Protein Alignment Cfp1 and cxxc1

DIOPT Version :10

• Sequence 1: NP_572556.1
• Gene: Cfp1 / 31880
• FlyBaseID: FBgn0030121
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: XP_031747257.1
• Gene: cxxc1 / 613066
• XenbaseID: XB-GENE-5910691
• Length: 609
• Species: Xenopus tropicalis
• Alignment Length: 617
• Identity: 214/617 - (34%)
• Similarity: 301/617 - (48%)
• Gaps: 160/617 - (25%)

  Fly    62 YCICRSSDCSRFMIGCDGCEEWYHGDCIGITEKEAKHIKQYYCRRCKKENPELQTIFRLV----- 121
            |||||..|.:.||||||.|.||:||.||.||||.||.|:::||.:|:.::|.|:..:|..
 Frog    25 YCICRKPDINCFMIGCDNCNEWFHGHCINITEKMAKAIREWYCVQCRDKHPHLEIKYRHKKSKER 89

  Fly   122 --ATERAAASNAASTSLNAPGVGPSGAAPAAAPVASATTSQQAPPPTTAAAKRKNSSAREPKMGK 184
              .||:......|.......|             :::::|.:.|         :....|..:|
 Frog    90 ERETEKDENEETAKNEKKKSG-------------STSSSSNKVP---------RQQIKRSARM-- 130

  Fly   185 RCGTCEGC-RRPNCNQCDACR--VRVGH----KPRCIFRTCVVQAA------------------- 223
             ||.||.| |..:|.|||.||  .:.|.    :.:|..|.|.|:|.
 Frog   131 -CGECEACSRTEDCGQCDFCRDMKKFGGPNKIRQKCRLRQCQVRARVSRRAPVSPGAEWPLLSAP 194

  Fly   224 ----------------------------------------------------------------- 223
                                                                             
 Frog   195 VVPGYSILLLQKMLRVKDDDLSLFRDTPEPSSLAGSLSDDDLPLDPELYQELCAGGAFDDHNLPW 259

  Fly   224 -----------TVLKESQATQAGPSRKREKAA------------PKSRNVQVGPRAASPEIFLNP 265
                       :|::: :|.:....::|||.|            .|.|:......:...||   .
 Frog   260 LSDTDDTPFLDSVMRK-RAVKVKHVKRREKKADKKKDEKYKRHKQKQRHKDKTKHSERTEI---R 320

  Fly   266 ELQGIRQCYGPNCCSHARPQSKYCSDKCGFNLATKRIFQVLPQRLQEWNLTPSRAAEETRKHLDN 330
            :...:|||.||:|...||..||||||.||..||..||:::||||:|:|..:|..|.|:.:|.|:.
 Frog   321 DFSSLRQCLGPSCVQPARSSSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPCVAEEQGKKLLER 385

  Fly   331 IRHKQSLVRFALAELEKRSEELNMVVERAKRSSI-----DTLGSQDTADMEDEQSMYCITCGHEI 390
            ||.:|...|..|..:|.|..||..::.:||:..|     ...|..|..|::    ::|::|||.|
 Frog   386 IRREQQQARTKLQNMESRFHELEALISKAKQQQIREDEETNEGDSDDTDLQ----IFCVSCGHPI 446

  Fly   391 HSRTAIKHMEKCFNKYESQASFGSIFKTRMEG-NNMFCDFYNPASKTYCKRLRVLCPEHSKDPKV 454
            :.:.|::|||:|:.|||||.||||::.||:|| ..:|||.|||.||||||||:|||||||:||||
 Frog   447 NPKVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPHSKTYCKRLQVLCPEHSRDPKV 511

  Fly   455 NDTDVCGSPLVNNVFNPTGEFCRAPKKNCFKHYAWEKIRRAEIDLERVRQWLKMDDLMEQERVMR 519
            ...:|||.|:|.:||..||:|||.||:.|.:||.|||:||||:||||||.|.|:|:|.||||.:|
 Frog   512 PADEVCGCPMVKDVFELTGDFCRVPKRKCNRHYCWEKLRRAEVDLERVRLWYKLDELFEQERNVR 576

  Fly   520 QQLTSRANLLGLMLHSTYNHEVMDELVRKQQE 551
            ..:|:||.||.||||.|..|:.:...:|...|
 Frog   577 MAMTNRAGLLALMLHQTIQHDPVTTDLRTHTE 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cfp1	NP_572556.1	PHD_Cfp1	62..107	CDD:277028	28/44 (64%)
		zf-CXXC	178..218	CDD:366873	17/46 (37%)
		CpG_bind_C	298..532	CDD:463514	121/239 (51%)
cxxc1	XP_031747257.1	PHD_Cfp1	25..70	CDD:277028	28/44 (64%)
		zf-CXXC	123..170	CDD:366873	17/49 (35%)
		CpG_bind_C	353..589	CDD:463514	121/239 (51%)