DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpy and AgaP_AGAP000468

DIOPT Version :9

Sequence 1:NP_001260032.1 Gene:dpy / 318824 FlyBaseID:FBgn0053196 Length:22949 Species:Drosophila melanogaster
Sequence 2:XP_310626.5 Gene:AgaP_AGAP000468 / 1271772 VectorBaseID:AGAP000468 Length:866 Species:Anopheles gambiae


Alignment Length:975 Identity:251/975 - (25%)
Similarity:339/975 - (34%) Gaps:281/975 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly  6746 ETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTGG- 6809
            ||..:||:|.|.|..........|  ||.     |.|.|.:.:.:|..|.|.........:|.| 
Mosquito    38 ETVGSLPADETDRCSGAYYRCELR--PTD-----SVPVPVAAQCSVGRVYSREARQCVDAATVGC 95

  Fly  6810 ---------QVTEQTTSSPSEVRTTIGLEESTLPSRSTDRTSPSESPETPTTLPSDFITRPHSDQ 6865
                     .|..|.|||                .|..|..:|.        ..:.|:...::|.
Mosquito    96 SGIAFAGPRDVGFQCTSS----------------GRFPDLDAPD--------CKAYFLCTKNTDG 136

  Fly  6866 TTESTR-DVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTGGQVTEQTTSSPSEVRTTIG 6929
            :....| ..|.|..|   :|...|..::.|:|..:.:|..|..||.  ||......|.|      
Mosquito   137 SLIPARVTCPGTTIF---SPEKMSCVSSPPNVCPQASTTAPPPSTA--VTPGAFVCPGE------ 190

  Fly  6930 LEESTLPSRSTDRTSPSESPETPT---TLPSDFITRPHSDQTTESTRDVPTT--RPFEASTPSS- 6988
                       .|.:..:||:..|   .|.|.      |....:..|...:.  .|.|.|..|| 
Mosquito   191 -----------GRYANEQSPDCQTYYLCLYSG------SSLVAQLARCASSMVFSPAEGSCVSSD 238

  Fly  6989 --ASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSTDRTTPSESP 7051
              :......||.|:.|||:         .|.|:|..||   |.|.:   |.|..:|...||..|.
Mosquito   239 QYSCPNLVTPSPTVPTTTS---------TTSQSTPEPS---TNIPL---TTPGSATPEPTPELST 288

  Fly  7052 ETPTTLPSDFTTRPHSDQTTESSRDVPTTQPFEASTPRPVTLQTAVLPVTSETTTNVPIGSTGGQ 7116
            ..|.|.|...|..|    |.|.|..:|.|.|..| ||:|          |.|.:|.:|: :|.|.
Mosquito   289 NIPLTTPGSATPEP----TPEPSTIIPLTTPGSA-TPKP----------TPEPSTIIPL-TTPGS 337

  Fly  7117 VTEQTTSSPSEVRTTIRVEESTLPSRSTDRTTPSESPETPTTLPSDFTTRPHSDQTTESSRDVPT 7181
            .|.:.|..||   |.|.:   |.|..:|.:.||..|...|.|.|...|:.|    |.|.|..:|.
Mosquito   338 ATPKPTPEPS---TIIPL---TTPGSATPKPTPEPSTIIPLTTPGSATSEP----TPEPSTIIPL 392

  Fly  7182 TQPFESSTPRPVTLETAVPPVTSETTTNVPIGSTGGQVTEQTTPSPSEVRTTIRIEESTFPSRST 7246
            |.| .|:||.|          |.|.:||:|: :|.|..|.:.||.||   |.|.:   |.|..:|
Mosquito   393 TTP-GSATPEP----------TPEPSTNIPL-TTPGSTTPKPTPEPS---TIIPL---TTPGSAT 439

  Fly  7247 DRTTPSESPETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFESSTPRPVTLEIAVPPVTSETTTN 7311
            ...||..:...|.|.|...::.. .:.|.|.|.::|.|.|..|||           ..|.|.|||
Mosquito   440 SEVTPELTTNIPLTTPGTASSST-VELTPEPTTNIPLTTPGPSST-----------STTPEATTN 492

  Fly  7312 VAIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSTDRTTPSESPETPTTLPSDFTTRPHSDQT 7376
            :.: :|.|..|..||:.|                    :|||.|.|...|..|           |
Mosquito   493 IPL-TTPGTGTASTTNLP--------------------QTTPGEGPSPTTPAP-----------T 525

  Fly  7377 TESTRDVPTTRPFEASTPSPASLETTVPSVTLETTTSVPMGSTGGQVTGQTTAPPSEVRTTIRVE 7441
            ...|..:|.|.| .|.||:..|:.....:.|.|..|.:|:.:|.|.....||...:...||..|:
Mosquito   526 AAPTTAIPLTTP-GAVTPTTPSVPVPTTTATPEPRTDLPLTTTPGLEPSSTTTDAATATTTDSVD 589

  Fly  7442 ESTLPSRSTDRTPPSESPETPT-TLPSDFTTR------------PHSDQTTESSRDVPTTQPFES 7493
                   .||.|..|::.:..| |||:..||.            |..|.|...|..:.......:
Mosquito   590 -------GTDTTDRSDATDGATNTLPTTTTTTSGAFQCPNEGRFPSPDATGCESYVLCVRNSLGT 647

  Fly  7494 STPRPVTLEIAVPPVTSETTTNVPIGSTGGQVTGQTTATPSEVRTTIGVEESTLPSRSTDRTTPS 7558
            .||    |:...||.|..:.|.....:......||.|.             |..|..:|..|.|.
Mosquito   648 LTP----LQFTCPPTTIFSPTRAMCVTAALHTCGQETT-------------SVAPPATTTTTVPP 695

  Fly  7559 ESPETPTTLP-SDFTTRPHSDQ---------------------------------TTESTRDVPT 7589
            ..|.|||... .|....|:.|.                                 .|:::|.|..
Mosquito   696 PPPPTPTPFQCPDVGRFPNPDSLYCKSYYLCLYSLADGNTNLISVELSCPTGAIFATDASRCVKE 760

  Fly  7590 TRPFE---------ASTPSPASLETTVPSVTLETTTNVPIGSTGGQVTGQTTATPSEVRTTIGVE 7645
                |         |:|..|   |||..:.|..|||..            ||.||:...||:|:|
Mosquito   761 ----EGYRCGVGGGATTAGP---ETTTTAATTTTTTTT------------TTTTPAPTTTTLGLE 806

  Fly  7646  7645
            Mosquito   807  806

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpyNP_001260032.1 EGF_3 137..166 CDD:289699
EGF_CA 212..247 CDD:238011
EGF_CA 255..>286 CDD:214542
EGF_CA 298..331 CDD:238011
EGF_CA 338..373 CDD:238011
EGF_CA 413..456 CDD:238011
EGF_CA 457..490 CDD:238011
EGF_CA 497..>529 CDD:214542
EGF_CA 580..>612 CDD:214542
EGF_3 676..702 CDD:289699
EGF_CA 1022..1056 CDD:214542
EGF_CA 2227..2260 CDD:238011
EGF_CA 2393..>2422 CDD:214542
DUF4758 4088..4282 CDD:292572
DUF4696 4127..4678 CDD:292395
DUF4758 4275..4448 CDD:292572
DUF4758 4377..4574 CDD:292572
DUF4758 4581..4754 CDD:292572
DUF4758 4683..4847 CDD:292572
DUF4758 4785..4964 CDD:292572
DUF4696 4841..5385 CDD:292395
DUF4758 4887..5098 CDD:292572
DUF4758 5193..5371 CDD:292572
DUF4758 5294..5487 CDD:292572
DUF4758 5445..5650 CDD:292572
DUF4758 5700..5877 CDD:292572
DUF4696 5756..6396 CDD:292395
DUF4758 5802..5979 CDD:292572
DUF4758 5964..6171 CDD:292572
DUF4758 6181..6360 CDD:292572
DUF4696 6339..6999 CDD:292395 59/271 (22%)
DUF4758 6662..6839 CDD:292572 24/102 (24%)
DUF4758 6764..6941 CDD:292572 37/187 (20%)
DUF4758 6866..7045 CDD:292572 45/187 (24%)
DUF4758 6968..7179 CDD:292572 66/215 (31%)
DUF4696 7024..7569 CDD:292395 159/558 (28%)
DUF4758 7172..7383 CDD:292572 61/210 (29%)
DUF4696 7330..7964 CDD:292395 85/372 (23%)
DUF4758 7400..7587 CDD:292572 49/233 (21%)
DUF4758 7538..7707 CDD:292572 34/151 (23%)
DUF4758 7798..7979 CDD:292572
DUF4758 7946..8126 CDD:292572
YppG 18767..>18832 CDD:290883
Med25_SD1 18795..18955 CDD:288132
MISS 19026..19258 CDD:292450
ZP 22576..22811 CDD:214579
Zona_pellucida <22714..22810 CDD:278526
AgaP_AGAP000468XP_310626.5 CBM_14 620..671 CDD:279884 11/54 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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