Protein Alignment CG31548 and CBR4

DIOPT Version :10

• Sequence 1: NP_730974.1
• Gene: CG31548 / 318794
• FlyBaseID: FBgn0051548
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: XP_006714454.1
• Gene: CBR4 / 84869
• HGNCID: 25891
• Length: 247
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 89/268 - (33%)
• Similarity: 124/268 - (46%)
• Gaps: 52/268 - (19%)

  Fly     6 KVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAE---------CSKVSQSQPALVV 61
            ||..:.|.|.|||.|.|...|:.|..||:..||:|..|..|.:         |
Human     3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSC------------ 55

  Fly    62 GDIAKEADTQRIWSETLQQYGKLDVLVNNAGIIETGTIETTSLEQYDRVMNTNLRAIYHLTMLAT 126
             |:|||.|.|..:.|..:..|:::.|||.|||...|.:..|..|.....::|||..    :||..
Human    56 -DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLG----SMLTC 115

  Fly   127 PELVKTK-----GNIVNVS----------SVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKG 176
            ...::|.     |:||||.          |:.|::...|...|:.||.|:..|:|.:|.|:|.|.
Human   116 KAAMRTMIQQQGGSIVNVGHRREMLLHKRSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKK 180

  Fly   177 VRVNCVNPGVTVTNLHARGGMDAETYKKFLEHSKTTHALGRPGDVKEVAAAIAFLASDEASFSTG 241
            :|||.|.||...|::       .:..|:  ||.|....|||.|:..|||.|:.||.  |:.:.||
Human   181 IRVNVVAPGFVHTDM-------TKDLKE--EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITG 234

  Fly   242 VSLPVDGG 249
            ..|.||||
Human   235 HVLVVDGG 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31548	NP_730974.1	Rossmann-fold NAD(P)(+)-binding proteins	3..253	CDD:473865	89/268 (33%)
CBR4	XP_006714454.1	Rossmann-fold NAD(P)(+)-binding proteins	3..243	CDD:473865	89/268 (33%)