Protein Alignment dpy and Pros1

DIOPT Version :9

• Sequence 1: NP_001260032.1
• Gene: dpy / 318824
• FlyBaseID: FBgn0053196
• Length: 22949
• Species: Drosophila melanogaster
• Sequence 2: NP_035303.1
• Gene: Pros1 / 19128
• MGIID: 1095733
• Length: 675
• Species: Mus musculus
• Alignment Length: 248
• Identity: 84/248 - (33%)
• Similarity: 116/248 - (46%)
• Gaps: 49/248 - (19%)

  Fly   130 ENECKQRPC------DVFAHCTNT-------LGSFTCTCFPGYRGNGFHC--------EDIDEC- 172
            |.||.:..|      :||.:...|       ||     |...:|...||.        .|:..|
Mouse    55 ERECIEELCNKEEAREVFENNPETDYFYPKYLG-----CLGAFRVGSFHAARQSANAYPDLRSCV 114

  Fly   173 ---QDPAIAARCVENA--ECCNLPAHFLCKCKDGYEGDGEVLCT-DVDECRNPENC--GPNALCT 229
               .|......|.|:.  .|.:..|.|.|.||.|::||   .|. ||:||::|.|.  |.:.:|.
Mouse   115 KAISDQCDPIPCNEDGYLACQDGQAAFTCFCKPGWQGD---RCQYDVNECKDPSNVNGGCSQICD 176

  Fly   230 NTPGNYTCSCPDGYVGNNPYREGCQDVDECSY-PNVCGPGAICTNLEGSYRCDCPPGYDGDGRSE 293
            ||||:|.|||..|: ...|.::.|:|:|||:. |:|||. |:|.|:.|.:.|:||.||..|..|:
Mouse   177 NTPGSYHCSCKRGF-AMLPNKKDCKDLDECALKPSVCGT-AVCKNIPGDFECECPDGYRYDPSSK 239

  Fly   294 SGCVDQDECARTPCGRNADCLNTDGSFRCLCPDGYSG----DPMNGCEDVDEC 342
            | |.|.|||:...|.:.  |:|..|.:.|.| ||..|    .....||.:..|
Mouse   240 S-CKDVDECSENMCAQL--CVNFPGGYSCYC-DGKKGFKLAQDQKSCEGIPVC 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpy	NP_001260032.1	EGF_3	137..166	CDD:289699	9/41 (22%)
		EGF_CA	212..247	CDD:238011	17/36 (47%)
		EGF_CA	255..>286	CDD:214542	15/31 (48%)
		EGF_CA	298..331	CDD:238011	13/36 (36%)
		EGF_CA	338..373	CDD:238011	1/5 (20%)
		EGF_CA	413..456	CDD:238011
		EGF_CA	457..490	CDD:238011
		EGF_CA	497..>529	CDD:214542
		EGF_CA	580..>612	CDD:214542
		EGF_3	676..702	CDD:289699
		EGF_CA	1022..1056	CDD:214542
		EGF_CA	2227..2260	CDD:238011
		EGF_CA	2393..>2422	CDD:214542
		DUF4758	4088..4282	CDD:292572
		DUF4696	4127..4678	CDD:292395
		DUF4758	4275..4448	CDD:292572
		DUF4758	4377..4574	CDD:292572
		DUF4758	4581..4754	CDD:292572
		DUF4758	4683..4847	CDD:292572
		DUF4758	4785..4964	CDD:292572
		DUF4696	4841..5385	CDD:292395
		DUF4758	4887..5098	CDD:292572
		DUF4758	5193..5371	CDD:292572
		DUF4758	5294..5487	CDD:292572
		DUF4758	5445..5650	CDD:292572
		DUF4758	5700..5877	CDD:292572
		DUF4696	5756..6396	CDD:292395
		DUF4758	5802..5979	CDD:292572
		DUF4758	5964..6171	CDD:292572
		DUF4758	6181..6360	CDD:292572
		DUF4696	6339..6999	CDD:292395
		DUF4758	6662..6839	CDD:292572
		DUF4758	6764..6941	CDD:292572
		DUF4758	6866..7045	CDD:292572
		DUF4758	6968..7179	CDD:292572
		DUF4696	7024..7569	CDD:292395
		DUF4758	7172..7383	CDD:292572
		DUF4696	7330..7964	CDD:292395
		DUF4758	7400..7587	CDD:292572
		DUF4758	7538..7707	CDD:292572
		DUF4758	7798..7979	CDD:292572
		DUF4758	7946..8126	CDD:292572
		YppG	18767..>18832	CDD:290883
		Med25_SD1	18795..18955	CDD:288132
		MISS	19026..19258	CDD:292450
		ZP	22576..22811	CDD:214579
		Zona_pellucida	<22714..22810	CDD:278526
Pros1	NP_035303.1	GLA	23..85	CDD:214503	7/29 (24%)
		Thrombin-sensitive	88..116		6/27 (22%)
		Plasmod_Pvs28	134..287	CDD:283826	65/161 (40%)
		FXa_inhibition	165..199	CDD:291342	13/34 (38%)
		EGF_CA	201..241	CDD:284955	20/41 (49%)
		FXa_inhibition	247..282	CDD:291342	10/37 (27%)
		Laminin_G_1	329..459	CDD:278483
		LamG	514..646	CDD:304605

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I11921
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000