DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31548 and Hsdl2

DIOPT Version :9

Sequence 1:	NP_730974.1	Gene:	CG31548 / 318794	FlyBaseID:	FBgn0051548	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_077217.2	Gene:	Hsdl2 / 72479	MGIID:	1919729	Length:	490	Species:	Mus musculus

Alignment Length:	212	Identity:	66/212 - (31%)
Similarity:	101/212 - (47%)	Gaps:	20/212 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 AGKVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKV------AAECSKVSQSQPALVVG 62
            ||..|.|||||.|||.|.|:|.||.||.:.:..:..:...|:      |||..:.:.......|.
Mouse     9 AGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTTQKHPKLLGTIYTAAEEIEAAGGTALPCVV 73

  Fly    63 DIAKEADTQRIWSETLQQYGKLDVLVNNAGIIE-TGTIETTSLEQYDRVMNTNLRAIYHLTMLAT 126
            |:..|........:.::::|.:|:|||||..|. |.|::|.: ::.|.:||.|.|..|..:....
Mouse    74 DVRDEQQINSAVEKAVEKFGGIDILVNNASAISLTNTLDTPT-KRVDLMMNVNTRGTYLTSKACI 137

  Fly   127 PELVKTK-GNIVNVSSVNGIRS--FPGVLAYNISKMGVDQFTRCVALELAAKGVRVNCVNPGVTV 188
            |.|.|:| |:|:|:|....:..  |....||.|:|.|:......:|.|...: :.||.:.|.
Mouse   138 PFLKKSKVGHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFRGE-IAVNALWPR--- 198

  Fly   189 TNLHAR-----GGMDAE 200
            |.:|..     ||...|
Mouse   199 TAIHTAAMDMLGGSGVE 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31548	NP_730974.1	fabG	1..250	CDD:235975	66/212 (31%)
CG31548	NP_730974.1	NADB_Rossmann	3..253	CDD:304358	66/212 (31%)
Hsdl2	NP_077217.2	HSDL2_SDR_c	8..248	CDD:187663	66/212 (31%)
		adh_short	12..197	CDD:278532	58/186 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	282..370
		SCP2	390..483	CDD:280250
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810