Protein Alignment CG31548 and HSD17B14

DIOPT Version :9

• Sequence 1: NP_730974.1
• Gene: CG31548 / 318794
• FlyBaseID: FBgn0051548
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_057330.2
• Gene: HSD17B14 / 51171
• HGNCID: 23238
• Length: 270
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 89/256 - (34%)
• Similarity: 130/256 - (50%)
• Gaps: 23/256 - (8%)

  Fly     3 FAGKVVLITGASSGIGAATAIKFAKYGACLAL------NGRNVENLKKVAAECSKVSQSQP--AL 59
            :|||||::||...||||.....|...||.:.:      .||.:|             |..|  ..
Human     7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALE-------------QELPGAVF 58

  Fly    60 VVGDIAKEADTQRIWSETLQQYGKLDVLVNNAG-IIETGTIETTSLEQYDRVMNTNLRAIYHLTM 123
            ::.|:.:|.|.:.:.|||::::|:||.:||||| .......|.||.:.:.:::..||...|.||.
Human    59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123

  Fly   124 LATPELVKTKGNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRVNCVNPGVTV 188
            ||.|.|.|::||::|:||:.|.......:.|..:|..|...|:.:||:.:..||||||::||...
Human   124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIW 188

  Fly   189 TNLHARGGMDAETYKKFLEHSKTTHALGRPGDVKEVAAAIAFLASDEASFSTGVSLPVDGG 249
            |.|...........:..:........|||.|...||.||..|||| ||:|.||:.|.|.||
Human   189 TPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGG 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31548	NP_730974.1	fabG	1..250	CDD:235975	89/256 (35%)
		NADB_Rossmann	3..253	CDD:304358	89/256 (35%)
HSD17B14	NP_057330.2	RDH_SDR_c	1..256	CDD:187638	89/256 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	128	1.000	Domainoid score	I5306
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4508
Isobase	1	0.950	-	0.928771	Normalized mean entropy	S6398
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487970at33208
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X68
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.820