DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31548 and HSDL1

DIOPT Version :9

Sequence 1:NP_730974.1 Gene:CG31548 / 318794 FlyBaseID:FBgn0051548 Length:256 Species:Drosophila melanogaster
Sequence 2:NP_113651.4 Gene:HSDL1 / 83693 HGNCID:16475 Length:330 Species:Homo sapiens


Alignment Length:223 Identity:59/223 - (26%)
Similarity:108/223 - (48%) Gaps:12/223 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 GKVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAECSKVSQSQPALVVGDIAKEAD 69
            |:..:::||:.|||.|.|.:.|..|..:.|..||.|.|:.||.:.:...:.:..::|.|.:...:
Human    67 GRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGRE 131

  Fly    70 TQRIWSETLQQYGKLDVLVNNAGIIETGTIETTSLEQ---YDRVMNTNLRAIYHLTMLATPELV- 130
            ......|.|:. ..:.:||||.|:........|.|.:   :| ::|.|:.|...:..:..|.:| 
Human   132 IYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSEDKLWD-IINVNIAAASLMVHVVLPGMVE 194

  Fly   131 KTKGNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRVNCVNPGVTVTNLHA-- 193
            :.||.||.:||.:..:..|.:.|::.||..:|.|:|.:..|.|:||:.|..:.|....|::.|  
Human   195 RKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTAPS 259

  Fly   194 ----RGGMDAETYKKFLEHSKTTHALGR 217
                |......:.|.:..|:.:|..:.:
Human   260 NFLHRCSWLVPSPKVYAHHAVSTLGISK 287

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31548NP_730974.1 fabG 1..250 CDD:235975 59/223 (26%)
NADB_Rossmann 3..253 CDD:304358 59/223 (26%)
HSDL1NP_113651.4 Required for mitochondria translocation 2..82 6/14 (43%)
17beta-HSD1_like_SDR_c 67..309 CDD:187614 59/223 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D913128at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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