DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpy and SPBC16E9.02c

DIOPT Version :9

Sequence 1:	NP_001260032.1	Gene:	dpy / 318824	FlyBaseID:	FBgn0053196	Length:	22949	Species:	Drosophila melanogaster
Sequence 2:	NP_595784.1	Gene:	SPBC16E9.02c / 2539809	PomBaseID:	SPBC16E9.02c	Length:	569	Species:	Schizosaccharomyces pombe

Alignment Length:	516	Identity:	110/516 - (21%)
Similarity:	181/516 - (35%)	Gaps:	114/516 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  7684 ESTRDVPTTRPFEASTPRPVTLETAVPSVTSETTTNVPIGSTVTSETTTNVPIGSTGGQVAGQ-- 7746
            :|...:|...|:.|...| .||:.|.|:........|...|....|...|..:|.:..|||.:
pombe     5 QSNPRLPRRPPYMAEKAR-ATLKEAFPNTDDAIIRAVLAASGYKLEPAFNALLGLSDPQVAEEME 68

  Fly  7747 ---------TTAPPSEVRTTIRVEESTLPSRSADRTTPSESPETPTTLPSDFTTRPHSEQTTEST 7802
                     |.|....|:.  ::||....:|.......|..||             ...:|....
pombe    69 QAETSYAYDTAAHDDPVQR--QLEEDERCARELANRYNSHRPE-------------RRRKTNNDR 118

  Fly  7803 RDVP----TTRPFEASTPSPASLETTVPSV--------------TSETTTNVPIGSTGGQL--TE 7847
            |:.|    |.:|.:......:..|..:|.:              :.|...|:.....|.:.  .:
pombe   119 RNYPPQNRTAKPNDNDGDDYSFFEDDLPVIKDTFMRGFQSFKQRSMEWVENIASKFDGEEEDDDD 183

  Fly  7848 QSTSSPSEVRTTIRVEESTLPSRSTDRTFPSESPEKPTTLPSDFTTRPHLEQTT---ESTRDVLT 7909
            :..|:||::..:        |.|||..|..|...|:|.:||....:||....|.   ||...:|.
pombe   184 EKYSAPSKIYPS--------PRRSTAATLESAYEERPPSLPRRKPSRPGTAITLPPYESDPHMLN 240

  Fly  7910 TRPFE----TSTPSPV----SLETTVPSVTSETSTNVPIGSTGGQVTEQTTAPPSVRTTETIVKS 7966
            .:.||    .|:.||:    ||.:...||.|.:|.....|.:            .:..:...::.
pombe   241 EKDFERLRLESSSSPMMRRSSLNSNRRSVESSSSAAFVEGQS------------FILDSNGAIEV 293

  Fly  7967 THPAVSPDTTIPSEIPATRVPLEST----TRLYTDQTIPPGSTDRTTSSERPDESTR-------L 8020
            .:.|.:.|.:          .|||.    ..:..|.:.|..||......::||||.:       .
pombe   294 ANSAFALDDS----------DLESAYNEELEMKKDTSKPTASTKEVVVEKKPDESRKQAARTLET 348

  Fly  8021 TSEE---STETTRPVPTVSPRDALETTVTSLITETTKTTSGGTPRGQVTERTTKSVSELTTGRSS 8082
            .|||   |:.....|.|..|:|:     ||:..|.|:|......:|......|..:||.|..:::
pombe   349 VSEEQMGSSNAKSKVLTSEPKDS-----TSVEAEKTETDEPAVGKGASDVSDTAEISEKTEAKNA 408

  Fly  8083 DVVTERTMPSNISSTTTVFNNSEPVSDNLPTTISITVTDSPTTVP-VPTCKTDYDCLDEQT 8142
            |      ..:|:...:.|....|...:|...::...|.:..|.:. ..|.||:.|...::|
pombe   409 D------SEANLEEKSDVGEEKESKDENNKASLHKDVEEKDTKITNEDTGKTETDVKAKET 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpy	NP_001260032.1	EGF_3	137..166	CDD:289699
		EGF_CA	212..247	CDD:238011
		EGF_CA	255..>286	CDD:214542
		EGF_CA	298..331	CDD:238011
		EGF_CA	338..373	CDD:238011
		EGF_CA	413..456	CDD:238011
		EGF_CA	457..490	CDD:238011
		EGF_CA	497..>529	CDD:214542
		EGF_CA	580..>612	CDD:214542
		EGF_3	676..702	CDD:289699
		EGF_CA	1022..1056	CDD:214542
		EGF_CA	2227..2260	CDD:238011
		EGF_CA	2393..>2422	CDD:214542
		DUF4758	4088..4282	CDD:292572
		DUF4696	4127..4678	CDD:292395
		DUF4758	4275..4448	CDD:292572
		DUF4758	4377..4574	CDD:292572
		DUF4758	4581..4754	CDD:292572
		DUF4758	4683..4847	CDD:292572
		DUF4758	4785..4964	CDD:292572
		DUF4696	4841..5385	CDD:292395
		DUF4758	4887..5098	CDD:292572
		DUF4758	5193..5371	CDD:292572
		DUF4758	5294..5487	CDD:292572
		DUF4758	5445..5650	CDD:292572
		DUF4758	5700..5877	CDD:292572
		DUF4696	5756..6396	CDD:292395
		DUF4758	5802..5979	CDD:292572
		DUF4758	5964..6171	CDD:292572
		DUF4758	6181..6360	CDD:292572
		DUF4696	6339..6999	CDD:292395
		DUF4758	6662..6839	CDD:292572
		DUF4758	6764..6941	CDD:292572
		DUF4758	6866..7045	CDD:292572
		DUF4758	6968..7179	CDD:292572
		DUF4696	7024..7569	CDD:292395
		DUF4758	7172..7383	CDD:292572
		DUF4696	7330..7964	CDD:292395	67/321 (21%)
		DUF4758	7400..7587	CDD:292572
		DUF4758	7538..7707	CDD:292572	7/22 (32%)
		DUF4758	7798..7979	CDD:292572	43/211 (20%)
		DUF4758	7946..8126	CDD:292572	38/193 (20%)
		YppG	18767..>18832	CDD:290883
		Med25_SD1	18795..18955	CDD:288132
		MISS	19026..19258	CDD:292450
		ZP	22576..22811	CDD:214579
		Zona_pellucida	<22714..22810	CDD:278526
SPBC16E9.02c	NP_595784.1	CUE_Cue5p_like	17..61	CDD:270555	11/44 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910