Protein Alignment Cfp1 and cxxc1a

DIOPT Version :10

• Sequence 1: NP_572556.1
• Gene: Cfp1 / 31880
• FlyBaseID: FBgn0030121
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_956893.1
• Gene: cxxc1a / 393571
• ZFINID: ZDB-GENE-040426-1142
• Length: 570
• Species: Danio rerio
• Alignment Length: 589
• Identity: 211/589 - (35%)
• Similarity: 306/589 - (51%)
• Gaps: 115/589 - (19%)

  Fly    45 PERKSKIATILKQEDQAYCICRSSDCSRFMIGCDGCEEWYHGDCIGITEKEAKHIKQYYCRRCKK 109
            |||     |:::.....||:||..|.:.||||||.|.||:|||||.|:||.||.|:.:||.:|:.
Zfish    14 PER-----TLIRGNAPVYCVCRRPDINCFMIGCDSCSEWFHGDCIKISEKTAKTIRVWYCEKCRS 73

  Fly   110 ENPELQTIFR-LVATERAAASNAASTSLNAPGVGPSGAAPAAAPVASATTSQQAPPPTTAAAKRK 173
            ::..|:..:| ..:.|:.|.::...|..:.|.....|                          |:
Zfish    74 KDETLEVKYRPKKSREKEAETDGPDTQPDTPDFKSDG--------------------------RR 112

  Fly   174 NSSAREPKMGKRCGTCEGC-RRPNCNQCDACR--VRVGH----KPRCIFRTCVVQAATVLK---- 227
            .|  |..:..:.||.||.| |..:|..||.|:  .:.|.    :.:|..|.|.|:|..:|:
Zfish   113 GS--RIKRSARMCGECEACLRTEDCGLCDFCKDMKKFGGPNKIRQKCRLRQCEVRARKMLRVKEE 175

  Fly   228 -----ESQATQAGP--------------------------------------------------- 236
                 :|:..|.||
Zfish   176 EYSMSKSRDYQDGPLSEEYSENELELYQQYCAGQYGDNGTGWNSDDDDGSYGESSLRKKAVKVKH 240

  Fly   237 -------SRKREKAAPKSRNVQVGPRAASPEIFLNPELQ------GIRQCYGPNCCSHARPQSKY 288
                   |.|.||...::::.:..|:....:...:.|..      |.|||.||.|...||..|||
Zfish   241 VKRREKRSEKSEKKKEENKSRKHKPKQKHRDRVRHSERAEVRDSGGARQCLGPGCVEAARANSKY 305

  Fly   289 CSDKCGFNLATKRIFQVLPQRLQEWNLTPSRAAEETRKHLDNIRHKQSLVRFALAELEKRSEELN 353
            |||.||..||..||.::||||:|:|..:|..|.|:.:|.|:.||.:|.|.|..|.|:|||..||.
Zfish   306 CSDDCGMKLAANRICEILPQRIQQWQQSPCIAEEQGKKFLERIRREQQLARMRLTEMEKRFHELE 370

  Fly   354 MVVERAKRSSIDTLGSQDTADMEDEQSMYCITCGHEIHSRTAIKHMEKCFNKYESQASFGSIFKT 418
            .::.:||:..:......:..|.:.:..::|::|.|.::.:.|::|||:|:.|||||.||||::.|
Zfish   371 GIIAKAKQQVVQYDEEVNEGDDDTDLQIFCVSCSHSVNPKVALRHMERCYAKYESQTSFGSMYPT 435

  Fly   419 RMEG-NNMFCDFYNPASKTYCKRLRVLCPEHSKDPKVNDTDVCGSPLVNNVFNPTGEFCRAPKKN 482
            |:|| ..:|||.|||.||||||||:|||||||:|||:...:|||.|||.:||.||||:||..|:.
Zfish   436 RIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKIPADEVCGCPLVRDVFEPTGEYCRVSKRK 500

  Fly   483 CFKHYAWEKIRRAEIDLERVRQWLKMDDLMEQERVMRQQLTSRANLLGLMLHSTYNHEVMDELVR 547
            |.|||.|||:||||:||||||.|.|:|:|.||||.::..:|:||.|:.||.|.|..|:.:...:|
Zfish   501 CNKHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVKTAMTNRAGLMALMPHQTIQHDPITTDLR 565

  Fly   548 KQQE 551
            ..::
Zfish   566 TSKD 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cfp1	NP_572556.1	PHD_Cfp1	62..107	CDD:277028	27/44 (61%)
		zf-CXXC	178..218	CDD:366873	14/46 (30%)
		CpG_bind_C	298..532	CDD:463514	118/234 (50%)
cxxc1a	NP_956893.1	PHD_SF	26..71	CDD:473978	27/44 (61%)
		zf-CXXC	115..162	CDD:366873	14/46 (30%)
		CpG_bind_C	315..550	CDD:463514	118/234 (50%)