DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpy and Notch1

DIOPT Version :9

Sequence 1:NP_001260032.1 Gene:dpy / 318824 FlyBaseID:FBgn0053196 Length:22949 Species:Drosophila melanogaster
Sequence 2:NP_032740.3 Gene:Notch1 / 18128 MGIID:97363 Length:2531 Species:Mus musculus


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpyNP_001260032.1 EGF_3 137..166 CDD:289699
EGF_CA 212..247 CDD:238011
EGF_CA 255..>286 CDD:214542
EGF_CA 298..331 CDD:238011
EGF_CA 338..373 CDD:238011
EGF_CA 413..456 CDD:238011
EGF_CA 457..490 CDD:238011
EGF_CA 497..>529 CDD:214542
EGF_CA 580..>612 CDD:214542
EGF_3 676..702 CDD:289699
EGF_CA 1022..1056 CDD:214542
EGF_CA 2227..2260 CDD:238011
EGF_CA 2393..>2422 CDD:214542
DUF4758 4088..4282 CDD:292572
DUF4696 4127..4678 CDD:292395
DUF4758 4275..4448 CDD:292572
DUF4758 4377..4574 CDD:292572
DUF4758 4581..4754 CDD:292572
DUF4758 4683..4847 CDD:292572
DUF4758 4785..4964 CDD:292572
DUF4696 4841..5385 CDD:292395
DUF4758 4887..5098 CDD:292572
DUF4758 5193..5371 CDD:292572
DUF4758 5294..5487 CDD:292572
DUF4758 5445..5650 CDD:292572
DUF4758 5700..5877 CDD:292572
DUF4696 5756..6396 CDD:292395
DUF4758 5802..5979 CDD:292572
DUF4758 5964..6171 CDD:292572
DUF4758 6181..6360 CDD:292572
DUF4696 6339..6999 CDD:292395
DUF4758 6662..6839 CDD:292572
DUF4758 6764..6941 CDD:292572
DUF4758 6866..7045 CDD:292572
DUF4758 6968..7179 CDD:292572
DUF4696 7024..7569 CDD:292395
DUF4758 7172..7383 CDD:292572
DUF4696 7330..7964 CDD:292395
DUF4758 7400..7587 CDD:292572
DUF4758 7538..7707 CDD:292572
DUF4758 7798..7979 CDD:292572
DUF4758 7946..8126 CDD:292572
YppG 18767..>18832 CDD:290883
Med25_SD1 18795..18955 CDD:288132
MISS 19026..19258 CDD:292450
ZP 22576..22811 CDD:214579
Zona_pellucida <22714..22810 CDD:278526
Notch1NP_032740.3 EGF_CA 142..175 CDD:238011
EGF_CA 178..216 CDD:238011
EGF_CA 257..293 CDD:238011
EGF_CA 295..332 CDD:238011
EGF_CA 335..370 CDD:238011
EGF_CA 412..450 CDD:238011
Interaction with DLL4. /evidence=ECO:0000250|UniProtKB:Q07008 420..421
Interaction with DLL4. /evidence=ECO:0000250|UniProtKB:Q07008 448..452
EGF_CA 452..488 CDD:238011
EGF_CA 490..526 CDD:238011
EGF_CA 528..564 CDD:238011
EGF_CA 566..601 CDD:238011
EGF_CA 603..639 CDD:238011
EGF_CA 641..675 CDD:238011
EGF_CA 678..713 CDD:238011
EGF_CA 717..750 CDD:238011
EGF_CA 755..789 CDD:238011
EGF_CA 791..827 CDD:238011
EGF_CA 869..905 CDD:238011
EGF_CA 907..943 CDD:238011
EGF_CA 945..981 CDD:238011
EGF_CA 988..1019 CDD:238011
EGF_CA 1021..1057 CDD:238011
EGF_CA 1146..1180 CDD:238011
EGF_CA 1184..1219 CDD:238011
EGF_CA 1221..1265 CDD:238011
EGF_CA 1267..1305 CDD:238011
NL 1442..1479 CDD:197463
LNR 1 1449..1489
Notch 1487..1522 CDD:278494
LNR 2 1490..1531
Notch 1525..1561 CDD:278494
LNR 3 1532..1571
NOD 1567..1618 CDD:284282
NODP 1662..1719 CDD:284987
Interaction with PSEN1. /evidence=ECO:0000250|UniProtKB:P46531 1718..1750
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1770..1798
Ank_2 <1863..1948 CDD:289560
ANK repeat 1870..1915 CDD:293786
ANK 1912..2024 CDD:238125
ANK repeat 1917..1948 CDD:293786
ANK 1 1917..1946
Ank_2 1922..2015 CDD:289560
HIF1AN-binding 1937..1945
ANK repeat 1950..1981 CDD:293786
ANK 2 1950..1980
ANK 1979..2103 CDD:238125
ANK repeat 1984..2015 CDD:293786
ANK 3 1984..2013
Ank_2 1989..2081 CDD:289560
HIF1AN-binding 2004..2012
ANK repeat 2017..2081 CDD:293786
ANK 4 2017..2046
ANK 5 2050..2079
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2140..2185
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2382..2428
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2440..2531
DUF3454 2454..2516 CDD:288764
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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