:.:..|       ||...:.|.
Human  5002 --C------KEKPSV-CPLGFEVKSKMVPGR----CCPFYWCESKGVCVHGNAEYQPGSPVYSS- 5052

  Fly  9100 GDTLSCINHKCVDPCAGAICGINAICNVRQHTPVCLCLDGFVGDAFLQCVPIGILKNVSRDPCAP 9164
                     ||.|                     |:|.|....:..|..:           .|..
Human  5053 ---------KCQD---------------------CVCTDKVDNNTLLNVI-----------ACTH 5076

  Fly  9165 SPCGPHDVCSVYGDGVALCDPCFGPNAQQNPRCRPECVGNSDCPFDRACLGQRCLDPCPGSCGRN 9229
            .||.            ..|.|.|  ...:.|   .||     |   :.|....|:...|
Human  5077 VPCN------------TSCSPGF--ELMEAP---GEC-----C---KKCEQTHCIIKRP------ 5110

  Fly  9230 AICNVYEHNPVCACPTGLFGNPYEQCTTKSVVETPPQPSCAKLH-----CGANAECKRQHSGLAC 9289
                  ::..|...|.....:|...||..         ||.|:|     ..:|..|....   |.
Human  5111 ------DNQHVILKPGDFKSDPKNNCTFF---------SCVKIHNQLISSVSNITCPNFD---AS 5157

  Fly  9290 VCRKGYFGDPHIGCRPECVLNSD----CP--------AEKACLNSKCVEACTGVCGV----NAVC 9338
            :|..|.......||...|...::    |.        :...|..:..:..|:|.||.    :|..
Human  5158 ICIPGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYSAKA 5222

  Fly  9339 RVVNHAPVCICAEGYSGDASIACNPFYLPPPERPHPCEPSPCGPNSRCKATPDGYAACSCLPNFK 9403
            :.::|                                                   :|||....|
Human  5223 QALDH---------------------------------------------------SCSCCKEEK 5236

  Fly  9404 GAPPVCQPECVVSSECAPNQACLNQRCTDPCPGICGGGARCEVLNHNPICSCEANFEGDP 9463
                ..|.|.|:|                 ||   .||:......|...|.|:....|.|
Human  5237 ----TSQREVVLS-----------------CP---NGGSLTHTYTHIESCQCQDTVCGLP 5272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpy	NP_001260032.1	EGF_3	137..166	CDD:289699
		EGF_CA	212..247	CDD:238011
		EGF_CA	255..>286	CDD:214542
		EGF_CA	298..331	CDD:238011
		EGF_CA	338..373	CDD:238011
		EGF_CA	413..456	CDD:238011
		EGF_CA	457..490	CDD:238011
		EGF_CA	497..>529	CDD:214542
		EGF_CA	580..>612	CDD:214542
		EGF_3	676..702	CDD:289699
		EGF_CA	1022..1056	CDD:214542
		EGF_CA	2227..2260	CDD:238011
		EGF_CA	2393..>2422	CDD:214542
		DUF4758	4088..4282	CDD:292572	62/205 (30%)
		DUF4696	4127..4678	CDD:292395	175/550 (32%)
		DUF4758	4275..4448	CDD:292572	56/172 (33%)
		DUF4758	4377..4574	CDD:292572	61/196 (31%)
		DUF4758	4581..4754	CDD:292572	53/231 (23%)
		DUF4758	4683..4847	CDD:292572	48/222 (22%)
		DUF4758	4785..4964	CDD:292572	46/181 (25%)
		DUF4696	4841..5385	CDD:292395	143/560 (26%)
		DUF4758	4887..5098	CDD:292572	56/216 (26%)
		DUF4758	5193..5371	CDD:292572	47/182 (26%)
		DUF4758	5294..5487	CDD:292572	54/200 (27%)
		DUF4758	5445..5650	CDD:292572	56/206 (27%)
		DUF4758	5700..5877	CDD:292572	53/190 (28%)
		DUF4696	5756..6396	CDD:292395	167/656 (25%)
		DUF4758	5802..5979	CDD:292572	45/179 (25%)
		DUF4758	5964..6171	CDD:292572	50/206 (24%)
		DUF4758	6181..6360	CDD:292572	44/178 (25%)
		DUF4696	6339..6999	CDD:292395	171/674 (25%)
		DUF4758	6662..6839	CDD:292572	48/179 (27%)
		DUF4758	6764..6941	CDD:292572	43/179 (24%)
		DUF4758	6866..7045	CDD:292572	51/181 (28%)
		DUF4758	6968..7179	CDD:292572	55/213 (26%)
		DUF4696	7024..7569	CDD:292395	158/563 (28%)
		DUF4758	7172..7383	CDD:292572	63/218 (29%)
		DUF4696	7330..7964	CDD:292395	182/658 (28%)
		DUF4758	7400..7587	CDD:292572	56/191 (29%)
		DUF4758	7538..7707	CDD:292572	57/182 (31%)
		DUF4758	7798..7979	CDD:292572	42/180 (23%)
		DUF4758	7946..8126	CDD:292572	54/179 (30%)
		YppG	18767..>18832	CDD:290883
		Med25_SD1	18795..18955	CDD:288132
		MISS	19026..19258	CDD:292450
		ZP	22576..22811	CDD:214579
		Zona_pellucida	<22714..22810	CDD:278526
MUC2	NP_002448.4	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910