DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpy and AgaP_AGAP009763

DIOPT Version :9

Sequence 1:NP_001260032.1 Gene:dpy / 318824 FlyBaseID:FBgn0053196 Length:22949 Species:Drosophila melanogaster
Sequence 2:XP_318851.4 Gene:AgaP_AGAP009763 / 1279171 VectorBaseID:AGAP009763 Length:920 Species:Anopheles gambiae


Alignment Length:1215 Identity:299/1215 - (24%)
Similarity:408/1215 - (33%) Gaps:443/1215 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   901 CRQGYERNSENGQCQDVDECSVQRGKPACGLNALCKNLPGSYECRCPQGHNGNPFIMCEICNTPE 965
            |.:||....        |||     .|:|.|             :|..|.          |..|:
Mosquito    10 CCEGYHTVG--------DEC-----LPSCRL-------------KCIFGE----------CVAPD 38

  Fly   966 -CQCQSPYKLVGNSCVLSGCSSGQACPSGAECISIAGGVSYCACPKGYQTQPDGSCVDVDECEER 1029
             |:|.|.|:.|.:......|.  .||.:| :|::    .:.|.|.:||:.  ||:.   ..|..:
Mosquito    39 TCECYSGYQKVNDHRCEPICE--VACENG-QCVA----PNVCLCDEGYER--DGTS---GSCRRK 91

  Fly  1030 GAQLCAFGAQCVNKPGSYSCHCPEGYQGDAYNGLCALAQRKCAADRECAANEKCIQPGECVCPPP 1094
            ..:.|.|| :||:.    .|.|.|||:.||.:|...:.|  |.  .|| .|.||:.|..|.|.|.
Mosquito    92 CDRACRFG-RCVDD----VCQCDEGYRPDATDGNVCVPQ--CT--EEC-QNGKCVLPNVCQCDPG 146

  Fly  1095 YFLDPQDNNKCKSPCERFPCGINAKCTPSDPPQCMCEAGFKGDPLLGCTDEDECSHL---PCAYG 1156
            |.|..|.|..|:..|.. .|. |..|.  .|.||.|:.|::.|      |.::|..:   || .|
Mosquito   147 YTLSTQSNVTCEPVCSE-GCA-NGNCI--GPDQCACQEGYELD------DSNQCVPVCLKPC-QG 200

  Fly  1157 AYCVNKKGGYQCVCPKDYT-GDPYKSGCIFESGTPKSKCLSNDDCASNL---------------- 1204
            ..|:   ...:|.|.:.|: .:...|.|:.....|   |::.|..|.|:                
Mosquito   201 GQCI---APGRCSCGEGYSPAEDDNSLCLPSCSEP---CVNGDCVAPNVCVCHANYRPRDDRTPH 259

  Fly  1205 --------ACLEGSCVSPCSSLLCGSNAYCETEQHAGWCRCRVGYVKNGD-GDCVSQCQDVICGD 1260
                    .|..|.|..|                  |.|.|..|:|.|.. |.|...|.:. |.:
Mosquito   260 VCVPDCPKGCAHGECFGP------------------GVCVCGKGFVYNETLGGCEPFCTEP-CRN 305

  Fly  1261 GALCIPTSEGPTCKCPQGQLGNPFPGGSCSTDQCSAARPCGERQICINGRCKERCEGVVCGIGAT 1325
            | :||   .|..|:|.:|...:|.....| ...||  :|      |::|         :|.....
Mosquito   306 G-VCI---GGNQCQCHEGYQLDPKTSSKC-VPHCS--KP------CVHG---------ICVAPDV 348

  Fly  1326 CD-------RNNGKCICEPNFVGNPDLICMPPIEQAKCSPGCGENAHCEYGLGQSRCACNPG--- 1380
            ||       ..|.|.:|||                 |||.|| .|..|   :....|.|:.|   
Mosquito   349 CDCKKGYVKSENSKNVCEP-----------------KCSKGC-SNGRC---VAPDHCECHKGYIA 392

  Fly  1381 TFGNPYEGCGAQSKNVCQPNSCGPNAECRAVGNHISCLCPQGFSGNPYIGCQDVDECANKPCGLN 1445
            |...|:......|              ..:..|..|.:|      .||        |.|| | :|
Mosquito   393 TSSFPFVSYSLSS--------------ISSAANSKSSIC------TPY--------CKNK-C-VN 427

  Fly  1446 AACLNRAGGFECLCLSGH--AGNPYSSCQPIESKFCQDA------------NKCQCNERVECPEG 1496
            |.|:...   .|.||:||  |.|..:.|:||    |:||            |.|:||      ||
Mosquito   428 AYCIRPN---VCQCLAGHRFADNSTNVCEPI----CEDALVDCSNGRCTQPNVCECN------EG 479

  Fly  1497 YS---------CQKGQCKNLCSQASCGPRAICDAGNCICPMGYIGDPHDQVHGCSIRGQCGNDAD 1552
            |:         |:...|:..|....|     .:.|.|:|..||....|                 
Mosquito   480 YTLAIRNGRMLCEPIACREHCVNGYC-----VEEGRCVCHPGYQPSQH----------------- 522

  Fly  1553 CLHSEICFQLGKGLRKCVDACSKIQCGPNALCVSEDHRSSCICSDGFFGNP--SNLQVGCQPE-- 1613
             .|| ||..:      |...|.      |.:|::.   ::|:|:.|:...|  .:.:..|.|.  
Mosquito   523 -FHS-ICEPM------CEGGCE------NGVCIAP---NTCVCNPGYARLPGGDSCEASCDPNVV 570

  Fly  1614 ---RTVPEEEDKCKSDQDCSRGYGCQASVNG-----IKECINLCSNVVC-GPNELCKINPAGHAI 1669
               ..|....::|:    |..||..:||.||     ...|...|:|..| .|||           
Mosquito   571 DCYNGVCRGANQCQ----CLEGYYLRASPNGGPYECAPVCDGGCANGRCLAPNE----------- 620

  Fly  1670 CNCAESYVWNPVVSSCEKPSLPDCTSDANCPDASACR----------PDVL--GVLKCVAICDAF 1722
            |.|.:.|.:|..:..|:...:|.|. :..|...:.|:          ||.|  ...:|...||  
Mosquito   621 CLCNDGYEYNGEMDRCDPVCVPSCV-NGQCVAPNVCQCLEGYVPVEDPDSLEESPFECAPYCD-- 682

  Fly  1723 TCPANSVCVARQHQGRCDCLNGFVGNPN------------DRNGCQPAQKHHCRNHAECQ---ES 1772
               ||.|          :|..|..|.||            |:.|.|           .|:   |.
Mosquito   683 ---ANVV----------NCTFGICGGPNVCRCFDDFYSTTDQLGRQ-----------TCELLPEP 723

  Fly  1773 EACIKDESTQTLGC-RPACDTVKCGPRAVC-VTNNHQAQCQCPPGPFAGDPYDPFNGCQSVPC-- 1833
            ..|:|:...:...| :.:|..|...|..|| ||        |||.|      .|...|..|.|  
Mosquito   724 VDCVKEPVKERSDCPKLSCPEVVLPPPPVCNVT--------CPPPP------PPPTPCPKVVCPT 774

  Fly  1834 ------------VYNHDCPPSQMCNRMTHTCFDVCDEESCGDNAICLAEDHRAVCQCPPGFKGDP 1886
                        :....|||.|||                 .:.||....       ||.....|
Mosquito   775 VPPTKPTTRAPPIVPVTCPPVQMC-----------------PDVICPTVP-------PPECPTTP 815

  Fly  1887 LPEVACTK-QGGCAAGTCHPSAICEVTPEGPVCKCPP---LFVGDAKSGGCRP--DGQCPNGDAD 1945
            .||..|.: ...||.|.|         .|..||.|.|   |.||......|:|  .|.|.||...
Mosquito   816 TPEPLCDELYVNCAHGDC---------IEQNVCSCHPGYQLAVGPESIVHCQPVCSGDCTNGICT 871

  Fly  1946 CPANTICAGGV-------CQNPCDNACGSNAECKVINRKPVCSCP 1983
            .|...:|..|.       |:..|:.|||..|.|...|   ||:||
Mosquito   872 EPDVCVCLPGYVETLEGQCEPYCEEACGEGAYCAQPN---VCACP 913

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpyNP_001260032.1 EGF_3 137..166 CDD:289699
EGF_CA 212..247 CDD:238011
EGF_CA 255..>286 CDD:214542
EGF_CA 298..331 CDD:238011
EGF_CA 338..373 CDD:238011
EGF_CA 413..456 CDD:238011
EGF_CA 457..490 CDD:238011
EGF_CA 497..>529 CDD:214542
EGF_CA 580..>612 CDD:214542
EGF_3 676..702 CDD:289699
EGF_CA 1022..1056 CDD:214542 10/33 (30%)
EGF_CA 2227..2260 CDD:238011
EGF_CA 2393..>2422 CDD:214542
DUF4758 4088..4282 CDD:292572
DUF4696 4127..4678 CDD:292395
DUF4758 4275..4448 CDD:292572
DUF4758 4377..4574 CDD:292572
DUF4758 4581..4754 CDD:292572
DUF4758 4683..4847 CDD:292572
DUF4758 4785..4964 CDD:292572
DUF4696 4841..5385 CDD:292395
DUF4758 4887..5098 CDD:292572
DUF4758 5193..5371 CDD:292572
DUF4758 5294..5487 CDD:292572
DUF4758 5445..5650 CDD:292572
DUF4758 5700..5877 CDD:292572
DUF4696 5756..6396 CDD:292395
DUF4758 5802..5979 CDD:292572
DUF4758 5964..6171 CDD:292572
DUF4758 6181..6360 CDD:292572
DUF4696 6339..6999 CDD:292395
DUF4758 6662..6839 CDD:292572
DUF4758 6764..6941 CDD:292572
DUF4758 6866..7045 CDD:292572
DUF4758 6968..7179 CDD:292572
DUF4696 7024..7569 CDD:292395
DUF4758 7172..7383 CDD:292572
DUF4696 7330..7964 CDD:292395
DUF4758 7400..7587 CDD:292572
DUF4758 7538..7707 CDD:292572
DUF4758 7798..7979 CDD:292572
DUF4758 7946..8126 CDD:292572
YppG 18767..>18832 CDD:290883
Med25_SD1 18795..18955 CDD:288132
MISS 19026..19258 CDD:292450
ZP 22576..22811 CDD:214579
Zona_pellucida <22714..22810 CDD:278526
AgaP_AGAP009763XP_318851.4 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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