Protein Alignment dpy and rtn1a

DIOPT Version :9

• Sequence 1: NP_001260032.1
• Gene: dpy / 318824
• FlyBaseID: FBgn0053196
• Length: 22949
• Species: Drosophila melanogaster
• Sequence 2: NP_001025138.2
• Gene: rtn1a / 323706
• ZFINID: ZDB-GENE-030131-2426
• Length: 818
• Species: Danio rerio
• Alignment Length: 801
• Identity: 165/801 - (20%)
• Similarity: 267/801 - (33%)
• Gaps: 247/801 - (30%)

  Fly  4614 ETTTNVPIGSTG---GQVTGQTTAPPSEFR----TTIRVEESTLPSRSTD---RTTPSESPETPT 4668
            |...|...||.|   .::.....||..:|.    |.:.:|.::.....:|   :::|.|.....:
Zfish    19 EEEKNGMFGSAGPHFDEMRDDLRAPKQQFHPFEGTGVAMETASTGDSLSDMFMKSSPVEGDLYTS 83

  Fly  4669 ILPSDSTTRTYSDQ----TTESTRDVPTTRPFEASTPSPASLETTVPSVTLETTTNVPIGSTGGQ 4729
            :|.|.|::..::|.    ::|..|          |.|:|             |.|:..||.|.|
Zfish    84 LLSSKSSSNPFNDGASLFSSEGNR----------SPPAP-------------TGTDSGIGMTPG- 124

  Fly  4730 VTEQTTSSPSEVRTTIR-------------------------VEESTLPSRS--ADRTTPSESPE 4767
                   .||:.:||::                         .:....|..|  .|.....:..|
Zfish   125 -------DPSDHQTTLQGSHKSDHYSYMDMGGDLCDFGSMGNAKNKQQPPMSGYGDEEDEEDDDE 182

  Fly  4768 TPTTLPSDFITRPHSEKTTESTRDVPTTRPFEASTPSSASLETTVPSVTLETTTNVPIGSTGGQV 4832
            ....: .||..:.....:.||:.|     ||:.......|     |..:.:|......||.|||.
Zfish   183 DEDDI-QDFKPKIEERGSKESSHD-----PFDLGRYLEKS-----PLGSEDTEVKTSTGSAGGQH 236

  Fly  4833 TEQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTTLPSDFITRPHSEKTTESTRDVPTT 4897
            .......||        :|.....||..|   .|:|::.:.:.....|..|| ..:|..|..|..
Zfish   237 AFPYVEDPS--------DEEMADFRSYRR---METPQSASPVKITVTTESHS-TASEPVRVSPQG 289

  Fly  4898 RPFEASTPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSTD 4962
            ...|..:..|.. :..:|:|||                    |.|         |:.:  :.|:.
Zfish   290 GMSERDSVLSFG-QQGLPTVTL--------------------SEP---------EDDS--AASSA 322

  Fly  4963 RTTPSESPETPTTLPSDFTTRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTLETTTNV 5027
            ..:|:.|| |....|||....|...::..||:|..:.    :|.|:|..:.....|....:....
Zfish   323 NHSPNHSP-TGRESPSDVLFHPAGMKSMSSTQDSSSI----SSHPNPPPIHDIKTSAKPSSPWAQ 382

  Fly  5028 PIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTTLPSDFITRTYSDQTT 5092
            .:..:|.:      |..||:.......:|.|...:: :|.|::...:||:.|  |...:|:..|.
Zfish   383 DLQGSGDE------SGDSEIEQVAEELDSPLHDLTS-KTPPAKGGFSPTSNP--FEPPSYTSATD 438

  Fly  5093 ESTR--DVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTGGQVTGQTTAPPSEFRTTIRV 5155
            :::.  |.|.|....||.|...|                 .||..|  .||::.||  ..:.:|.
Zfish   439 KASNPFDKPQTNKVSASNPFDLS-----------------AGSKMG--FGQSSNPP--LYSLLRE 482

  Fly  5156 E-ESTLPSRSTDRTTPSESPETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFEASTPSPASLETT 5219
            | |:.|.|   |....|.|.|:|                         .|..|.|.|.|.  |.:
Zfish   483 EREAELDS---DLLIESASEESP-------------------------KREQEYSAPKPP--EPS 517

  Fly  5220 VPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTLPSD 5284
            .|.:| :..::.||          ||||.|                    ::|...|...:...:
Zfish   518 SPLIT-DNMSSKPI----------TTSSVS--------------------SSPFTEPRVVSAQKE 551

  Fly  5285 FTTRPHSEQTTESTRDVPATRPFEASTPSPASLETTVPSVTSEATTNVPIGSTGGQVTEQTTSSP 5349
                |..|:..|..:..|..:|    .|.|....:|.|......|:.|    |..:...|.|.|.
Zfish   552 ----PEKEKEKEKEKAAPIEKP----KPQPEDSWSTKPRPAVMGTSTV----TPEKQPSQETESK 604

  Fly  5350 SEVRTTIRVEESTLPSRSTDR 5370
            |         :|::.|.||::
Zfish   605 S---------KSSIVSSSTEK 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpy	NP_001260032.1	EGF_3	137..166	CDD:289699
		EGF_CA	212..247	CDD:238011
		EGF_CA	255..>286	CDD:214542
		EGF_CA	298..331	CDD:238011
		EGF_CA	338..373	CDD:238011
		EGF_CA	413..456	CDD:238011
		EGF_CA	457..490	CDD:238011
		EGF_CA	497..>529	CDD:214542
		EGF_CA	580..>612	CDD:214542
		EGF_3	676..702	CDD:289699
		EGF_CA	1022..1056	CDD:214542
		EGF_CA	2227..2260	CDD:238011
		EGF_CA	2393..>2422	CDD:214542
		DUF4758	4088..4282	CDD:292572
		DUF4696	4127..4678	CDD:292395	16/73 (22%)
		DUF4758	4275..4448	CDD:292572
		DUF4758	4377..4574	CDD:292572
		DUF4758	4581..4754	CDD:292572	32/178 (18%)
		DUF4758	4683..4847	CDD:292572	36/190 (19%)
		DUF4758	4785..4964	CDD:292572	37/178 (21%)
		DUF4696	4841..5385	CDD:292395	113/533 (21%)
		DUF4758	4887..5098	CDD:292572	42/212 (20%)
		DUF4758	5193..5371	CDD:292572	37/178 (21%)
		DUF4758	5294..5487	CDD:292572	18/77 (23%)
		DUF4758	5445..5650	CDD:292572
		DUF4758	5700..5877	CDD:292572
		DUF4696	5756..6396	CDD:292395
		DUF4758	5802..5979	CDD:292572
		DUF4758	5964..6171	CDD:292572
		DUF4758	6181..6360	CDD:292572
		DUF4696	6339..6999	CDD:292395
		DUF4758	6662..6839	CDD:292572
		DUF4758	6764..6941	CDD:292572
		DUF4758	6866..7045	CDD:292572
		DUF4758	6968..7179	CDD:292572
		DUF4696	7024..7569	CDD:292395
		DUF4758	7172..7383	CDD:292572
		DUF4696	7330..7964	CDD:292395
		DUF4758	7400..7587	CDD:292572
		DUF4758	7538..7707	CDD:292572
		DUF4758	7798..7979	CDD:292572
		DUF4758	7946..8126	CDD:292572
		YppG	18767..>18832	CDD:290883
		Med25_SD1	18795..18955	CDD:288132
		MISS	19026..19258	CDD:292450
		ZP	22576..22811	CDD:214579
		Zona_pellucida	<22714..22810	CDD:278526
rtn1a	NP_001025138.2	Reticulon	632..796	CDD:280592

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910