DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpy and FBN1

DIOPT Version :9

Sequence 1:	NP_001260032.1	Gene:	dpy / 318824	FlyBaseID:	FBgn0053196	Length:	22949	Species:	Drosophila melanogaster
Sequence 2:	NP_000129.3	Gene:	FBN1 / 2200	HGNCID:	3603	Length:	2871	Species:	Homo sapiens

Alignment Length:	3268	Identity:	794/3268 - (24%)
Similarity:	1063/3268 - (32%)	Gaps:	1216/3268 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 CTND---CDKD--GTKC----THGACLNG-------VCHCNDGYGGCNCVDKDENECKQRPC-DV 140
            |::|   |.|.  ||.|    ....||||       .|.|..|:.|..|    |.:.:..|| .|
Human   129 CSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQC----ERDYRTGPCFTV 189

  Fly   141 FAH-----------CTNTLGSFT-----------CTCFPGYRGNGF-------HCEDIDECQDPA 176
            .::           ||.||...|           |...|.....||       .|:|:||||  |
Human   190 ISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQ--A 252

  Fly   177 IAARCVENAECCNLPAHFLCKCKDGYE-GDGEVLCTDVDECRNPENCGPNALCTNTPGNYTCSCP 240
            |...| :...|.|....|.|||..|:: .:....|.|:|||...........||||..:|.|.||
Human   253 IPGLC-QGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCP 316

  Fly   241 DGYVGNNP-------YREG------------------------CQDVDECSYPNV---------- 264
            .|:. .:|       .|.|                        |.|...|..|.|
Human   317 PGFY-TSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIR 380

  Fly   265 --------CG------------------------------PGA---------------------- 269
                    |.                              ||.
Human   381 ATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVL 445

  Fly   270 -------------ICTN-----LEGSYRCDCPPGYDGDGRSESGCVDQDECARTPCGRNADCLNT 316
                         :|.|     ..|||||:|..|:..|.|.|  |:|.|||.:.||. ..:|:|.
Human   446 PVNVTDYCQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGE--CIDVDECEKNPCA-GGECINN 507

  Fly   317 DGSFRCLCPDGYSGD-PMNGCEDVDECATNNPCGLGAECVNLGGSFQCRCPSGFVLEHDPHADQL 380
            .||:.|.|..||... ....|.|:|||..|........|:|..|||.|.|.:||.:..|
Human   508 QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRD------ 566

  Fly   381 PQPLNTQQLGYGPGATDIAPYQRTSGAGLACLDIDECNQPDGVAKCGTNAKCINFPGSYRCLCPS 445
                                       |..|.|:|||:    :.....|..|||..||::|:|..
Human   567 ---------------------------GKNCEDMDECS----IRNMCLNGMCINEDGSFKCICKP 600

  Fly   446 GFQ----GQGYLHCENINECQDNPCGENAICTDTVGSFVCTCKPD-------------------Y 487
            |||    |:   :|::||||:......|..|.:|.||:.|.|.|.                   |
Human   601 GFQLASDGR---YCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCY 662

  Fly   488 TG-------DPFRGCVDIDECT------ALDKPCGQHAVCENTVPGYNCKCPQGYDGKPDPKVAC 539
            .|       .|..|.|...||.      |..:|| |....:|:.. |...|..|      |.:..
Human   663 GGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPC-QPCPAQNSAE-YQALCSSG------PGMTS 719

  Fly   540 EQVDVNILCSSNFDCTNNAECIEN-----QCFCLDGFE--PIGSSCVDIDECRTHAEVCGPHAQC 597
            ...|:| .|:.:.|...|..| ||     :|.|..|:|  ..|.:||||:||..::.:| .:.||
Human   720 AGSDIN-ECALDPDICPNGIC-ENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLC-DNGQC 781

  Fly   598 LNTPGSYGCECEAGYVGSPPRMACK--QPCEDVRCGAHAYCKPDQNEAYCVCEDGWTYNPS---- 656
            .|||||:.|.|..|::..|....|:  ..||...| .:..||.......|.|....|.:|:
Human   782 RNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPC-INGVCKNSPGSFICECSSESTLDPTKTIC 845

  Fly   657 -----------------------------------------------DVAAG----------CVD 664
                                                           |...|          |.|
Human   846 IETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCED 910

  Fly   665 IDECDVMHGPFGSCGQNATCTNSAGGFTCACPPGFSGDPHSK-CVDV-----------DEC---- 713
            ||||:|..   |.| :|..|.|:.|.|.|.||.|.:.|...: |:|:           :||
Human   911 IDECEVFP---GVC-KNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPI 971

  Fly   714 ----RTGASKCGAGA--------ECV--NVPGGGYTC-RCPG---NTIADPDPSVR----CVPIV 756
                |..|..|..||        ||.  |.|.....| |.||   ..|.:..|..:    |..|.
Human   972 AGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIP 1036

  Fly   757 SCSANEDCPGNSICDATKRCLC--------PEPNIG--NDCRHPCEALNCGAHAQCMLANGQAQC 811
            |...:..| .|:|  .:.:|.|        .|.|..  ::||...:.  || ..||:...|..:|
Human  1037 SLCTHGKC-RNTI--GSFKCRCDSGFALDSEERNCTDIDECRISPDL--CG-RGQCVNTPGDFEC 1095

  Fly   812 LCAPGYTGNSALAGGCNDIDECRANP-CAEKAICSNTAGGYLCQCPGGSSGDPYREGCITSKTVG 875
            .|..||.....:...|.|||||:.:| .....:|.||.|.|.|:||.|....|....||......
Human  1096 KCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECE 1160

  Fly   876 CSDANPCATGETCVQDSYTGNSVCICRQGYERNSENGQCQDVDECSVQRGKPACGLNALCKNLPG 940
            .| |:.|..|. ||  :..|...|.|..||....:...|.|:||||:..|    |....|.|..|
Human  1161 LS-AHLCPNGR-CV--NLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNG----GCETFCTNSEG 1217

  Fly   941 SYECRCPQGHNGNPFIMCEICNTPECQCQSPYKLVGN--SCV-LSGCSSGQACPSGAECISIAGG 1002
            ||||.|..|                      :.|:.:  ||. :..|........|.:|.:|.|
Human  1218 SYECSCQPG----------------------FALMPDQRSCTDIDECEDNPNICDGGQCTNIPG- 1259

  Fly  1003 VSY-CACPKGYQTQPD-GSCVDVDECEERGAQLCAFGAQCVNKPGSYSCHCPEGYQGDAYNGLCA 1065
             .| |.|..|:....| .:||||:|| :....:|..|. |.|..||:.|||..||.|
Human  1260 -EYRCLCYDGFMASEDMKTCVDVNEC-DLNPNICLSGT-CENTKGSFICHCDMGYSG-------- 1313

  Fly  1066 LAQRKCAADRECAANEKCIQPGECVCPPPYFLDPQDNNKCKSPCERFPCGINAKCT-PSDPPQCM 1129
                               :.|:..|        .|.|:|:.....  ||.:|.|| .:...:|.
Human  1314 -------------------KKGKTGC--------TDINECEIGAHN--CGKHAVCTNTAGSFKCS 1349

  Fly  1130 CEAGFKGDPLLGCTDEDECS---HLPCAYGAYCVNKKGGYQCVCPKDYTGDPYKSGCIFESGTPK 1191
            |..|:.||. :.|||.||||   |: |:..|.|.|..|.|:|:|.:.||||.:
Human  1350 CSPGWIGDG-IKCTDLDECSNGTHM-CSQHADCKNTMGSYRCLCKEGYTGDGF------------ 1400

  Fly  1192 SKCLSNDDCASNLACLEGSCVSPCSSLLCGSNAYCETEQHAGWCRCRVGYVKNGDGDCVSQCQDV 1256
             .|...|:|:.||.             ||| |..|........|.|.:|:|.:.||   ..|:|:
Human  1401 -TCTDLDECSENLN-------------LCG-NGQCLNAPGGYRCECDMGFVPSADG---KACEDI 1447

  Fly  1257 ICGDGALCIPTSEGPTCKCPQGQLGNPFPGGSCSTDQCSAARPCGERQICINGRCKE-----RCE 1316
                                               |:||..      .||:.|.|..     |||
Human  1448 -----------------------------------DECSLP------NICVFGTCHNLPGLFRCE 1471

  Fly  1317 GVVCGIGATCDRNNGKCI----C-EP------NFVGNPDLI---CMPPIEQAKCSPGC------- 1360
               |.||...||:.|.|.    | :|      |.|..|...   |.|..|......||
Human  1472 ---CEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGN 1533

  Fly  1361 --------GENAH--C--EYGLGQSR--CACNPG-TFGNPYEGCGAQSKNVCQPNSCGPNAECRA 1410
                    |:|..  |  |.|:|.|:  |.|:.| .:|.|.|.|.|.:.
Human  1534 CYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNT---------------- 1582

  Fly  1411 VGNHISCLCP--QGFSGNPY-IGCQDVDECANKPCGL--NAACLNRAGGFECLCLSGHAGNPYSS 1470
              :....|||  :||..||. :..:|:|||...| ||  ...|:|..|.|:|.|.:|:..|.
Human  1583 --SEYKILCPGGEGFRPNPITVILEDIDECQELP-GLCQGGKCINTFGSFQCRCPTGYYLNE--- 1641

  Fly  1471 CQPIESKFCQDANKCQCNERVECPEGYSCQKGQCKNLCSQASCGPRAICDAGN--CICPMGYIGD 1533
                :::.|.|.|:|      |.|.  .|..|.|.|             ..||  ||||..|:
Human  1642 ----DTRVCDDVNEC------ETPG--ICGPGTCYN-------------TVGNYTCICPPDYM-- 1679

  Fly  1534 PHDQVHGCSIRGQCGNDADCLHSEICFQLGKGLRKCVDACSKIQCGPNALCVSE----DHRSSCI 1594
               ||:|       ||:        |..:.:.|      |.:.....|..|..|    ..:..|.
Human  1680 ---QVNG-------GNN--------CMDMRRSL------CYRNYYADNQTCDGELLFNMTKKMCC 1720

  Fly  1595 CSDGFFGNPSNLQVGCQPERTVPEEEDKCKSDQDCSRGY------GCQASVNGIKECINLCSNVV 1653
            ||.. .|...|......|..:..|....|.|.:.   |:      |....::..:|...:|.|.|
Human  1721 CSYN-IGRAWNKPCEQCPIPSTDEFATLCGSQRP---GFVIDIYTGLPVDIDECREIPGVCENGV 1781

  Fly  1654 CGPNELCKINPAGHAICNCAESYVWNPVVSSCEKPSLPDCTSDANCPDASACRPDVLGVLKCVAI 1718
            |       ||..|...|.|...:.:|..:..||  .:.:|   .|.|
Human  1782 C-------INMVGSFRCECPVGFFYNDKLLVCE--DIDEC---QNGP------------------ 1816

  Fly  1719 CDAFTCPANSVCVARQHQGRCDCLNGF----VGNPNDRNGCQPAQKHHCRNHAECQE---SEACI 1776
                .|..|:.|:......||||..|:    .|..||||.||.. .:.| :|.:|.:   |..|:
Human  1817 ----VCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEI-PNIC-SHGQCIDTVGSFYCL 1875

  Fly  1777 -------KDESTQTLGCRPACDTVKCGPRAVCVTNNHQAQCQCPPGPFAGDPYDPFNGCQSVPCV 1834
                   .|:.|..|... .|:...|| ...|........|:|..|                 .:
Human  1876 CHTGFKTNDDQTMCLDIN-ECERDACG-NGTCRNTIGSFNCRCNHG-----------------FI 1921

  Fly  1835 YNHDCPPSQMCNRMTHTCFDVCDEESCGD-----NAICLAEDHRAVCQCPPGFKGDPLPEVA--- 1891
            .:|:           :.|.|| ||.:.|:     |..|:.......|||..|:      |||
Human  1922 LSHN-----------NDCIDV-DECASGNGNLCRNGQCINTVGSFQCQCNEGY------EVAPDG 1968

  Fly  1892 --CT-------KQGGCAAGTCHPSAICEVTPEGPV-CKCPPLFVGDAKSGGCRPDGQCPNGDADC 1946
              |.       :...||.|||.       ..:|.. |.|||        |....:.:|.:.|...
Human  1969 RTCVDINECLLEPRKCAPGTCQ-------NLDGSYRCICPP--------GYSLQNEKCEDIDECV 2018

  Fly  1947 PANTICAGGVCQNPCDNACGSNAECKVINRKPVCSCPLRFQPISDTAKDGCARTISKCLTDVDCG 2011
            ....|||.|.|.|       :....|       |.||..|. :|.:.:        :|   .|..
Human  2019 EEPEICALGTCSN-------TEGSFK-------CLCPEGFS-LSSSGR--------RC---QDLR 2057

  Fly  2012 GALCY----NGQCRIACRNSQDCSDGESC--LK-----NVCVVACLDHSQ-----CASGLACVEG 2060
            .:.||    .|:|  :...|::.|..|.|  ||     :.|.:...:..:     |..|...:.|
Human  2058 MSYCYAKFEGGKC--SSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVG 2120

  Fly  2061 HCTIGCRSNKECKQDQSCIENKCLNPCQSANSCGPNALCSIDQHHSQCSCPEGFEGNPTPEQGCV 2125
                         .|.|.::   ::.|:..:.|          .|.||...:|       ...|
Human  2121 -------------PDDSAVD---MDECKEPDVC----------KHGQCINTDG-------SYRC- 2151

  Fly  2126 RVPAPCLASNQCPSGHMCIGNQCNLPCTKTASCAVGERCYQQVCRKVCYTSNNCLAGEICNSDRT 2190
                      :||.|::..||:    |..|..|:||..|....|:       |.:.|..|..:..
Human  2152 ----------ECPFGYILAGNE----CVDTDECSVGNPCGNGTCK-------NVIGGFECTCEEG 2195

  Fly  2191 CQPG----CDSDADCPPTEL-----CL----TGKCKCATGFI--GTPFGCSDIDECTE--QPC-H 2237
            .:||    |:...:|....|     |:    :.:|||..|::  .....|.|.|||.|  ..| .
Human  2196 FEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTE 2260

  Fly  2238 ASARCENLPGTYRCVCPEGTVGDGYSQ----PGCSQPRQCH-KPDDCANNLACIHGKCTDPCLHT 2297
            ....|:||.|||.|:|     |.||.:    .||....:|. ||..|.|      |:|.:
Human  2261 KQMECKNLIGTYMCIC-----GPGYQRRPDGEGCVDENECQTKPGICEN------GRCLN----- 2309

  Fly  2298 VCGINANCQSEGHEALCSCPAGFLGDPN-----DTGVG-CF-------------------KVECI 2337
                     :.| ...|.|..||...||     |...| ||                   |.||.
Human  2310 ---------TRG-SYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECC 2364

  Fly  2338 DHVDCAGDRA----CD------------------------AETNRCIKPCDLTSCGKGNCQVRDH 2374
                |.|.|.    |:                        |:.:.|....|:  |..|.| |.|.
Human  2365 ----CDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDV--CRNGEC-VNDR 2422

  Fly  2375 KA-TCACYEGY--QLVNDVCEDINECLSQPCHSTAFCNNLPGSYSCQCPEGLIGDPLQAGCRDPN 2436
            .: .|.|..||  .:....|.|:|||...|......|.|..|||.|.||:|.|.......|:|.:
Human  2423 GSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLD 2487

  Fly  2437 ECLSDADCPASASCQNSRCRSPCERQNACGLNANCQAQAHQAI----CTCPLNSRGDPTIECVHI 2497
            ||.:                    :|:      |||......|    |.||      |.....|.
Human  2488 ECAT--------------------KQH------NCQFLCVNTIGGFTCKCP------PGFTQHHT 2520

  Fly  2498 ECADNDDCSGEKACLDSKCIDPCSLPNACGALARCSVQNHIG--VCSCEAG----STGDAKLGCV 2556
            .|.||::|:.:              .|.||:...|  ||..|  .|.|:.|    .||.:
Human  2521 SCIDNNECTSD--------------INLCGSKGIC--QNTPGSFTCECQRGFSLDQTGSS----- 2564

  Fly  2557 QLQYCQQDGQCAQGSICSHGICSPLCSTNRDCISEQLCLQGVCQGTCKSNSSCPQ--FQFCSNNI 2619
                |:...:|.....|.|| |..:....|                |    ||||  .|....|.
Human  2565 ----CEDVDECEGNHRCQHG-CQNIIGGYR----------------C----SCPQGYLQHYQWNQ 2604

  Fly  2620 CTKELECRSDSECGEDETCLSDAYGRAKCESVCLGRAACGRNAECVARSHAPDCLCKEGF-FGDA 2683
            |..|.||.|...||                           .|.|.....:..|:|..|| :...
Human  2605 CVDENECLSAHICG---------------------------GASCHNTLGSYKCMCPAGFQYEQF 2642

  Fly  2684 KSGCRKI-ECTSDDDCSNDKSCDNHMCKIACLIGQPCGENALCTTEHHQQVCHCQPGFSGDPRVR 2747
            ..||:.| ||.|
Human  2643 SGGCQDINECGS----------------------------------------------------- 2654

  Fly  2748 CDVIDFCRDAPCGPGARCRNARGSYKCTCPPGL--VGDPYNEGCRSSVECETNEDCPPHA----- 2805
                   ..|||..|  |.|..|.|.|.||||.  :|..:   |.|.:........||.:
Human  2655 -------AQAPCSYG--CSNTEGGYLCGCPPGYFRIGQGH---CVSGMGMGRGNPEPPVSGEMDD 2707

  Fly  2806 ------AC--TKTNGVAK 2815
                  ||  .|.||..|
Human  2708 NSLSPEACYECKINGYPK 2725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpy	NP_001260032.1	EGF_3	137..166	CDD:289699	12/58 (21%)
		EGF_CA	212..247	CDD:238011	13/34 (38%)
		EGF_CA	255..>286	CDD:214542	15/118 (13%)
		EGF_CA	298..331	CDD:238011	14/32 (44%)
		EGF_CA	338..373	CDD:238011	14/34 (41%)
		EGF_CA	413..456	CDD:238011	16/46 (35%)
		EGF_CA	457..490	CDD:238011	14/58 (24%)
		EGF_CA	497..>529	CDD:214542	9/37 (24%)
		EGF_CA	580..>612	CDD:214542	14/31 (45%)
		EGF_3	676..702	CDD:289699	11/25 (44%)
		EGF_CA	1022..1056	CDD:214542	14/33 (42%)
		EGF_CA	2227..2260	CDD:238011	14/35 (40%)
		EGF_CA	2393..>2422	CDD:214542	13/28 (46%)
		DUF4758	4088..4282	CDD:292572
		DUF4696	4127..4678	CDD:292395
		DUF4758	4275..4448	CDD:292572
		DUF4758	4377..4574	CDD:292572
		DUF4758	4581..4754	CDD:292572
		DUF4758	4683..4847	CDD:292572
		DUF4758	4785..4964	CDD:292572
		DUF4696	4841..5385	CDD:292395
		DUF4758	4887..5098	CDD:292572
		DUF4758	5193..5371	CDD:292572
		DUF4758	5294..5487	CDD:292572
		DUF4758	5445..5650	CDD:292572
		DUF4758	5700..5877	CDD:292572
		DUF4696	5756..6396	CDD:292395
		DUF4758	5802..5979	CDD:292572
		DUF4758	5964..6171	CDD:292572
		DUF4758	6181..6360	CDD:292572
		DUF4696	6339..6999	CDD:292395
		DUF4758	6662..6839	CDD:292572
		DUF4758	6764..6941	CDD:292572
		DUF4758	6866..7045	CDD:292572
		DUF4758	6968..7179	CDD:292572
		DUF4696	7024..7569	CDD:292395
		DUF4758	7172..7383	CDD:292572
		DUF4696	7330..7964	CDD:292395
		DUF4758	7400..7587	CDD:292572
		DUF4758	7538..7707	CDD:292572
		DUF4758	7798..7979	CDD:292572
		DUF4758	7946..8126	CDD:292572
		YppG	18767..>18832	CDD:290883
		Med25_SD1	18795..18955	CDD:288132
		MISS	19026..19258	CDD:292450
		ZP	22576..22811	CDD:214579
		Zona_pellucida	<22714..22810	CDD:278526
FBN1	NP_000129.3	TB	195..>228	CDD:334208	6/32 (19%)
		EGF_CA	246..>276	CDD:214542	14/32 (44%)
		EGF_CA	288..329	CDD:214542	14/41 (34%)
		TB	345..389	CDD:334208	5/43 (12%)
		EGF_CA	490..521	CDD:214542	14/31 (45%)
		EGF_CA	530..571	CDD:214542	16/73 (22%)
		EGF_CA	572..612	CDD:214542	16/46 (35%)
		EGF_CA	613..646	CDD:214542	12/32 (38%)
		TB	670..711	CDD:334208	11/42 (26%)
		EGF_CA	723..763	CDD:311536	13/41 (32%)
		EGF_CA	765..806	CDD:238011	16/41 (39%)
		TB	862..>894	CDD:334208	0/31 (0%)
		TB	967..1009	CDD:334208	10/41 (24%)
		EGF_CA	1070..1104	CDD:214542	11/36 (31%)
		EGF_CA	1113..1149	CDD:214542	15/35 (43%)
		EGF_CA	1155..1188	CDD:214542	11/36 (31%)
		vWFA	<1194..1235	CDD:350880	18/66 (27%)
		EGF_3	1326..1361	CDD:315598	11/37 (30%)
		EGF_3	1367..1402	CDD:315598	15/48 (31%)
		cEGF	1426..1449	CDD:338440	8/60 (13%)
		EGF_CA	1446..1486	CDD:214542	17/83 (20%)
		EGF_CA	1487..1518	CDD:214542	7/30 (23%)
		TB	1549..1590	CDD:334208	14/58 (24%)
		EGF_CA	1606..1638	CDD:214542	14/32 (44%)
		EGF_CA	1648..1687	CDD:214542	21/79 (27%)
		TB	1706..1749	CDD:334208	9/43 (21%)
		EGF_CA	1766..>1797	CDD:214542	10/37 (27%)
		EGF_CA	1808..1840	CDD:214542	11/56 (20%)
		vWFA	<1847..1886	CDD:350880	12/40 (30%)
		EGF_CA	1930..1971	CDD:311536	14/47 (30%)
		EGF_CA	1973..2008	CDD:238011	11/49 (22%)
		EGF_CA	2013..2053	CDD:354843	13/62 (21%)
		TB	2070..2112	CDD:334208	8/43 (19%)
		EGF_CA	2127..2165	CDD:214542	12/72 (17%)
		EGF_CA	2166..2205	CDD:214542	11/45 (24%)
		vWFA	<2289..2328	CDD:350880	14/59 (24%)
		TB	2356..2391	CDD:334208	7/38 (18%)
		vWFA	<2442..2482	CDD:350880	16/39 (41%)
		cEGF	2465..2488	CDD:338440	9/22 (41%)
		EGF_CA	2485..>2516	CDD:354843	12/62 (19%)
		EGF_CA	2524..2566	CDD:214542	15/66 (23%)
		EGF_CA	2567..>2596	CDD:214542	11/49 (22%)
		EGF_CA	2607..2638	CDD:214542	11/57 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	51	1.000	Domainoid score	I11573
eggNOG	1	0.900	-	-		E33208_3BA2W
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D4721at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41397
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820