Protein Alignment Aladin and aaas

DIOPT Version :10

• Sequence 1: NP_572557.1
• Gene: Aladin / 31881
• FlyBaseID: FBgn0030122
• Length: 466
• Species: Drosophila melanogaster
• Sequence 2: XP_068079439.1
• Gene: aaas / 378454
• ZFINID: ZDB-GENE-030912-4
• Length: 500
• Species: Danio rerio
• Alignment Length: 486
• Identity: 151/486 - (31%)
• Similarity: 232/486 - (47%)
• Gaps: 64/486 - (13%)

  Fly    17 PDLALRHNHI-----PELERY-PQINLNS-----ELLANPAGQRYYGGQSFVSVNEGVLKRIARS 70
            |.||..|.|.     .||:.. ||::|.|     :.|...:........:|:...:.:.:|.|.:
Zfish    10 PPLAAGHTHTLMEQHNELQASDPQVDLPSPQFTRDTLKGHSRAESSSKSAFLDQRDTLWRRSAGA 74

  Fly    71 FFNGGFWKTLEEARSPETREQAPLIAQAGD--LIA------QFLGLATGLRILPHTQQLSAERIA 127
            :.:.|.:..|::..:  :.::.|.....|.  |:|      .|.|     .:.||....|.|.:|
Zfish    75 WRDAGLYGLLDQITN--SADEVPRCVSVGSSCLLALLRWSSSFHG-----SLFPHLTLSSDEMVA 132

  Fly   128 QFVETRDWLNSDVRYLAWNQHFFCLAVAGVDDVVRIYTKSSSATTATVLKSPSQTQITCMAWRPL 192
            :|.:..||.:|.||..:|:.|....|||.:||.::||...||  ||..||...|..:..:.|:||
Zfish   133 EFSQMLDWSDSAVRSFSWHPHTDKFAVALLDDSIKIYKPHSS--TAPTLKHRCQRSVCALQWKPL 195

  Fly   193 CASEIVIGCRQGLCFWEVD-STLHLGRTNAPSEIFKYPNNLPITSMQWNKDGTQLATASIGDRSI 256
            |.|.:.:.|:..|..|.|| ::|....::..:::..:|.:.||||:.|:..|:.|.:||..|.::
Zfish   196 CGSALAVACQSCLLIWHVDPASLSTRPSSGCAQVLSHPGHSPITSIAWSPTGSLLVSASPVDTAM 260

  Fly   257 IIWQPDTGMMQPLKRLGPPG-SLLKWSPDNDWLFAATVDRVFRVWNCHQQWTTERWVCGPGGYVQ 320
            ::|........||:|:|..| :.|.||||...|.|||...:||||.. :.||.|||.|..|. .|
Zfish   261 MVWDVAAESCVPLRRVGGGGVTFLSWSPDGSRLLAATPSALFRVWET-RMWTCERWPCLKGS-CQ 323

  Fly   321 TACWSPCGRFLLFVSSAEPILYRLQFVQQSLLSSSADEKEILPIADLNACSI---DANRTLVGGP 382
            :|||||.|..||.....|.::|.|.|     ...:...|....:|||:..|.   :.:.| |||.
Zfish   324 SACWSPDGACLLLSIQGERLIYALSF-----SDLTGGPKAATVVADLSETSFPGPEGDLT-VGGE 382

  Fly   383 AQQLAWDPHGNYLVVTFKA-------TNCIAVFRTFIQKFDLQISAAY------YLSGETAAEHP 434
            ...|:|||.|..|.|..|.       .:.||||:|       :.|.|:      ::.||..|| |
Zfish   383 VCSLSWDPRGERLAVLLKGDAQSTDHPSVIAVFKT-------RCSPAFELLPCGFVMGEAGAE-P 439

  Fly   435 SFICFQPLYEDNDRSVLTIAWSSGRIQYYAF 465
            .|:.|.|.::..  ::||:.||.|||.:..|
Zfish   440 RFMQFHPHFQHG--ALLTVCWSDGRITHVPF 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aladin	NP_572557.1	WD40 repeat	137..177	CDD:293791	16/39 (41%)
		WD40	<152..336	CDD:441893	71/185 (38%)
		WD40 repeat	184..227	CDD:293791	11/43 (26%)
		WD40 repeat	235..274	CDD:293791	12/38 (32%)
		WD40 repeat	276..312	CDD:293791	18/36 (50%)
		WD40 repeat	320..357	CDD:293791	13/36 (36%)
		WD40 repeat	364..400	CDD:293791	15/38 (39%)
		WD40 repeat	407..441	CDD:293791	12/39 (31%)
aaas	XP_068079439.1	WD40	<138..396	CDD:441893	96/267 (36%)
		WD40 repeat	147..181	CDD:293791	14/35 (40%)
		WD40 repeat	188..234	CDD:293791	11/45 (24%)
		WD40 repeat	238..274	CDD:293791	11/35 (31%)
		WD40 repeat	282..315	CDD:293791	16/33 (48%)
		WD40 repeat	322..371	CDD:293791	18/53 (34%)