back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpy and ppp1r12a

DIOPT Version :9

Sequence 1:	NP_001260032.1	Gene:	dpy / 318824	FlyBaseID:	FBgn0053196	Length:	22949	Species:	Drosophila melanogaster
Sequence 2:	XP_031754809.1	Gene:	ppp1r12a / 100493563	XenbaseID:	XB-GENE-5896537	Length:	1064	Species:	Xenopus tropicalis

Alignment Length:	913	Identity:	192/913 - (21%)
Similarity:	298/913 - (32%)	Gaps:	259/913 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  4184 RPFEASTPSPASL---ETTVPSVTLETTTN----DPIGSTGGQVTEQTTSSPSEVRTTIGLEEST 4241
            :.|:..||..|:.   :.....:.:|...|    :.:|.|...|.::...|..|   .:..:::.
Frog   228 KDFDGWTPLHAAAHWGKEEACKILVENFCNVEAVNKVGQTALDVADEDILSYLE---ELQKKQNL 289

  Fly  4242 LPSRSTDRTTP-SESPETPTTLPSDFITRPHSDQTTESTRDVPTTRPFEASTPSSASLETTVPSV 4305
            |.|...::.:| .||                  .|||:.:.:.|.:..|..........:.:.|:
Frog   290 LLSEKQEKKSPLIES------------------STTENNQSLKTLKNKETLIIEQEKTVSAIDSL 336

  Fly  4306 TLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTTLPSDFTT 4370
            ..|....    ...|:..|.:.||..|.......|..|..::|........|...|....:..::
Frog   337 EEEKADE----EDEGKKDESSCSSEEEEEEDSESEAETDKTKSLSSVNSINSNSIPQASVTAVSS 397

  Fly  4371 RPHSEQTTESTRDVPTT--RPFEASTPSPASLETTVPS---VTLETTTNVPIGSTGGQVTGQTTS 4430
            ..||.|.|      ||:  :.:|...|....:||..|:   ..|..|..|.:.|.|.:....|..
Frog   398 TVHSGQVT------PTSPVKKYEFIAPFMPVVETMHPTSWRQGLRKTGIVLVPSKGDKSLFPTPP 456

  Fly  4431 SPSEVRTTIRVEESTLPSRSADRTTPSESPETPTTLPSDFITRPHSEKTTESTRDVPTTRPFEAS 4495
            ..:..:...|.:||....|...|.|.|....:..|          :.|..:..||. |.....||
Frog   457 GKTSPKEEDRKDESPASWRLGLRKTGSYGALSEIT----------ASKEAQKERDF-TGVMRSAS 510

  Fly  4496 TPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTTLSE 4560
            :|..:|        ||:....    ...|:.......:|            |:|.|.|..:.:.|
Frog   511 SPRLSS--------TLDNKEK----EKDGRGARLAYVAP------------TIPRRLASTSDIEE 551

  Fly  4561 SPETPTTL-----PSDFTIRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTS------E 4614
            .....::|     .|.:|.|...|.             |:.:|.....|.|:....:|      :
Frog   552 KENRDSSLGFLRGSSSYTRRKWDED-------------FKKNTSVNELLNTSYQRSSSFGRRQDD 603

  Fly  4615 TTTNVPIGSTGGQVTGQTTAPPSEFRTTIRVEESTLPSRSTDRTTPSESPETPTILPSDSTTRTY 4679
            ..:::|.||| ..||....|  ..:.:||....||:.|.|.              |||.::.|.:
Frog   604 LVSSIPPGST-ATVTSSGLA--RSYSSTINSGRSTVSSSSG--------------LPSSTSNRFW 651

  Fly  4680 SDQTTESTRDVPTTRPFEASTP-SPASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVR- 4742
            :|.::|..:|..:|   ..:.| :|..|.||..|.|:.||      |||      |..|.:|||
Frog   652 ADDSSEKDKDTVST---AVTIPVAPTILNTTSTSTTMTTT------STG------TVPSSAEVRE 701

  Fly  4743 ------TTIRVEES----TLPSRSADRTTPSESPETPTTLPSDFITRPHSEKTTESTRDVPTTRP 4797
                  |.:|.|||    ...||.|.::..|....|.|.|       ..:|||....|  ||||.
Frog   702 RRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDL-------QEAEKTIGRNR--PTTRE 757

  Fly  4798 FEASTPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRT 4862
                                             |..|:......|.:.    ::....:|:
Frog   758 ---------------------------------QENEEKEKQDKEKQE----DKKEFENRN---- 781

  Fly  4863 TPSESPETPTTLPSDFITRPHSEKTTESTRDVPTTRPFEASTPSSASLETTVPSVTLETTTNVPI 4927
                         .||  |....::||.|  :...|| ..:|||:.||.::..|:...:..|.|.
Frog   782 -------------DDF--RQRYARSTEET--IQRYRP-SFTTPSTISLSSSSSSIYTSSQLNRPN 828

  Fly  4928 GSTG----------------------GQVTEQTTSSPSEVRTTIRVEESTLPSRSTDRTTPSESP 4970
            ..||                      |:..|:...|          |:.:.|....:|..|.|..
Frog   829 SLTGISSSYSNLSRLSSKDPLKDKLDGEKKEEDKES----------EDKSQPKSIRERRRPREKR 883

  Fly  4971 ETP----TTLPSDFTTRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTLETTTNVP-IG 5030
            .:.    .|..||...:.|...|.|.|...      |..|.| .|..||..|..:.|....| ||
Frog   884 RSTGVSYWTQDSDENEQDHQSDTDEGTNKK------ENQTDS-FSRYTTGLSSAISTDRYDPVIG 941

  Fly  5031 STG 5033
            .:|
Frog   942 QSG 944

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.