Protein Alignment dpy and muc4

DIOPT Version :10

• Sequence 1: NP_001260032.1
• Gene: dpy / 318824
• FlyBaseID: FBgn0053196
• Length: 22949
• Species: Drosophila melanogaster
• Sequence 2: XP_031757776.1
• Gene: muc4 / 100485162
• XenbaseID: XB-GENE-852599
• Length: 5393
• Species: Xenopus tropicalis
• Alignment Length: 7333
• Identity: 1549/7333 - (21%)
• Similarity: 2157/7333 - (29%)
• Gaps: 3037/7333 - (41%)

  Fly  2133 ASNQCPSGHMCI----GNQCNLPC------TKTASCAVGERCYQQVCRKVCYTSNNCLAGE---- 2183
            :|||.|.....:    |....:|.      ||.||..:...  ..:...|.|:|.:..|.:
 Frog   444 SSNQTPITSTTVVQTAGYATTVPALITTATTKNASLYISTA--SVISTSVGYSSMSTHANQVIST 506

  Fly  2184 ----------ICNSDRTCQPG-CDSDADCPPTELCLTGKCKCATGFIGTPFG--CSDIDECTEQP 2235
                      :||  ..|..| |:..   |.|   .|..|.|:.||...|..  |.||:||....
 Frog   507 TAINTTTFPVVCN--LPCMNGWCNIK---PET---ATPVCSCSAGFSPDPSNTLCIDINECVLNL 563

  Fly  2236 CHASARCENLPGTYRCVCPEGTVGDGYSQPGCSQPRQCHKPDDCANNLACIHGKCTDPCLHTVCG 2300
            .:....|.|..|.|.|.|.     ||| :.....|:.|.|.|.|.::          ||.
 Frog   564 DNCQQLCFNTIGGYFCSCQ-----DGY-EKNQQSPQNCDKIDYCKSS----------PCK----- 607

  Fly  2301 INANCQSEGHEALCSCPAGFLGDPNDTGVGCFKVECIDHVDCAGDRACDAETNRCIKPCDLTSCG 2365
             |..|||......|||.||:.|                       ..||.:.|.    |:.:.|.
 Frog   608 -NGQCQSGLLSYTCSCNAGWHG-----------------------TNCDTDVNE----CESSPCA 644

  Fly  2366 KGNCQVRDHKATCACYEGYQLVNDVC-EDINECLSQPCHSTAFCNNLPGSYSCQCPEGLIGDPLQ 2429
            ||.|........|.|..|:  ....| :|:|||...||.:...|.|..|||:|.|..|..|
 Frog   645 KGTCNNTLGSFVCICMAGW--TGPTCNKDVNECNLTPCQNGGQCTNTLGSYTCSCVPGYQG---- 703

  Fly  2430 AGCRDP-NECLSDADCPASASCQNSRCRSPCERQNACGLNANCQAQAHQAICTCPLNSRGDPTIE 2493
            ..|... |||||                :||..      .|.|.:..:...|||
 Frog   704 VNCEQKINECLS----------------TPCWN------GATCNSLINAFSCTC----------- 735

  Fly  2494 CVHIECADNDDCSGEKACLDSKCIDPCSLPNACGALARCSVQNHIGVCSCEAGSTGDAKLGCVQL 2558
                                        :|...|..             ||           |::
 Frog   736 ----------------------------VPGYTGRF-------------CE-----------VEI 748

  Fly  2559 QYCQQDGQCAQGSICSHGI--CSPLCSTNRDCISEQLCLQGVCQGTCKSNSSCPQFQFCSNNICT 2621
            ..|..: .|..|.:|...:  .|..|:.|         .||:               ||..::
 Frog   749 NECYSN-PCKNGGVCIDRVNGFSCRCTVN---------WQGL---------------FCDQDV-- 786

  Fly  2622 KELECRSDSECGEDETCLSDAYGRAKCESVCLGRAACGRNAECVARSHAPDCLCKEGFFGDAKSG 2686
                    :||                   ..|.:.|..|..|.....:..|.|..|:.||
 Frog   787 --------NEC-------------------TTGLSRCSVNGNCTNTLGSYTCACNNGYSGD---- 820

  Fly  2687 CRKIECTSDDDCSNDKSCDNHMCKIACLIGQPCGENALCTTEHHQQVCHCQPGFSGDPRVRCDVI 2751
                                         |..|.|..|.             .:|.|.::...:.
 Frog   821 -----------------------------GFTCREKRLF-------------DYSSDIKITQRLK 843

  Fly  2752 DFCRDA-------PCGPGARCRNA----------------RGSYKCTCPPGLVGDPY-----NEG 2788
            ||....       |.|      |:                |..|:   |..:...||     |:.
 Frog   844 DFTSPLISVPMRFPFG------NSFYSNLYITDNGVIMFQRYFYE---PMYIFSYPYSHFYSNDY 899

  Fly  2789 CRSSVECETNEDCPPHAACTKTNG-VAKCRDVCAQ---LQCGPNAECVPKGHVAQCACRSGYDGQ 2849
            .|           ||..|....:. :::..|:..|   .|..||.:...|..: :...:: |...
 Frog   900 SR-----------PPMIAVFWADADMSQTGDLYYQTYDFQQAPNYQAAFKTEL-ETEIKT-YFNM 951

  Fly  2850 P-----ADRVAGCKPLPSPCQVTGDCPTNTYCSDSVCKPACVLDTECGAFEVC-----QGGQ--- 2901
            |     |.::...|.||.|........|||:        ..||.|: |.:..|     .||.
 Frog   952 PFTALWAIKITWAKVLPYPSYYFTSANTNTF--------QAVLVTD-GIYSFCLMRFDDGGMNWK 1007

  Fly  2902 ----------------------------CFNPCLQPQACGQNAECVMQNHLKQCHCPEGFTGDSA 2938
                                        .||   .||....|        |:..:.|:.:.|.:.
 Frog  1008 YQALPTYYLPKMGYFSGEPHLNNNNNFPAFN---DPQTFSSN--------LQMIYTPDQYKGYNT 1061

  Fly  2939 KECVRVPVACDGECGPGYTCRDSMCLPVCHNDLECASN----EKCLKGSCMLTCRVDNDCFLGHV 2999
            ...             ||.        ....::..|:.    ::||...........:|......
 Frog  1062 NRI-------------GYW--------AYRLEMNTANTKNTWQQCLSWYYNEPYPYWSDYTSPCP 1105

  Fly  3000 CLHNKCVYGCHVDDDCSASESCRNDKCVNPCLENPC------------GPNAACSVSNHRASCSC 3052
            |.:.:.:|      |.|.:.|.|.::...|...:..            |....|   |:..|.|.
 Frog  1106 CSYWQAIY------DSSFTSSNRLNQYSFPRKSSDIFLSFQSAFPTFYGGGTRC---NYYWSGSL 1161

  Fly  3053 L----ESMVPNPTPQVGCVRSPPLECRENRDCGNGLACFESVCRPLCADDAGCLTNERCQQGVCK 3113
            :    |..:|.|........||.|:           ..|.....||....
 Frog  1162 IYGEKERFLPTPWIYDNSWWSPQLQ-----------NYFRHTALPLLISQ--------------- 1200

  Fly  3114 PLCRHDNECGHGELCLGLNCVPGCRSDQGCPPELSCVGQQCVDP-----CADPTACGTNAHCQTI 3173
               ...||....|.|..|.....|.......|...|.|.  :.|     ..||       |..|:
 Frog  1201 ---YQANEINPFENCCTLGSPYLCYLYSQKRPRDYCYGY--IQPRIGYFYGDP-------HINTL 1253

  Fly  3174 DHRKQCLCPEG------LDGNANVACKVP-RIA-CGRNEDCQ-SNQLCYAGSCQGKCR-----ND 3224
            |..:......|      :.||.....::. |.| .|.|...| :|.:..|.....:.:     :|
 Frog  1254 DGVQYTFNGLGEFIVVNVQGNNGTIFQLQGRTARAGINGTSQATNFVALAAEINSEMKVEWYLSD 1318

  Fly  3225 QNCLADERCMRGTCRTVCNTDEACAQGQICENRMCQTGCRTD----LSCATDE--------ACVN 3277
            :|....:  :.||..|:  :|...:.|.:......:.|.:..    :|.|...        |.::
 Frog  1319 KNTTFVK--VNGTEFTL--SDNITSLGTVTLETTTEQGLKASFVGGISVAVSAAFGALSFVATLD 1379

  Fly  3278 KKCQNPCRTPGQCG----QCADCLVVNH-------GVQCQCPAAFMGDGLTGCQLPPERC----- 3326
            ...||  :|.|..|    ...|..:.::       ||.....:|....|:|....|....
 Frog  1380 SSYQN--KTEGLLGLYDENVTDDFMYSNGTFLSYDGVTLPSDSAIFEMGMTWKTTPNSSIFSYNS 1442

  Fly  3327 --------------------------------HPDCECDENGAYCAPKCSRTEDCACGQ------ 3353
                                            ..:..|..|.. |......|.:.|.||
 Frog  1443 TNNESWYTYNNNSFVPLFYDELLQTSNKTLIDSANATCKGNNE-CIFDILSTGNLAVGQATLGAA 1506

  Fly  3354 --QCARGKCRNKCGP------------KRQCTVG----------------------QLCERGACI 3382
              ..|:....|...|            ....||.                      .:...|..:
 Frog  1507 NSATAQANSMNNFPPDITGPTTISTTLNTSVTVNYTVTDQNNDQVILSLETDSKDITITANGTLV 1571

  Fly  3383 ------------------------------AGCKSNGDCAADQSCVNGKCSDP-CANEKACGRNA 3416
                                          ..|.:||.|..:|:     .|.| ..|.|..|
 Frog  1572 WTPTSSDPFNVTIQANDSKAITTFILTLVLCNCSNNGSCLFNQN-----TSIPNYPNFKVAG--- 1628

  Fly  3417 LCTVSEHRMLCYCPDGYEGEPSKECVQFECRVDTDCDSNKRCDQG-KCRNPCLEYGACGTNAQCR 3480
             |..:|.....||.|.::|     |::.:|.|::.|:..|....| .|       |||...
 Frog  1629 -CNCTEAWTGIYCEDDFDG-----CLENQCYVNSTCEDVKAPGVGFSC-------GACPAG---- 1676

  Fly  3481 VVGRKAQCSCPPDFFGNPTSECRPLEGGCSSKPCGENSKCTEVPGGYECACMDGCIGDAHQGCLC 3545
            :.|...||:...:.:.| .|.|..:              |...||||.|:||:|...:......|
 Frog  1677 MTGNGLQCADIDECYLN-ISNCEQI--------------CNNFPGGYSCSCMEGYQVNQTNSSKC 1726

  Fly  3546 GGPLVNACRD---QPCGLNAACHVLENNQAECYCPEDFPNGDAYVQCYLTTPKQDCRTLGC-EVG 3606
            ..  :|.|::   .|||.|..|..|..|.: |.|...: :|:..:.|   ....:|....| ...
 Frog  1727 ED--INECQNATYYPCGENTECINLPGNYS-CECQTGY-SGNPTLFC---ADINECALFPCPNTS 1784

  Fly  3607 GCVRQGYEYVCQQDTEQCYSDTDCPSEKSCLQGH----CSD--PCTMRGVCGLNALCKTVLHRPR 3665
            .|:.....|.|                 .||.|:    |:|  .|.....|..|::|...:....
 Frog  1785 ICINTNGSYTC-----------------DCLPGYNGTNCTDINECETNNTCPQNSMCNNTIGSYT 1832

  Fly  3666 CSCPSCHIGRPEIECKSDPKCVAEDTDPKTKEQIPCSTDSECPETLQCGQYGQCT--DPCNNPLF 3728
            |:|.:.:.|:                                          .||  |.|:...:
 Frog  1833 CNCNTGYSGQ------------------------------------------NCTDIDECSIGTY 1855

  Fly  3729 ICESNKKCETRRHQPVCICKSGFIVNEYGELTCAPDKRECYRDDDCASNMACSDGKCRNPCIVPL 3793
            .|..|..|........|.|.:||..|..          :|...::|.||.:..||
 Frog  1856 NCGPNSNCSNTVGSYRCACVTGFTGNGV----------QCEDINECMSNNSVCDG---------- 1900

  Fly  3794 GRAAICAENKSCEVQNHKPVCICMRDCQPSISICLRDAGCPASQACRKLKCVDPCEFATCAPNSP 3858
                    |.:|:..|...:|.|             |.|...:...    |||..|   |...|.
 Frog  1901 --------NSTCKNTNGSYICEC-------------DVGFTNNNGL----CVDVNE---CNSTSY 1937

  Fly  3859 CIVEDHKPICK--------FCPAGFIADAK-----NGCQKAKPGGNCTSNTDCSQAHQCGSSGKC 3910
            |..|..  |||        .|..|:|.|..     |.| ......||:||..||..     :|..
 Frog  1938 CTAEGQ--ICKNTVGSFECNCKTGYIMDNNTCIDINEC-ALNTTNNCSSNAFCSNI-----AGSY 1994

  Fly  3911 IDPCLTSCAG-GVKC---------VVSAHRVTICTCPATLTNNTDSNCTSTDITVGTTTQRIETT 3965
            :..|.::..| |..|         ..|...|::.|...|.||||      |.:|.||.::
 Frog  1995 VCLCYSNYTGDGFSCTEYVPTSIPTTSPTPVSLTTLTETTTNNT------TAVTTGTISE----- 2048

  Fly  3966 TDFINVKYTVMQLANQTEMRTRFTDIEAENETTGPYTTTTESYKTTKQLSSNPETETPTTLPSRP 4030
            |.|::|  |...:...:|:.|       |.:||..||                     |.|||..
 Frog  2049 TGFVSV--TSNNILISSELNT-------EAQTTLVYT---------------------TALPSGT 2083

  Fly  4031 TTRPFTDQTTEFTSEIPTITPMEGSTPTPSHLETTVASITSESTTREVYTIKPFDRSTPTPVSPD 4095
            :|.|.|..:...:||             |..|.:..:|.|...||
 Frog  2084 STEPGTSNSAVTSSE-------------PHSLSSETSSTTVLLTT-------------------- 2115

  Fly  4096 TTVPSITFETTTNIPIGTTRGQVTEQTTSSPSEKRTTIRVEESTLPSRSTDRTTPSESPETPTIL 4160
                  |.||.|.:|.|||                   ..|.:|.|..|....|.||
 Frog  2116 ------TSETATALPSGTT-------------------STETNTEPVTSNSAVTSSE-------- 2147

  Fly  4161 PSDSTTRTYSDQTTESTRDVPTTRPFEASTPSPASLETTVPSVTLETTTNDPIGSTGGQVTEQTT 4225
                                            |.||.:...|.|:..||          .:|..|
 Frog  2148 --------------------------------PHSLSSETSSTTVLVTT----------TSETAT 2170

  Fly  4226 SSPSEVRTTIGLEESTLPSRSTDRTTPSESPETPTTLPSDFITRPHSDQTTESTRDVPTTRPFEA 4290
            :.||...:|   |.||.|..|....|.||               |||
 Frog  2171 ALPSGTTST---ETSTEPVTSNSAVTSSE---------------PHS------------------ 2199

  Fly  4291 STPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTTPS 4355
              .||.:..|||...|.||.|.:|.|:|..:.|.:..:|.|.|                   |.|
 Frog  2200 --LSSETSSTTVLVTTSETATALPSGTTSTETTTEPVTSNSAV-------------------TSS 2243

  Fly  4356 ESPETPTTLPSDFTTRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTLETTTNVPIGST 4420
            |               |||             ..||.|:      .|.:.:.|.||.|.:|.|:|
 Frog  2244 E---------------PHS-------------LSFETSS------TTVLVTTTSETATALPSGTT 2274

  Fly  4421 GGQVTGQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTTLPSDFITRPHSEKTTESTRD 4485
            .                   .|.||.|..|....|.||               ||
 Frog  2275 S-------------------TETSTEPVTSNSAVTSSE---------------PH---------- 2295

  Fly  4486 VPTTRPFEASTPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPS 4550
                     |..|..|..|.:.:.|.||.|.:|.|:|..:.:.:..:|.|.|.::   |..:|.|
 Frog  2296 ---------SLSSEISSTTVLVTTTSETATALPSGTTSTETSTEPVTSNSAVTSS---EPHSLSS 2348

  Fly  4551 RSADRTTLSESPETPTTLPSDFTIRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSV---- 4611
            .::..|.|..:.||.|.|||..|    |.:||  |..|.:.....:|.|...|.||:..:|
 Frog  2349 ETSSTTVLVTTSETATALPSGTT----STETT--TEPVTSNSAVTSSEPHSLSFETSSTTVLVTT 2407

  Fly  4612 TSETTTNVPIGSTGGQVTGQTTAPPSEFRTTIRVEESTLPSRSTDRTTPSESPETPTILPSDSTT 4676
            ||||.|.:|.|:|.                   .|.||.|..|....|.||    |..|.|:
 Frog  2408 TSETATALPSGTTS-------------------TETSTEPVTSNSAVTSSE----PHSLSSE--- 2446

  Fly  4677 RTYSDQTTESTRDVPTTRPFEASTPSPASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEV 4741
                   |.||                    |.:.:.|.||.|.:|.|:|..:.:.:..:|.|.|
 Frog  2447 -------TSST--------------------TVLVTTTSETATALPSGTTSTETSTEPVTSNSAV 2484

  Fly  4742 RTTIRVEESTLPSRSADRTTPSESPETPTTLPSDFITRPHSEKTTESTRDVPTTRPFEASTPSSA 4806
            .::   |..:|.|..:..|....:.||.|..||.      :..|..:|..|.:.....:|.|.|.
 Frog  2485 TSS---EPHSLSSEISSTTVLVTTSETATAFPSG------TTSTETTTEPVTSNSAVTSSEPHSL 2540

  Fly  4807 SLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETP 4871
            |.||:..:|.:.||:|.......|..:.:|::.|             :.|.|||  |.||
 Frog  2541 SSETSSTTVLIITTSNTATALPSGTTSTETSTEP-------------VTSNSAD--TSSE----- 2585

  Fly  4872 TTLPSDFITRPHSEKTTESTRDVPTTRPFEASTPSSASLETTVPSVTLETTTNVPIGSTGGQVTE 4936
                      |||             ..||  |.|:..|.||    |.||.|.:|.|:|.
 Frog  2586 ----------PHS-------------LSFE--TSSTTVLVTT----TSETATALPSGTTS----- 2616

  Fly  4937 QTTSSPSEVRTTIRVEESTLPSRSTDRTTPSESPETPTTLPSDFTTRPHSEQTTESTRDVPTTRP 5001
                  :|.||                       |:.|:..:|.::.|||
 Frog  2617 ------TETRT-----------------------ESVTSNSADTSSEPHS--------------- 2637

  Fly  5002 FEASTPSPASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRT 5066
            ..:.|.|...|.||    |.||.|.:|.|:|.                   .|.||.|..|....
 Frog  2638 LSSETSSTTVLVTT----TSETATALPSGTTS-------------------TETSTEPVTSNSAV 2679

  Fly  5067 TPSESPETPTTLPSDFITRTYSDQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPI 5131
            |.||    |.:|.|:          |.||                    |.:.:.||||.|.:|.
 Frog  2680 TSSE----PNSLSSE----------TSST--------------------TVLVTTTSETATALPS 2710

  Fly  5132 GSTGGQVTGQTTAPPSEFRTTIRVEESTLPSRSTDRTTPSESPETPTTLPSDFTTRPHSDQTTES 5196
            |:|.                   .|.||.|..|....|.||               |||
 Frog  2711 GTTS-------------------TETSTEPVTSNSAVTSSE---------------PHS------ 2735

  Fly  5197 TRDVPTTRPFEASTPSPASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEEST 5261
                     ..:.|.|...|.||    |.||.|.:|.|:|.                   .|.||
 Frog  2736 ---------LSSETSSTTVLVTT----TSETATALPSGTTS-------------------TETST 2768

  Fly  5262 LPSRSADRTTPSESPETPTLPSDFTTRPHSEQTTESTRDVPATRPFEASTPSPASLETTVPSVTS 5326
            .|..|....|.||              |||             ..||.|:      .|.:.:.||
 Frog  2769 EPVTSNSAVTSSE--------------PHS-------------LSFETSS------TTVLVTTTS 2800

  Fly  5327 EATTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSTDRTSPSESPETPTTLPSDFTTRP 5391
            |..|.:|.|:|..:.|.:..:|.|.|
 Frog  2801 ETATALPSGTTSTETTTEPVTSNSAV--------------------------------------- 2826

  Fly  5392 HSDQTTECTRDVPTTRPFEASTPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRT 5456
                    |...|.:..||  |.|:..|.||    |.||.|.:|.|:|.           :|.||
 Frog  2827 --------TSSEPQSLSFE--TSSTTVLVTT----TSETATALPSGTTS-----------TETRT 2866

  Fly  5457 TIRVEESTLPSRSADRTTPSESPETPTLPSDFTTRPHSEQTTESTRDVPTTRPFEASTPSSASLE 5521
                  .::.|.|||  |.||              |||               ..:.|.|:..|.
 Frog  2867 ------ESVTSNSAD--TSSE--------------PHS---------------LSSETSSTTVLV 2894

  Fly  5522 TTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEFRTTIRVEESTLPSRSADRTTPSESPETPTLP 5586
            ||    |.||.|.:|.|:|.                   .|.||.|..|....|.||
 Frog  2895 TT----TSETATALPSGTTS-------------------TETSTEPVTSNSAVTSSE-------- 2928

  Fly  5587 SDFTTRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTGGQVTGQTTA 5651
                  |||             ..||.|:      .|.:.:.||||.|.:|.|:|.
 Frog  2929 ------PHS-------------LSFETSS------TTVLVTTTSETATALPSGTTS--------- 2959

  Fly  5652 PPSEVRTTIRVEESTLPSRSTDRTTPSESPETPTILPSDSTTRTYSDQTTESTRDVPTTRPFEAS 5716
                      .|.:|.|..|....|.||                            |.:..||.|
 Frog  2960 ----------TETTTEPVTSNSAVTSSE----------------------------PQSLSFETS 2986

  Fly  5717 TPSPASLETTVPSVTLETTTNVPIGSTGGQVTGQTTATPSEVRTTIGVEESTLPSRSTDRTSPSE 5781
            :      .|.:.:.|.||.|.:|.|:|.           :|.||
 Frog  2987 S------TTVLVTTTSETATALPSGTTS-----------TETRT--------------------- 3013

  Fly  5782 SPETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTG 5846
              |:.|:..:|.::.|||               ..:.|.|...|.||    ||||.|.:|.|
 Frog  3014 --ESVTSNSADTSSEPHS---------------LSSETSSTTVLVTT----TSETATALPSG--- 3054

  Fly  5847 GQVTEQTTSSPSEVRTTIGLEESTLPSRSTDRTSPSESPETPTTLPSDFITRPHSDQTTESTRDV 5911
                  ||||          |.||....|....:.||               |||
 Frog  3055 ------TTSS----------ESSTESDTSNSAVTSSE---------------PHS---------- 3078

  Fly  5912 PTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTGGQVTGQTTAPPSEVRTTIGVEESTLPSR 5976
                 ..:.:.|...|.||    ||||.|.:|.|:|                   ..|.||.|..
 Frog  3079 -----LSSESSSTIVLVTT----TSETATALPSGTT-------------------STETSTEPDT 3115

  Fly  5977 STDRTSPSESPETPTTLPSDFITRPHSEQTTESTRDVPTTRPFEASTPSPASLKTTVPSVTSEAT 6041
            |....:.||               |||               ..:.|.|...|.||    |||..
 Frog  3116 SNSAVTSSE---------------PHS---------------LSSETSSTTVLVTT----TSETA 3146

  Fly  6042 TNVPIGSTGQRIGTTPSESPETPTTLPSDFTTRPHSEKTTESTRDVPTTRPFETSTPSPASLETT 6106
            |.:|.|:|.....|.|..|....|:....|.       ::||:              |..:|.||
 Frog  3147 TALPSGTTSTDTSTEPDTSNSAVTSSEPQFL-------SSESS--------------STIALVTT 3190

  Fly  6107 VPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTLPSD 6171
                |.||.|.:|.|:|.                   .|.||.|..|....|.|| |:
 Frog  3191 ----TSETATALPSGTTS-------------------TETSTEPDTSNSAVTSSE-PQ------- 3224

  Fly  6172 FTTRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTGGQVTGQTTAPP 6236
                                     |..|..|..|.:.:.||||:|.:|.|
 Frog  3225 -------------------------SLSSETSSTTVLVTTTSETSTALPSG-------------- 3250

  Fly  6237 SEVRTTIGVEESTLPSRSTDRTSPSESPETPTTLPSDFITRPHSEQTTESTRDVPTTRPFEASTP 6301
                 ||..|.||.|..|....:.||               |||               ..:.|.
 Frog  3251 -----TISTESSTEPVNSNSAVTSSE---------------PHS---------------LSSETS 3280

  Fly  6302 SPASLKTTVPSVTSEATTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSTDRTTPSESP 6366
            |...|.||    |||.:|.:|.|:|                   ..|.||.|..|....|.||
 Frog  3281 STTVLVTT----TSETSTALPSGTT-------------------CTETSTEPDTSNSADTSSE-- 3320

  Fly  6367 ETPTTLPSDFTTRPHSEKTTESTRDVPTTRPFETSTPSPASLETTVPSVTLETTTSVPMGSTGGQ 6431
              |.:|.|:          |.||                    |.:.:.|.||.|::|.|:|.
 Frog  3321 --PQSLSSE----------TSST--------------------TVLVTTTSETATALPSGTTS-- 3351

  Fly  6432 VTGQTTAPPSEVRTTIRVEESTLPSRSTDRTSPSESPETPTTLPSDFITRPHSEKTTESTRDVPT 6496
                                                            |.|.:|..|.::.|
 Frog  3352 ------------------------------------------------TEPRTESVTSNSAD--- 3365

  Fly  6497 TRPFEASTPSSASSGNNCSISYFRNHYKCSNRFNRSADRTTPSESPETPTLPSDFTTRPHSEQTT 6561
                                                    |.||              |||
 Frog  3366 ----------------------------------------TSSE--------------PHS---- 3372

  Fly  6562 ESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTGGQVTGQTTAPPSEVRTTIRVEE 6626
                       ..:.|.|...|.||    ||||.|.:|.|:|..                   |.
 Frog  3373 -----------LSSETSSTTVLVTT----TSETATTLPSGTTSS-------------------ES 3403

  Fly  6627 STLPSRSTDRTTPSESPETPTILPSDFTTRPHSDQTTESTRDVPTTRPFEASTPRPVTLETAVPS 6691
            ||.|..|....|.||               |||..:..|:..|..|...|.:        ||:||
 Frog  3404 STEPDTSNSAVTSSE---------------PHSLSSESSSTIVLVTTTSETA--------TALPS 3445

  Fly  6692 VTLETTTNV-PIGSTGGQVTGQTTATPSEVRTTIRVEESTLPSRSTDRTTPSESPETPTTLPSDF 6755
            .|..|.|:. |:.|.....:.:.....||..:||.:..:|              .||.|.|||..
 Frog  3446 GTTSTETSTEPVTSNSAVTSSEPQFLSSESSSTIALVTTT--------------SETATALPSGT 3496

  Fly  6756 TTRPHSDQTTESTRDVPTTRP--FEASTPSPASLETTVPSVTSETTTNVPIGSTGGQVTEQTTSS 6818
            |:...|.:...|...|.::.|  ..:.:.|..:|.||    ||||.|.:|.|         |||:
 Frog  3497 TSTDTSTEPDTSNSAVTSSEPQFLSSESSSTIALVTT----TSETATALPSG---------TTST 3548

  Fly  6819 PSEVRTTIGLEESTLPSRSTDRTSPSESPETPTTLPSDFITRPHSDQTTESTRDVPTTRPFEAST 6883
                      |.||.|..|....:.||    |.:|.|:          |.||
 Frog  3549 ----------ETSTEPDTSNSAVTSSE----PQSLSSE----------TSST------------- 3576

  Fly  6884 PSPASLETTVPSVTSETTTNVPIGSTGGQVTEQTTSSPSEVRTTIGLEESTLPSRSTDRTSPSES 6948
                   |.:.:.||||:|.:|.|         |||:          |.||.|..|....:.||
 Frog  3577 -------TVLVTTTSETSTALPSG---------TTST----------ETSTEPVNSNSAVTSSE- 3614

  Fly  6949 PETPTTLPSDFITRPHSDQTTESTRDVPTTRPFEASTPSSASLETTVPSVTLETTTNVPIGSTGG 7013
                          |||               ..:.|.|:..|.||    |.||.|.:|.|:|.
 Frog  3615 --------------PHS---------------LSSETSSTTVLVTT----TSETATALPSGTTS- 3645

  Fly  7014 QVTEQTTSSPSEVRTTIRVEESTLPSRSTDRTTPSESPETPTTLPSDFTTRPHSDQTTESSRDVP 7078
                              .|.||.|..|....|.||               |||
 Frog  3646 ------------------TETSTEPVTSNSAVTSSE---------------PHS----------- 3666

  Fly  7079 TTQPFEASTPRPVTLQTAVLPVTSETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRS 7143
              ..||.|:      .|.::..||||.|.:|.|:|..:...::.:|.|.|
 Frog  3667 --LSFETSS------TTVLVTTTSETATALPSGTTSTETRTESVTSNSAV--------------- 3708

  Fly  7144 TDRTTPSESPETPTTLPSDFTTRPHSDQTTESSRDVPTTQPFESSTPRPVTLETAVPPVTSETTT 7208
                |.||               |||..:..||..|..|                   .||||.|
 Frog  3709 ----TSSE---------------PHSLSSETSSTTVLLT-------------------TTSETAT 3735

  Fly  7209 NVPIGSTGGQVTEQTTPSPSEVRTTIRIEESTFPSRSTDRTTPSESPETPTTLPSDFTTRPHSDQ 7273
            .:|.|:|.                   .|.||.|..|....|.||    |.:|.|:.::......
 Frog  3736 ALPSGTTS-------------------TETSTEPVTSNSADTSSE----PHSLSSEISSTTVLVT 3777

  Fly  7274 TTESTRDVPTTRPFESSTPRPVTLEIAVPPVTSETTTNVAIGSTGGQVTEQTTSSPSEVRTTIRV 7338
            ||..|...|.:        |.::.|.:..||||    |.||.|:|.......|||.:.:.||...
 Frog  3778 TTSETATAPPS--------RTISTETSTEPVTS----NSAITSSGPHSLSSETSSTTVLVTTTSE 3830

  Fly  7339 EESTLPSRSTDRTTPSESPETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFEASTPSPASLETTV 7403
            ..:.||| .|..|..|..|:|..:..:....|..|.:.:.:|....||...|.:|   .::.||.
 Frog  3831 TATALPS-GTISTETSTEPDTSNSAITSSGPRSLSSENSSTTGPTTTTAAAEKTT---TNVPTTT 3891

  Fly  7404 PSVTL--ETTTSVPMGSTGG--QVTGQTTAPPSEVRTTIRVEESTLPSRSTDRTPPSESPETPTT 7464
            .:||:  |.||::...:|..  .:||.||...|...|                       ||.|.
 Frog  3892 NTVTISTEATTNIGTATTAAAITITGTTTTTGSTANT-----------------------ETTTN 3933

  Fly  7465 LPSDFTTRPHSDQTTESSRDVPTTQPFESSTPRPVTLEIAVPPVTSETTTNVPIGSTGGQVTGQT 7529
            ..:..||...:..||       ||.|         |:.||    ..:||||||           |
 Frog  3934 TDAATTTSGITLITT-------TTGP---------TITIA----AEKTTTNVP-----------T 3967

  Fly  7530 TATPSEVRTTIGVEESTLPSRSTDRTTPSESPETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFE 7594
            ||.    ..||..|.:.:.|.||..||.|       |..::.||   :..||  |.:||
 Frog  3968 TAN----TVTINTEATAITSTSTTTTTDS-------TANTEITT---TGATT--TTNVP------ 4010

  Fly  7595 ASTPSPASLETTVPSVTLETTTNVPIGSTGGQVTGQTTATPSEVRTTIGVEESTLPSRSTDRTTP 7659
                      ||..:||:.|...   .:|.|..|..|.||.:...||.|...||   .||  :.|
 Frog  4011 ----------TTTNTVTISTGAT---ATTTGAKTTNTGATTNTYTTTTGAITST---GST--SIP 4057

  Fly  7660 SESPETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFEASTPRPVTLETAVPSVTSETTTNVPIGS 7724
            :.:..|||      .|...::....:|...|||      |...||:.|..|:.|:.|.|.   .:
 Frog  4058 NNAISTPT------GTASITNNGIATTATSPTT------TTNTVTINTISPTTTATTATT---SA 4107

  Fly  7725 TVTSE-TTTNVPIGSTGGQVAGQTTAPPSEVRTTIRVEESTLPSRSADRTTPSESPETPTTLPSD 7788
            |.||. ||||..|.:|                     ||:|      :.||.:.:|.|.||....
 Frog  4108 TTTSAITTTNTGIATT---------------------EETT------NTTTITTTPATTTTTAKS 4145

  Fly  7789 FTTRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTGGQLTEQSTSSP 7853
            .||   ...||.:|..:|:     ::|.|.|:..:|.|:|..     :..|...|
 Frog  4146 TTT---GTITTTTTTIIPS-----STTISTANSSSTFPAVNL-----LSYGKDAG---------- 4187

  Fly  7854 SEVRTTIRVEESTLPSRSTDRTFPSESPEKPTTLPSDFTTRPHLEQTTESTRDVLTTRPFETSTP 7918
                      ::....|:.|.|.|...|:    |...|..:.|..........::    |..|..
 Frog  4188 ----------DTEFVKRTVDFTSPLFQPQ----LGFPFGNKLHTNIYYTDNGQII----FPASQN 4234

  Fly  7919 SPVSLETTVPSVTSETSTNVPIGSTGGQVTEQTTAPPSVRTT--ETIVKSTHPAVSPDTTIPSEI 7981
            ...|.  |.|.|...|| |.|:... ....:......:|.||  :...|::..|.|..|....|.
 Frog  4235 DIFSY--TNPPVGGFTS-NYPVAMI-AVFWDDADFSKNVGTTYFQEYTKNSVSAASNSTFQVVED 4295

  Fly  7982 PATRVPLESTTRLYTDQTIPPGSTDRTTSSERPDESTRLTSEESTETTRPVPTVSPRDALETTVT 8046
            ...|....|    ||.|.|                 .::|.|.:.    |.|.     |..:|.|
 Frog  4296 MVRRYVNAS----YTAQWI-----------------LKITWENAP----PYPA-----AAFSTQT 4330

  Fly  8047 SLITETTKTTSG-----------GTPRGQVTERTTKSVSELTTG------RSSDVV----TERTM 8090
            :.. :...||.|           |.....|:.|....|...::|      ::.|::    :||..
 Frog  4331 NTY-QAVLTTDGYISYVLMLYKDGAMNWNVSSRVANVVMGYSSGNGDNFYKNDDLMKRPPSERYR 4394

  Fly  8091 PSNISSTTT-------VFN-NSEPVSDNLPTTIS-ITVTDSPTT-----VPVPTCKTDYDCLDEQ 8141
            |.|....|:       ::| ||:.||:|..|.:: |....:|:|     |..|
 Frog  4395 PCNYQGLTSANVRGLWIYNLNSQAVSNNRMTCMTWINSQPAPSTWNSGLVSCP------------ 4447

  Fly  8142 TCIGGQCISPCEY-FTNLCTVQNLTICRTLNHTTKCYCDTDDDVNRPDCSMKAEIGC-------- 8197
             |:..|.||...: .|...|..::|:.|                |.....:||.:.|
 Frog  4448 -CLYQQGISDSRFRKTKAGTSGSITMLR----------------NTMPSRLKAGVRCLYLNKKQF 4495

  Fly  8198 -----ASSDECPSQQACINALCVDPCTFNNPCSRNED---CRVF-------NHQPLCSAEHGRTP 8247
                 ..|...||.|..:.....|.|     |::.:|   |.::       |.:...|...|.:.
 Frog  4496 LEGFQERSWTSPSSQHDLELTAYDVC-----CNKLDDPQFCSLYIQKRPEINCRSYRSLSSGSSV 4555

  Fly  8248 GCEHCPPGANCDPTTGA--------CIKANVTITTITTKNSTSTKIPTKPRTTANPNTGVKTTPT 8304
            |..|.   :..|..|..        .:.|..::|::..:..|.             .||
 Frog  4556 GDPHM---STLDGLTYTFNGLDDFILLNATASVTSVILQGRTE-------------QTG------ 4598

  Fly  8305 TTRVTTRNTTTTTTTTTTSSTSTE-----SSTITSATNQTS-------------KNQKPD----- 8346
            |.|.|.........|:.|||...|     :.:||:..|..:             .:..||
 Frog  4599 TARATNFQAFALQYTSDTSSVKVEWYLGTNDSITTYVNGQNVTFGYSEDMDTMINDSNPDVFLSM 4663

  Fly  8347 --TESTT---SHTDATRRYRDGENNITDTPTPRPTIQTTTLRGE--GVMG--DSQRRSTTTPKMK 8402
              :.|.|   |.|.:...|....|.||:.|        :...|:  |::|  ||
 Frog  4664 NTSVSATLGGSITVSVSAYYGILNAITNLP--------SEFFGQTRGLLGVWDS----------- 4709

  Fly  8403 TTRLDTSNEVPDTTSPWPIELPTTEGTTTEVYNTMFAPVVNTTDTSLI-NPCTVDTNCAPNEHCK 8466
              .:....::|:.||      .:|..:..::||  :..:...|:.:|. .|.|...|....:...
 Frog  4710 --NMSNDFQMPNGTS------ISTNSSDEDIYN--YGMLWKVTEGNLFTEPKTQRPNNGTFKPLF 4764

  Fly  8467 LGHCRKKEPPGSPKTPEPCQSNNDCIESEACYMGLCQDPCEFAKICAATAKCTAKSHRPVCTC-P 8530
            |...  |...|..:....||:|.:||     |..|..:..:.| :....|....::.:.:... |
 Frog  4765 LKEL--KNSNGYGQLSATCQNNLECI-----YDALVTNNTDLA-LATRQAVVEFQATKAILNAIP 4821

  Fly  8531 QGHEGNPMVKCVTTQT-----------------------------SIECTDDSDCGVTEACINQL 8566
            ....||..::....||                             |:..|..|..|.|...|...
 Frog  4822 PYISGNNTIQAFMKQTVTVQYTSNGTNITFAADLPYQDVNISSNGSLTWTPTSTEGFTLQLIATD 4886

  Fly  8567 CQH----------PCDVH--DPC---ATNAVCINSNHAADCSCADGFQGNGFVGCQPAR---SHV 8613
            .|:          .|:.|  :.|   .|..|...|...|.|||:|.:.|   ..||.|.   :..
 Frog  4887 SQNLSSVLKLMFVVCNCHLANECNYNQTTTVNATSLSIASCSCSDNYSG---TFCQTAPNLCTQG 4948

  Fly  8614 CQYNEDCPPTKLC---------DRLNRRCINPCQ-EDSCGENAECIPVNHGTECRCLPGFLGNAY 8668
            |..|..|.|:..|         |.|:...::.|. .::|..||.|:..|....|.|..|:.||.:
 Frog  4949 CYTNVSCDPSAGCGKCPAGLTGDGLHCNAVDVCALPNNCSINATCVNTNQSYSCNCNTGYTGNGF 5013

  Fly  8669 VQCLPSQGCRSDSECDSSQACINGKCSSPCQCGAYALCDVVNHRGVCKCPPGYNGNPKVGCSPPQ 8733
             .|:....|.:.:.|.|:|.|.|.:       |:|.          |.|..||.||..| |:  .
 Frog  5014 -SCVDINECANANICTSNQTCENTE-------GSYK----------CVCKNGYIGNGTV-CT--Y 5057

  Fly  8734 DPCDPNPCGLNALCELDNGN--PICYCPKGLTGNPFKNCIPEGD--------ECTP--------N 8780
            |.|:.:.|.....|.....|  ..|.|.....|.   .|....|        ..||        |
 Frog  5058 DACESSYCFNGGTCRRQGTNWAQTCSCKSAFNGG---RCETPKDNFPAQLITSVTPKRTVRIFFN 5119

  Fly  8781 PCGPNSGCRRVGGNPVCF----CLPEYEGQPPSIPCELPSNPCDPSPC--GPNTQCSV------- 8832
            |.||.:. ....||...:    ..|:|.|.         ||...||..  |.|:...:
 Frog  5120 PGGPINE-NEANGNVSQYINNSSFPQYIGL---------SNFTAPSNASNGKNSLAQITAEFMYV 5174

  Fly  8833 --------LSNGFSKCTCLPNYVESPN-TIRGCVEPINPCDPNPCGTG-----------AICDSS 8877
                    |:|...|  .:...:.:.| |.|...:.|.    |...:|           ..||:.
 Frog  5175 ADRTVFDYLNNNLVK--KIQQTLHTTNSTSRAATQSIY----NDVESGNYLTLDQMRQMLFCDAG 5233

  Fly  8878 RHPVCYCPDNKIGNPFRLCDKPAVTIELCQPGPCGRNAECYVAGNREECYCRS 8930
            .:...|..|..:     .|....|       |.|..:.:|.:..|:..|.|.|
 Frog  5234 EYSGAYTVDTNL-----TCVSNCV-------GYCQNDGQCTLLFNKTFCNCTS 5274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpy	NP_001260032.1	EGF_3	137..166	CDD:463759
		EGF_CA	212..247	CDD:238011
		EGF_CA	255..>286	CDD:214542
		EGF_CA	298..331	CDD:238011
		EGF_CA	338..373	CDD:238011
		EGF_CA	413..456	CDD:238011
		EGF_CA	457..490	CDD:238011
		EGF_CA	497..>529	CDD:214542
		EGF_CA	580..>612	CDD:214542
		EGF_3	676..702	CDD:463759
		EGF_CA	1022..1056	CDD:214542
		EGF_CA	2227..2260	CDD:238011	10/32 (31%)
		EGF_CA	2393..>2422	CDD:214542	13/28 (46%)
		Herpes_BLLF1	<4032..4489	CDD:282904	92/456 (20%)
		Herpes_BLLF1	<4334..4797	CDD:282904	109/466 (23%)
		PHA03255	4845..>5021	CDD:165513	38/175 (22%)
		DUF5585	4959..5356	CDD:465521	90/396 (23%)
		PHA03247	<5170..5799	CDD:223021	133/628 (21%)
		PRK12495	<5749..5877	CDD:183558	29/127 (23%)
		PHA03247	<5865..6485	CDD:223021	129/619 (21%)
		Chi1	6385..>6609	CDD:442692	35/223 (16%)
		Herpes_BLLF1	<6607..7102	CDD:282904	115/497 (23%)
		Herpes_BLLF1	<7027..7490	CDD:282904	113/466 (24%)
		DUF5585	7550..7954	CDD:465521	98/404 (24%)
		DUF5585	7881..>8130	CDD:465521	60/285 (21%)
		Atrophin-1	18652..>19081	CDD:460830
		PHA03247	<18873..19514	CDD:223021
		ZP	22576..22811	CDD:214579
muc4	XP_031757776.1	Herpes_BLLF1	<53..520	CDD:282904	16/79 (20%)
		EGF_CA	555..586	CDD:214542	13/36 (36%)
		EGF_CA	598..631	CDD:238011	14/71 (20%)
		EGF_CA	634..668	CDD:238011	9/39 (23%)
		EGF_CA	671..707	CDD:238011	15/39 (38%)
		EGF_CA	710..745	CDD:238011	14/108 (13%)
		EGF_CA	748..782	CDD:238011	9/58 (16%)
		EGF_3	789..824	CDD:463759	11/86 (13%)
		NIDO	907..1071	CDD:470642	33/206 (16%)
		AMOP	1083..1224	CDD:470667	30/178 (17%)
		VWD	1232..1406	CDD:214566	35/188 (19%)
		EGF_CA	1686..1727	CDD:214542	12/55 (22%)
		EGF_CA	1728..1763	CDD:238011	11/38 (29%)
		EGF_CA	1771..1807	CDD:238011	8/52 (15%)
		EGF_CA	1808..1845	CDD:238011	8/78 (10%)
		EGF_3	1850..1885	CDD:463759	9/44 (20%)
		EGF_CA	1887..1921	CDD:214542	12/64 (19%)
		EGF_CA	1928..1968	CDD:214542	13/44 (30%)
		EGF_3	1973..2009	CDD:463759	11/41 (27%)
		NIDO	4258..4412	CDD:470642	35/184 (19%)
		AMOP	4421..4538	CDD:470667	28/150 (19%)
		VWD	4556..4721	CDD:459671	37/207 (18%)
		EGF_3	4984..5015	CDD:463759	10/31 (32%)
		EGF_CA	5017..5056	CDD:214542	15/56 (27%)