DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpy and fbn3

DIOPT Version :9

Sequence 1:	NP_001260032.1	Gene:	dpy / 318824	FlyBaseID:	FBgn0053196	Length:	22949	Species:	Drosophila melanogaster
Sequence 2:	NP_001120896.2	Gene:	fbn3 / 100151721	XenbaseID:	XB-GENE-1217676	Length:	2867	Species:	Xenopus tropicalis

Alignment Length:	3226	Identity:	801/3226 - (24%)
Similarity:	1078/3226 - (33%)	Gaps:	1078/3226 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 CDGTQDCFLGADELSK----------ELKCTN--DCDKD---------GTKCTHGACLNGV---- 113
            |.....|.....:||.          .::|.|  .|::|         ||.|....|.||.
Frog    97 CSRPNMCTCSNGQLSTNCGAGIVMNCNVRCMNGGSCNEDSCTCQKGYTGTHCGQPICENGCQNGG 161

  Fly   114 -------CHCNDGYGGCNCVDKDENECKQRPCDVFAH--------------CTNTLGSFT----- 152
                   |.|..|:.|..|    |.:.:..||  |..              ||.||...|
Frog   162 RCIGPNRCACVYGFTGPQC----ERDYRTGPC--FTQISNQMCQGQLSGIVCTKTLCCATIGRAW 220

  Fly   153 ------CTCFPGYRGNGF-------HCEDIDECQDPAIAARCVENAECCNLPAHFLCKCKDGY-E 203
                  |...|.....||       .|:|:||||  ||...| :...|.|....:.|||..|: :
Frog   221 GHPCEMCPAQPNPCRRGFIPNIRTGACQDVDECQ--AIPGLC-QGGTCINTVGSYECKCPAGHKQ 282

  Fly   204 GDGEVLCTDVDECRNPENCGPNALCTNTPGNYTCSCPDGYVGNNPYREGCQDVDE---------- 258
            .:....|.|:|||....|......||||.|:|.|.||.|:..:   |:|.:.:|:
Frog   283 SETSQKCEDIDECSTIPNVCDGGECTNTAGSYVCVCPRGFTTS---RDGSRCIDQRVGSCFSALI 344

  Fly   259 ---CS------------------------YPNVC------------------------------- 265
               |:                        .|.:|
Frog   345 GGRCAGELPGQFTKAHCCCESGRCWAIGQIPEMCPVRGSDAFRRLCIEGLPLGPGFGPEVGPGDM 409

  Fly   266 ---------------GPGA------------------------IC---TNL---------EGSYR 279
                           |||.                        ||   |||         ..|||
Frog   410 RPGETGGNGLRPVRPGPGGPNGPELLPGLSTGIGTATLNQTGDICKLFTNLCQNGRCIPTPASYR 474

  Fly   280 CDCPPGYDGDGRSESGCVDQDECARTPCGRNADCLNTDGSFRCLCPDGYSGDP-MNGCEDVDECA 343
            |:|..||..|.|.|  |:|.|||:.:|| .:.||:||.||:.|.|.:||..:| ...|.|:|||.
Frog   475 CECNMGYKQDSRLE--CIDVDECSSSPC-IHGDCVNTPGSYHCRCHEGYQSNPTKQACIDIDECI 536

  Fly   344 TNNPCGLGAECVNLGGSFQCRCPSGFVLEHDPHADQLPQPLNTQQLGYGPGATDIAPYQRTSGAG 408
            .|........|||..|||||.|.:||                                 .|:..|
Frog   537 MNGVMCRNGRCVNTEGSFQCICNAGF---------------------------------ETTPDG 568

  Fly   409 LACLDIDECNQPDGVAKCGTNAKCINFPGSYRCLCPSGF----QGQGYLHCENINECQDNPCGEN 469
            ..|:|.|||    .......|..|||..||::|:|..||    .|:   :|.:::|||......|
Frog   569 KNCVDHDEC----ATTNMCLNGMCINEDGSFKCICKPGFVLAPNGR---YCVDVDECQTPGICMN 626

  Fly   470 AICTDTVGSFVCTCKPDYT-GDPFRGCVDIDECTALDKPCG---QHAVCENTVPG----YNCKC- 525
            ..|.:|.|||.|.|....| |...|.|||    |.:...|.   :...|....||    ..|.|
Frog   627 GRCINTEGSFRCECLGGLTIGIDGRVCVD----THMRSTCYGAIKKGTCARPFPGAVTKSECCCA 687

  Fly   526 -PQGYDGKP-DPKVACEQVDVNILCSSNF----------DCTNNAECIEN----------QCFCL 568
             |....|:| .|..|....:...||||..          :|..|:|...|          :|.|.
Frog   688 SPDHGFGEPCQPCPAKNSAEFQALCSSGIGITADGRDINECALNSEICPNGICENLRGSYRCICN 752

  Fly   569 DGFE--PIGSSCVDIDECRTHAEVCGPHAQCLNTPGSYGCECEAGYVGSPPRMACKQPCEDV-RC 630
            .|:|  ..|.:|||:|||..:..:| .:..|.||||||.|.|..|||..    ...:.|||: .|
Frog   753 LGYESDASGKNCVDVDECAVNRLLC-DNGLCRNTPGSYTCTCPKGYVFK----IDSETCEDINEC 812

  Fly   631 GA----HAYCKPDQNEAYCVCEDGWTYNPSDVAAGCVDI-----------DECDVMHGPFGSCGQ 680
            .:    :..|:.:.....|.|..|...:.:...  |||.           ..|:|...  |:..:
Frog   813 ASNPCVNGVCRNNAGSFVCECSFGSKLDSTGTI--CVDSMKGTCWLNIQDGRCEVNIN--GATLK 873

  Fly   681 NATCT--NSAGGFTC-------ACPPGFSGDPHSKCVDVDECRTGASKCGAGAECVNVPGGGYTC 736
            :..|.  .:|.|..|       |||.|:|......|.||:||......|..| .|||. .|.:.|
Frog   874 SECCATLGAAWGSPCERCEIDPACPRGYSRKKGVACEDVNECEVFPGVCPNG-RCVNT-AGSFKC 936

  Fly   737 RCP-GNTIADPDPSVR-CVPI--------------------------VSCSAN-------EDC-- 764
            .|| |.|:   |.|.| ||.:                          ..||..       |:|
Frog   937 ECPEGLTL---DGSGRNCVDVRVEQCYMKWDEDECTAQLPGKYRMDMCCCSVGAAWGIDCEECPK 998

  Fly   765 PGNSICDATKRCLCPE-PNIGN------------DCRHPCEALN--CGAHAQCMLANGQAQCLCA 814
            ||:   |..| .|||. |...|            |. :.|:..|  | .|..|..:.|..:|:|.
Frog   999 PGS---DEFK-ALCPRGPGFANRGDVLSGRPFYKDV-NECKVFNSLC-THGTCRNSIGSFRCVCD 1057

  Fly   815 PGYTGNSALAGGCNDIDECRANP--CAEKAICSNTAGGYLCQCPGGSSGDPYREGCITSKTVGCS 877
            .|: ...|....|.||||||.:|  |.. ..|.||.|.:.|:|     .|.|..|.:..|  .|.
Frog  1058 SGF-ALDAEERNCTDIDECRISPDLCGH-GTCVNTPGSFDCEC-----FDGYESGFMMMK--NCM 1113

  Fly   878 DANPC------ATGETCVQDSYTGNSVCICRQGYERNSENGQCQDVDECSVQRGKPACGLNALCK 936
            |.:.|      ..|.||:...  |:..|||..|:|..||...|.|::|||:...  .| .|..|.
Frog  1114 DIDECERDPLLCRGGTCINTD--GSFECICPPGHELTSEGNACVDINECSLSDN--LC-RNGRCI 1173

  Fly   937 NLPGSYECRCPQGHNGNPFIMCEICNTPECQCQSPYKLVGNSCVLSGCSSGQACPSGAECISIAG 1001
            |:.|:|:|.|..|....|                               ..|.|....||..:.|
Frog  1174 NMIGTYQCSCDSGFQSTP-------------------------------DRQGCVDIDECTIMNG 1207

  Fly  1002 GV---------SY-CACPKGYQTQPD-GSCVDVDECEERGAQLCAFGAQCVNKPGSYSCHCPEGY 1055
            |.         || |:|.:||...|| .||.|:||||: ...:|. |.||.|.||.|.|.|.:|:
Frog  1208 GCDTHCTNSEGSYECSCSEGYALMPDQRSCADIDECED-NPDICD-GGQCTNIPGEYRCLCFDGF 1270

  Fly  1056 QGDAYNGLCALAQRKCAADRECAANEKCIQPGECV---------CPPPYFLDP-----QDNNKCK 1106
                   :.:|..:.|....||..|......|||.         |...||:..     .|.::|:
Frog  1271 -------MASLDMKTCIDVNECDLNPNICLHGECENTKGSFICHCQLGYFVKKGTTGCTDIDECE 1328

  Fly  1107 SPCERFPCGINAKCTPSDPP---QCMCEAGFKGDPLLGCTDEDECS---HLPCAYGAYCVNKKGG 1165
            .....  |.::|.|.  :.|   :|.|:.|:.||. |.|.|.|||:   | .|...|.|||..|.
Frog  1329 VGAHN--CDVHASCL--NVPGSFKCQCQTGWVGDG-LNCVDLDECTTEDH-KCNANANCVNTPGS 1387

  Fly  1166 YQCVCPKDYTGDPYKSGCIFESGTPKSKCLSNDDCASNLACLEGSCVSPCSSLLCGSNAYCETEQ 1230
            |:|.|.:.:.||    |.|         |...|:||.|:.             || .|.:|....
Frog  1388 YRCACNEGFNGD----GFI---------CSDVDECADNVN-------------LC-ENGHCLNAP 1425

  Fly  1231 HAGWCRCRVGYVKNGDGDCVSQCQDV-------ICGDGALCIPTSEGPTCKCPQG-QLGNPFPGG 1287
            ....|.|.:|:....|.   ..|||:       ||..|. |........|.|..| :|..  .||
Frog  1426 GGYRCECEMGFTPTEDS---KACQDIDECTFQNICVFGT-CQNLPGMFRCICDDGYELDR--SGG 1484

  Fly  1288 SCSTDQCSAARPCGERQICINGRCKERCEGVVC-----------GIGATCDRNNGKCICEPNFVG 1341
            :| ||    ...|.:...||||.|.......:|           |:|.. |...|.|..|....|
Frog  1485 NC-TD----VNECADPVNCINGLCVNTPGNYLCNCPQDFELNPTGVGCV-DTRVGNCFLETQPRG 1543

  Fly  1342 NPDLICMPPIEQAKCSPGCGENAHCEYGLGQSR--CACNPG-TFGNPYEGCGAQSKNVCQPNSCG 1403
            :..|.|                 ..|.|:|.:|  |.|:.| .:|||.|.|
Frog  1544 DGGLSC-----------------SAEIGVGVTRASCCCSLGRAWGNPCEFC-------------- 1577

  Fly  1404 PNAECRAVGNHISCLCP--QGFSGNPY-IGCQDVDECANKPCGL--NAACLNRAGGFECLCLSGH 1463
            |.|.    ......|||  :||..||. :..:|:|||...| ||  ...|:|..|.|:|.|.:|:
Frog  1578 PFAN----STEYKTLCPGGEGFRPNPITVILEDIDECQELP-GLCQGGNCVNTFGSFQCECPAGY 1637

  Fly  1464 AGNPYSSCQPIESKFCQDANKCQCNERVECPEGYSCQKGQCKNLCSQASCGPRAICDAGN--CIC 1526
            ..|.       |::.|:|.::|..:..:       |..|.|.|             ..||  |:|
Frog  1638 YLNE-------ETRICEDIDECSAHIGI-------CGPGTCYN-------------TLGNYTCVC 1675

  Fly  1527 PMGYIGDPHDQVHGCSIRGQCGNDADCLHSEICFQLGKGLRKCVDACSKIQCGPNALCVSEDHRS 1591
            |..|:     ||:|       ||:...:...:|:      |...|.|.      |.|. |...:.
Frog  1676 PPEYM-----QVNG-------GNNCMDMRKSVCY------RNYNDTCE------NELS-SNMTKK 1715

  Fly  1592 SCICSDGFFGNPSNLQVGCQPERTVPEEEDKCKSDQDCSRGY------GCQASVNGIKECINLCS 1650
            .|.||.. .|...|......|....||....|.:.   :.|:      |....::...|...:||
Frog  1716 MCCCSYN-IGKAWNKPCEPCPSPATPEYIFLCGNQ---APGFIIDIRTGKPMDIDECSEIPAICS 1776

  Fly  1651 NVVCGPNELCKINPAGHAICNCAESYVWNPVVSSCEKPSLPDCTSDANCPDASACRPDVLGVLKC 1715
            |.||       ||..|...|.|...:.:|.::..||  .:.:|:|..|
Frog  1777 NGVC-------INQIGSFRCECPMGFSYNNILLICE--DIDECSSGEN----------------- 1815

  Fly  1716 VAICDAFTCPANSVCVARQHQGRCDCLNGFVGNPN----DRNGCQPAQKHHCRNHAECQESEA-- 1774
                   .|..|:.|:......||:|.:|:..:|:    .||.||.. .:.| :|..|.::|.
Frog  1816 -------LCQRNADCINIPGSYRCECSSGYKLSPSGACVGRNECQEI-PNVC-SHGTCMDTEGSY 1871

  Fly  1775 -CI-----KDESTQTLGCR--PACDTVKCGPRAVCVTNNHQAQCQCPPGPFAGDPYDPFNGCQSV 1831
             |:     |....||: |.  ..||...|| ...|........|.|.||               .
Frog  1872 ICVCHNGFKASGDQTM-CMDIDECDRQPCG-NGTCKNTVGSYNCLCFPG---------------F 1919

  Fly  1832 PCVYNHDCPPSQMCNRMTHTCFDVCDEESCGDNAICLAEDHRAVCQCPPGFKGDP-----LPEVA 1891
            ...:|:||.....|..:..   .||....|.:|.....      |.|..|::..|     :....
Frog  1920 ELTHNNDCMDIDECYSLVG---QVCRNGQCINNVGSFQ------CLCQEGYEITPDGKNCMDINE 1975

  Fly  1892 CTK-QGGCAAGTCHPSAICEVTPEGPV-CKCPPLFVGDAKSGGCRPDGQC---PNGDADCPANTI 1951
            ||. .|.|:.|||.       ..||.. |.|||.|  :.::..|....:|   ||         |
Frog  1976 CTSLPGTCSPGTCQ-------NLEGSFRCICPPGF--EVQNDNCIDINECDEEPN---------I 2022

  Fly  1952 CAGGVCQNPCDNACGSNAECKVINRKPVCSCPLRFQPISDTAKDGCARTISKCLTDVDCGGALCY 2016
            |..|.    |.|..||..          |.||..| .:||..:.......|.|.|..|
Frog  2023 CLFGT----CTNTPGSFQ----------CVCPPGF-VLSDNGRRCFDTRQSFCFTRFD------- 2065

  Fly  2017 NGQC-----------RIACRNSQDCSDGESCLKNVCVVACLDHSQCASGLACVEGHCTI-GCRSN 2069
            ||:|           |..|........|:.|      ..|......|....|..||.:| |....
Frog  2066 NGKCSVPKAFNTTKARCCCSKMPGEGWGDPC------ELCPQEGSVAFQELCPYGHGSIPGMGDT 2124

  Fly  2070 KECKQDQSCIENKCLNPCQSANSCGPNALCSIDQHHSQCSCPEGFEGNPTPEQGCVRVPAPCLAS 2134
            :|           .:|.|..:.....|.:|.......:|.||.|:..:.|
Frog  2125 RE-----------DVNECSESPGICVNGVCINTDGSFRCECPFGYNLDYT--------------- 2163

  Fly  2135 NQCPSGHMCIGNQCNLPCTKTASCAVGERCYQQVCRKVCYTSNNCLAGEICNSDRTCQPG----C 2195
                          .:.|..|..|::|..|....|       :|.:.|..|..|...:||    |
Frog  2164 --------------GVNCVDTDECSIGNPCGNGTC-------SNVVGGFECTCDEGFEPGPMMTC 2207

  Fly  2196 DSDADCPPTELCL--------TGKCKCATGFI--GTPFGCSDIDECTE--QPCHA-SARCENLPG 2247
            :...:|....||.        :.:|.|.:|:.  .....|.|:|||.|  ..|.: ...|:||.|
Frog  2208 EDINECTNPLLCAFRCINTYGSYECTCPSGYTLREDRRMCKDLDECAEGLHDCESRGMMCKNLIG 2272

  Fly  2248 TYRCVCPEGTV--GDGYSQPGCSQPRQCH-KPDDCANNLACIH---------------------- 2287
            |:.|:||.|..  .||   .||....:|. ||..|.|. .|::
Frog  2273 TFMCICPPGMQRRPDG---EGCMDENECRTKPGICVNG-RCVNTVGSYKCDCNEGFQVSSSGTEC 2333

  Fly  2288 -----GKCTDPCLHTVCGINANCQSEGHEALCSCPAGFLGDPND------TGVGCFKVECIDHVD 2341
                 |.|....|.|:|.:::..::...::.|.|.:| .|..|.      .|.|.||..|.....
Frog  2334 VDTRQGFCFTEVLQTMCQLSSTNRNMVTKSECCCNSG-RGWGNQCEICPLPGTGAFKKMCPHGPG 2397

  Fly  2342 CAGDRACDAETNRCIKPCDL--TSCGKGNCQVRDHKATCACYEGY--QLVNDVCEDINECLSQPC 2402
            .|.|       .|.|..|.:  ..|..|.|........|.|..||  .:....|.|::||...|.
Frog  2398 FATD-------GRDIDECKVLPNLCKNGQCINTIGSFRCHCKLGYTTDITGTTCVDLDECAQSPK 2455

  Fly  2403 HSTAFCNNLPGSYSCQCPEGLIGDPLQAGCRDPNECLSDADCPASASCQNSRCRSPCERQNACGL 2467
            .....|.|..|||.|.||.|.|.......|:|.:||          |.:...|:..|  .|..|
Frog  2456 PCNFICKNTEGSYQCSCPRGYILQEDGKTCKDLDEC----------STKQHNCQFLC--VNTIG- 2507

  Fly  2468 NANCQAQAHQAICTCPLNSRGDPTIECVHIECADNDDCSGEKACLDSKCIDPCSLPNACGALARC 2532
            :.||:         ||      |........|.||::||              |.|:.||:...|
Frog  2508 SFNCK---------CP------PGFTQHQSSCIDNNECS--------------SQPSLCGSRGVC 2543

  Fly  2533 SVQNHIG--VCSCEAGSTGDAKLGCVQLQYCQQDGQCAQGSICSHGICSPLCSTNRDCISEQLCL 2595
              ||:.|  .|.|:.|.:.|:. |    ..|:...:|.....|.||
Frog  2544 --QNNPGSFTCECQKGFSLDSS-G----SNCEDVDECDGNHRCQHG------------------- 2582

  Fly  2596 QGVCQGTCKS-NSSCPQ--FQFCSNNICTKELECRSDSECGEDETCLSDAYGRAKCESVCLGRAA 2657
               ||..... ...|||  .|....|.|..|.||.|.|.||
Frog  2583 ---CQNVLGGFRCGCPQGYVQHYQWNQCVDENECTSQSTCG------------------------ 2620

  Fly  2658 CGRNAECVARSHAPDCLCKEGF-FGDAKSGCRKIECTSDDDCSNDKSCDNHMCKIACLIGQPCGE 2721
               :|.|.....:..|:|..|| |..:..||:.:     |:||:.                  |.
Frog  2621 ---SASCYNTLGSFKCVCPSGFDFDQSFGGCQDV-----DECSSG------------------GG 2659

  Fly  2722 NALCTTEHHQQVCHCQPGFSGDPRVRCDVIDFCRDAPCGPGARCRNARGSYKCTCPPG------- 2779
            |                                   ||..|  |.|..|.|.|.||.|
Frog  2660 N-----------------------------------PCSYG--CSNTDGGYLCGCPGGYFRAGQG 2687

  Fly  2780 --LVGDPYNEGCRSSVECETNED---CPPHAACTKTNGVAK 2815
              :.|..:.:|.......|.:|:   .|.:....|.||..|
Frog  2688 HCVTGMGFGKGSYLQAPVEEDEENVLSPENCYECKINGYPK 2728

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpy	NP_001260032.1	EGF_3	137..166	CDD:289699	12/60 (20%)
		EGF_CA	212..247	CDD:238011	15/34 (44%)
		EGF_CA	255..>286	CDD:214542	17/149 (11%)
		EGF_CA	298..331	CDD:238011	16/32 (50%)
		EGF_CA	338..373	CDD:238011	16/34 (47%)
		EGF_CA	413..456	CDD:238011	15/46 (33%)
		EGF_CA	457..490	CDD:238011	12/33 (36%)
		EGF_CA	497..>529	CDD:214542	9/40 (23%)
		EGF_CA	580..>612	CDD:214542	14/31 (45%)
		EGF_3	676..702	CDD:289699	10/34 (29%)
		EGF_CA	1022..1056	CDD:214542	16/33 (48%)
		EGF_CA	2227..2260	CDD:238011	15/37 (41%)
		EGF_CA	2393..>2422	CDD:214542	12/28 (43%)
		DUF4758	4088..4282	CDD:292572
		DUF4696	4127..4678	CDD:292395
		DUF4758	4275..4448	CDD:292572
		DUF4758	4377..4574	CDD:292572
		DUF4758	4581..4754	CDD:292572
		DUF4758	4683..4847	CDD:292572
		DUF4758	4785..4964	CDD:292572
		DUF4696	4841..5385	CDD:292395
		DUF4758	4887..5098	CDD:292572
		DUF4758	5193..5371	CDD:292572
		DUF4758	5294..5487	CDD:292572
		DUF4758	5445..5650	CDD:292572
		DUF4758	5700..5877	CDD:292572
		DUF4696	5756..6396	CDD:292395
		DUF4758	5802..5979	CDD:292572
		DUF4758	5964..6171	CDD:292572
		DUF4758	6181..6360	CDD:292572
		DUF4696	6339..6999	CDD:292395
		DUF4758	6662..6839	CDD:292572
		DUF4758	6764..6941	CDD:292572
		DUF4758	6866..7045	CDD:292572
		DUF4758	6968..7179	CDD:292572
		DUF4696	7024..7569	CDD:292395
		DUF4758	7172..7383	CDD:292572
		DUF4696	7330..7964	CDD:292395
		DUF4758	7400..7587	CDD:292572
		DUF4758	7538..7707	CDD:292572
		DUF4758	7798..7979	CDD:292572
		DUF4758	7946..8126	CDD:292572
		YppG	18767..>18832	CDD:290883
		Med25_SD1	18795..18955	CDD:288132
		MISS	19026..19258	CDD:292450
		ZP	22576..22811	CDD:214579
		Zona_pellucida	<22714..22810	CDD:278526
fbn3	NP_001120896.2	Fibrillin_U_N	49..85	CDD:375622
		TB	197..>231	CDD:366245	6/33 (18%)
		EGF_CA	249..>279	CDD:214542	13/32 (41%)
		EGF_CA	291..331	CDD:311536	17/42 (40%)
		TB	347..390	CDD:366245	3/42 (7%)
		EGF_CA	491..525	CDD:214542	16/34 (47%)
		EGF_CA	531..572	CDD:214542	18/73 (25%)
		EGF_CA	573..613	CDD:214542	15/46 (33%)
		EGF_CA	614..647	CDD:214542	12/32 (38%)
		TB	670..712	CDD:366245	10/41 (24%)
		EGF_CA	724..765	CDD:214542	9/40 (23%)
		vWFA	<761..805	CDD:381780	20/48 (42%)
		TB	862..>895	CDD:366245	7/34 (21%)
		EGF_CA	911..951	CDD:389777	18/44 (41%)
		TB	967..1009	CDD:366245	9/45 (20%)
		EGF_CA	1071..1105	CDD:214542	16/39 (41%)
		EGF_CA	1114..1146	CDD:214542	10/33 (30%)
		EGF_CA	1156..1189	CDD:214542	13/35 (37%)
		FXa_inhibition	1202..1237	CDD:373209	11/34 (32%)
		EGF_3	1327..1362	CDD:372403	11/39 (28%)
		EGF_3	1368..1403	CDD:372403	15/48 (31%)
		EGF_CA	1405..1445	CDD:389777	12/56 (21%)
		EGF_CA	1447..1487	CDD:214542	12/43 (28%)
		TB	1549..1590	CDD:366245	16/75 (21%)
		EGF_CA	1606..1638	CDD:214542	14/32 (44%)
		cEGF	1628..1651	CDD:372248	8/29 (28%)
		TB	1703..1747	CDD:366245	12/51 (24%)
		EGF_CA	1764..1796	CDD:214542	11/38 (29%)
		EGF_CA	1806..>1838	CDD:214542	9/55 (16%)
		vWFA	<1846..1885	CDD:381780	10/40 (25%)
		EGF_CA	1890..1924	CDD:214542	9/49 (18%)
		EGF_CA	1929..1970	CDD:311536	9/49 (18%)
		EGF_CA	1972..2004	CDD:214542	14/40 (35%)
		EGF_CA	2012..2052	CDD:214542	16/63 (25%)
		TB	2069..2112	CDD:366245	7/48 (15%)
		EGF_CA	2127..2168	CDD:214542	9/69 (13%)
		EGF_CA	2169..2208	CDD:214542	11/45 (24%)
		EGF_CA	2209..2241	CDD:238011	6/31 (19%)
		EGF_CA	2249..2291	CDD:389777	17/44 (39%)
		TB	2353..2393	CDD:366245	9/40 (23%)
		EGF_CA	2404..2445	CDD:214542	9/40 (23%)
		vWFA	<2444..2484	CDD:381780	15/39 (38%)
		vWFA	<2482..2518	CDD:381780	14/63 (22%)
		cEGF	2549..2572	CDD:372248	6/27 (22%)
		EGF_CA	2569..>2598	CDD:214542	9/50 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11452
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D4721at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48600
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010